Search Results - "Stefanello, Sílvio T."
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Caffeine and acetaminophen association: Effects on mitochondrial bioenergetics
Published in Life sciences (1973) (15-01-2018)“…Many studies have been demonstrating the role of mitochondrial function in acetaminophen (APAP) hepatotoxicity. Since APAP is commonly consumed with caffeine,…”
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MPMT-OX up-regulates GABAergic transmission and protects against seizure-like behavior in Caenorhabditis elegans
Published in Neurotoxicology (Park Forest South) (01-09-2019)“…•The paralysis induced by pentylenetetrazole and aldicarb is attenuated by MPMT-OX treatment.•MPMT-OX increased latency time to the onset of PTZ-induced…”
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Eco-friendly synthesis and antioxidant activity of new trifluoromethyl-substituted N-(pyrimidin-2-yl)benzo[d]thiazol-2-amines and some N-derivatives
Published in Monatshefte für Chemie (01-12-2016)“…A convenient and environmentally benign procedure for the synthesis of a new series of trifluoromethyl-substituted N -(pyrimidin-2-yl)benzo[ d…”
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Impact of Anions on the Partition Constant, Self-Diffusion, Thermal Stability, and Toxicity of Dicationic Ionic Liquids
Published in ACS omega (31-01-2018)“…Partition constants (K D °), molecular dynamics (T 1, T 2, and DOSY measurements), thermal stability, and toxicity of dicationic ionic liquids (ILs) were…”
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Diphenyl diselenide blunts swimming training on mitochondrial liver redox adaptation mechanisms of aged animals
Published in Sport sciences for health (01-06-2020)“…Background Studies about antioxidant supplementation and exercises combined, especially at hepatic liver tissue, are rare and still controversial. In this…”
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N-acetylcysteine does not protect behavioral and biochemical toxicological effect after acute exposure of diphenyl ditelluride
Published in Toxicology mechanisms and methods (01-12-2014)“…Abstract Diphenyl ditelluride (PhTe)2 is a versatile molecule used in the organic synthesis and it is a potential prototype for the development of novel…”
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Synthesis and antioxidant properties of organosulfur and organoselenium compounds derived from 5-substituted-1,3,4-oxadiazole/thiadiazole-2-thiols
Published in Tetrahedron letters (04-01-2017)“…[Display omitted] •The heterocycles were prepared by simple and versatile methods.•The insertion of organochalcogen in the structure was performed in efficient…”
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Phenolic composition and in vitro activity of the Brazilian fruit tree Caryocar coriaceum Wittm
Published in European journal of integrative medicine (01-04-2013)“…Caryocar coriaceum Wittm. (Caryocaraceae) is a plant found in the region of Araripe (Ceará State, Brazil) and is widely used in folk medicine. The present work…”
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Effects of caffeine on brain antioxidant status and mitochondrial respiration in acetaminophen-intoxicated mice
Published in Toxicology research (Cambridge) (01-09-2020)“…Hepatic encephalopathy is a pathophysiological complication of acute liver failure, which may be triggered by hepatotoxic drugs such as acetaminophen (APAP)…”
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Synthesis, Structure Elucidation, Antioxidant and Antimicrobial Activity of Novel 2-(5-Trifluoromethyl-1 H -pyrazol-1-yl)-5-(5-trihalomethyl-1 H -pyrazol-1-yl-1-carbonyl)pyridines
Published in Journal of the Brazilian Chemical Society (01-11-2015)“…This paper describes an efficient approach for the synthesis of a novel series of sixteen…”
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Free radical scavenging in vitro and biological activity of diphenyl diselenide-loaded nanocapsules: DPDS-NCS antioxidant and toxicological effects
Published in International journal of nanomedicine (01-01-2015)“…Selenium compounds, such as diphenyl diselenide (DPDS), have been shown to exhibit biological activity, including antioxidant effects. However, the use of DPDS…”
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