Search Results - "Steephan, Mathew"

Multicomponent reactions for the synthesis of tetrazole derivatives: Discovery and validation of a novel anticancer agent active against ER positive cancers by Prabhu, Deepak J., John, Franklin, Steephan, Mathew, John, Jinju, Sreehari, A.P., Chandrika, Bhavya B.

“…[Display omitted] Chemotherapy is an indispensable tool in medicine where small molecules act as potential cytotoxic, apoptotic, anti-angiogenic and…”
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Hesperetin and Naringenin sensitize HER2 positive cancer cells to death by serving as HER2 Tyrosine Kinase inhibitors by Chandrika, Bhavya Balan, Steephan, Mathew, Kumar, T.R. Santhosh, Sabu, A., Haridas, M.

“…Aberrant human epidermal growth factor receptor-2 (HER2) expression and constitutive mutant activation of its tyrosine kinase domain account for tumor…”
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A simple end-point assay for calcium channel activity by Chandrika, Arunkumar Renganathan, Steephan, Mathew, Raveendran Nair, Rajeevkumar, Sudarsana Devi, Suma Priya, Kumar, Mantosh, Paul, Soumya, Madhavan, Mayadevi, Omkumar, Ramakrishnapillai V.

“…[Display omitted] •Novel end-point detection based method for intracellular calcium sensing.•Technically simple to perform, less expensive and adaptable to…”
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Overexpression of the large‐conductance, Ca 2+ ‐activated K + (BK) channel shortens action potential duration in HL‐1 cardiomyocytes by Rhee, Sung W, Song, Li, Steephan, Mathew, Rusch, Nancy J, Stimers, Joseph R

“…Abstract only Hereditary long‐QT syndrome (LQTS) is caused by mutations in ion channel genes resulting in a prolonged action potential duration (APD) in…”
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Phosphorylation status of the NR2B subunit of NMDA receptor regulates its interaction with calcium/calmodulin-dependent protein kinase II by Raveendran, Rajeevkumar, Devi Suma Priya, Sudarsana, Mayadevi, Madhavan, Steephan, Mathew, Santhoshkumar, Thankayyan R, Cheriyan, John, Sanalkumar, Rajendran, Pradeep, Kurup K, James, Jackson, Omkumar, Ramakrishnapillai V

“…Ca²⁺ influx through NMDA-type glutamate receptor at excitatory synapses causes activation of post-synaptic Ca²⁺/calmodulin-dependent protein kinase type II…”
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