Search Results - "Stefan Dhein"
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Cardiac Roles of Serotonin (5-HT) and 5-HT-Receptors in Health and Disease
Published in International journal of molecular sciences (01-03-2023)“…Serotonin acts solely via 5-HT -receptors to control human cardiac contractile function. The effects of serotonin via 5-HT -receptors lead to positive…”
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Role of Dopamine in the Heart in Health and Disease
Published in International journal of molecular sciences (01-03-2023)“…Dopamine has effects on the mammalian heart. These effects can include an increase in the force of contraction, and an elevation of the beating rate and the…”
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Remodeling of Cardiac Gap Junctional Cell–Cell Coupling
Published in Cells (Basel, Switzerland) (14-09-2021)“…The heart works as a functional syncytium, which is realized via cell-cell coupling maintained by gap junction channels. These channels connect two adjacent…”
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Effects of mechanical forces and stretch on intercellular gap junction coupling
Published in Biochimica et biophysica acta (01-01-2013)“…Mechanical forces provide fundamental physiological stimulus in living organisms. Recent investigations demonstrated how various types of mechanical load, like…”
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Glucagon and Its Receptors in the Mammalian Heart
Published in International journal of molecular sciences (01-08-2023)“…Glucagon exerts effects on the mammalian heart. These effects include alterations in the force of contraction, beating rate, and changes in the cardiac…”
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Avoiding implantation of a cardioverter-defibrillator by bridging with wearable defibrillator vest
Published in Herz (01-03-2021)“…Background Patients with a left ventricular ejection fraction (LVEF) ≤35% should be protected from sudden cardiac death with an implantable…”
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Neuroprotective Strategies during Cardiac Surgery with Cardiopulmonary Bypass
Published in International journal of molecular sciences (21-11-2016)“…Aortocoronary bypass or valve surgery usually require cardiac arrest using cardioplegic solutions. Although, in principle, in a number of cases beating heart…”
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Effects of hallucinogenic drugs on the human heart
Published in Frontiers in pharmacology (2024)“…Hallucinogenic drugs are used because they have effects on the central nervous system. Their hallucinogenic effects probably occur via stimulation of serotonin…”
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Function and Role of Histamine H1 Receptor in the Mammalian Heart
Published in Pharmaceuticals (Basel, Switzerland) (11-05-2023)“…Histamine can change the force of cardiac contraction and alter the beating rate in mammals, including humans. However, striking species and regional…”
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The Roles of Cardiovascular H2-Histamine Receptors Under Normal and Pathophysiological Conditions
Published in Frontiers in pharmacology (20-12-2021)“…This review addresses pharmacological, structural and functional relationships among H 2 -histamine receptors and H 1 -histamine receptors in the mammalian…”
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Infection and transmission risks of COVID-19 in schools and their contribution to population infections in Germany: A retrospective observational study using nationwide and regional health and education agency notification data
Published in PLoS medicine (20-12-2022)“…School-level infection control measures in Germany during the early Coronavirus Disease 2019 (COVID-19) pandemic differed across the 16 federal states and…”
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Changes in causes and age of death in an eastern German county over a period of 14 years. Comparison of rural and urban populations. Focus on COPD and ischemic heart disease
Published in Journal of public health (01-08-2021)“…Aim We aimed to determine whether the causes of death, age of death and burden of disease have changed in the last years and whether there are differences…”
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Engineered heart tissue grafts improve systolic and diastolic function in infarcted rat hearts
Published in Nature medicine (01-04-2006)“…The concept of regenerating diseased myocardium by implantation of tissue-engineered heart muscle is intriguing, but convincing evidence is lacking that heart…”
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Pharmacology of Gap junctions. New pharmacological targets for treatment of arrhythmia, seizure and cancer?
Published in Biochimica et biophysica acta (20-12-2005)“…Intercellular communication in many organs is maintained via intercellular gap junction channels composed of connexins, a large protein family with a number of…”
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Epigallocatechin Gallate Reduces Ischemia/Reperfusion Injury in Isolated Perfused Rabbit Hearts
Published in International journal of molecular sciences (23-02-2018)“…Cardioplegic arrest during heart operations is often used in cardiac surgery. During cardioplegia, the heart is subjected to a global…”
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Cyclic Mechanical Stretch Induces Cardiomyocyte Orientation and Polarization of the Gap Junction Protein Connexin43
Published in Circulation research (28-05-2010)“…RATIONALE:Cyclic mechanical stretch (CMS) is an important physiological and pathological factor in the heart. OBJECTIVE:We examined whether CMS can affect…”
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Protective Effects of Pulsatile Flow During Cardiopulmonary Bypass
Published in The Annals of thoracic surgery (2015)“…Background Children with congenital heart disease are often operated at a very young age. Cardiopulmonary bypass (CPB) has become indispensable for these…”
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Development of a constant pressure perfused ex vivo model of the equine larynx
Published in PloS one (20-05-2021)“…Distal axonopathy is seen in a broad range of species including equine patients. In horses, this degenerative disorder of the recurrent laryngeal nerve is…”
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Connexins in Cardiovascular and Neurovascular Health and Disease: Pharmacological Implications
Published in Pharmacological reviews (01-10-2017)Get full text
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Histamine can be Formed and Degraded in the Human and Mouse Heart
Published in Frontiers in pharmacology (11-05-2021)“…Histamine is metabolized by several enzymes in vitro and in vivo . The relevance of this metabolism in the mammalian heart in vivo is unclear. However,…”
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