Search Results - "Stefan Pitsch"
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Effect of Polar Faces of SiC on the Epitaxial Growth of Graphene: Growth Mechanism and Its Implications for Structural and Electrical Properties
Published in Crystals (Basel) (01-01-2023)“…In this study, epitaxial graphene layers of cm2 sizes were grown on silicon carbide (SiC) substrates by high-temperature sublimation. The behavior of the two…”
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Photoactivation of silicon rhodamines via a light-induced protonation
Published in Nature communications (08-10-2019)“…Photoactivatable fluorophores are important for single-particle tracking and super-resolution microscopy. Here we present a photoactivatable fluorophore that…”
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Structure of PTB Bound to RNA: Specific Binding and Implications for Splicing Regulation
Published in Science (American Association for the Advancement of Science) (23-09-2005)“…The polypyrimidine tract binding protein (PTB) is a 58-kilodalton RNA binding protein involved in multiple aspects of messenger RNA metabolism, including the…”
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Molecular basis of RNA recognition by the human alternative splicing factor Fox-1
Published in The EMBO journal (11-01-2006)“…The Fox‐1 protein regulates alternative splicing of tissue‐specific exons by binding to GCAUG elements. Here, we report the solution structure of the Fox‐1 RNA…”
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Flipper Probes for the Community
Published in Chimia (22-12-2021)“…This article describes four fluorescent membrane tension probes that have been designed, synthesized, evaluated, commercialized and applied to current biology…”
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Gentle Rhodamines for Live-Cell Fluorescence Microscopy
Published in ACS central science (23-10-2024)“…Rhodamines have been continuously optimized in brightness, biocompatibility, and color to fulfill the demands of modern bioimaging. However, the problem of…”
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Time-resolved NMR studies of RNA folding
Published in Biopolymers (05-08-2007)“…The application of real‐time NMR experiments to the study of RNA folding, as reviewed in this article, is relatively new. For many RNA folding events, current…”
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Kinetics of Photoinduced RNA Refolding by Real-Time NMR Spectroscopy
Published in Angewandte Chemie International Edition (22-04-2005)“…By introducing a photolabile group in the Watson–Crick base‐pairing site of a guanosine residue, a bistable 20‐base RNA sequence was forced into a less stable…”
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NMR-spectroscopic characterisation of phosphodiester bond cleavage catalyzed by the minimal hammerhead ribozyme
Published in RNA biology (01-01-2008)“…In order to relate the conformational dynamics of the hammerhead ribozyme to its biological function the cleavage reaction catalyzed by the hammerhead ribozyme…”
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Kinetics of RNA Refolding in Dynamic Equilibrium by 1H-Detected 15N Exchange NMR Spectroscopy
Published in Journal of the American Chemical Society (14-06-2006)“…By implementing new NMR methods that were designed to map very slow exchange processes we have investigated and characterized the refolding kinetics of a…”
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Protecting Groups for the Synthesis of Ribonucleic Acids
Published in Chimia (01-01-2001)“…Methods for the regioselective introduction of alkoxymethyl-groups into the 2?-O-position of 5?-O-dimethoxytritylated, nucleobase-protected ribonucleosides and…”
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Novel Fluoride-Labile Nucleobase-Protecting Groups for the Synthesis of 3′(2′)-O-Aminoacylated RNA Sequences
Published in Helvetica chimica acta (06-09-2000)“…With the aim to develop a general approach to a total synthesis of aminoacylated t‐RNAs and analogues, we describe the synthesis of stabilized, aminoacylated…”
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Towards a Total Synthesis of Aminoacylated t-RNAs
Published in Chimia (01-01-2001)“…In the ribosomal biosynthesis of proteins, the aminoacylated t-RNAs serve as carriers of the amino acids. A total synthesis of these biological key-compounds…”
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14
A Highly Enantio-Selective Hexitol Nucleic Acid Template for Nonenzymatic Oligoguanylate Synthesis
Published in Journal of the American Chemical Society (10-02-1999)“…The effect of L-guanosine 5'-phosphoro-2-methylimidazole (L-2-MeImpG) on the nonenzymatic oligomerization of the D-enantiomer (Figure 1a) on a poly(D-C)…”
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Oligomerization of Activated D- and L-guanosine Mononucleotides on Templates Containing D- and L-deoxycytidylate Residues
Published in Proceedings of the National Academy of Sciences - PNAS (10-11-1998)“…The oligomerization of activated D- and L- and racemic guanosine-5′-phosphoro-2-methylimidazole on short templates containing D- and L-deoxycytidylate has been…”
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Concentration of Simple Aldehydes by Sulfite-Containing Double-Layer Hydroxide Minerals: Implications for Biopoesis
Published in Helvetica chimica acta (06-09-2000)“…Environmental conditions play an important role in conceptual studies of prebiotically relevant chemical reactions that could have led to functional…”
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Preparation of Modified RNA Sequences for Biological Research
Published in Chimia (01-11-2005)“…Our group is working on the development of reliable access to biologically relevant, long, and modified RNA sequences. Here, we briefly present the chemical…”
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Conformational Dynamics of Bistable RNAs Studied by Time-Resolved NMR Spectroscopy
Published in Journal of the American Chemical Society (26-12-2007)“…The structural transition between two alternate conformations of bistable RNAs has been characterized by time-resolved NMR spectroscopy. The mechanism,…”
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Synthesis of Some D-Ribose Phosphates Synthese einiger Phosphorsäure-Ester der D-Ribose
Published in Chimia (29-06-1999)“…Unambitious syntheses of D-ribose 2-phosphate, 3-phosphate, 4-phosphate, 2,3-diphosphate, 3,4-diphosphate, 2,4-diphosphate, cyclic 2,3-phosphate, cyclic…”
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Fast and Reliable Automated Synthesis of RNA and Partially 2′-O- Protected Precursors (`Caged RNA') Based on Two Novel, Orthogonal 2′-O-Protecting Groups, Preliminary Communication
Published in Helvetica chimica acta (06-10-1999)“…Two sets of RNA phosphoramidites, carrying the (fluoride‐labile) 2′‐O‐[(triisopropylsilyl)oxy]methyl (=tom) group and the (photolabile)…”
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