Search Results - "Steenkamp, V."
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In vitro screening for acetylcholinesterase inhibition and antioxidant activity of medicinal plants from southern Africa
Published in Asian Pacific journal of tropical medicine (01-10-2011)“…To determine the acetylcholinesterase inhibitory (AChEI) and antioxidant activity of the ethyl acetate and methanol extracts of 12 traditional medicinal plants…”
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Traditional herbal remedies used by South African women for gynaecological complaints
Published in Journal of ethnopharmacology (01-05-2003)“…Traditional remedies are part of the cultural and religious life of the African people. In this manuscript the nature and range of traditional remedies used…”
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Underlying mechanisms of cytotoxicity in HepG2 hepatocarcinoma cells exposed to arsenic, cadmium and mercury individually and in combination
Published in Toxicology in vitro (01-04-2021)“…Toxicity data regarding combinational exposure of humans to arsenic, cadmium and mercury is scarce. Although hepatotoxicity has been reported, limited…”
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Use of Yokukansan (TJ-54) in the treatment of neurological disorders: a review
Published in Phytotherapy research (01-09-2010)“…Kampo herbal remedies are reported to have a wide range of indications and have attracted attention due to reports suggesting that these remedies are effective…”
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Antioxidant and acetylcholinesterase inhibitory activity of selected southern African medicinal plants
Published in South African journal of botany (01-08-2011)“…Alzheimer's disease (AD) is the most common type of dementia in the aging population. Enhancement of acetylcholine levels in the brain is one means of treating…”
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Evaluation of Athrixia bush tea for cytotoxicity, antioxidant activity, caffeine content and presence of pyrrolizidine alkaloids
Published in Journal of ethnopharmacology (01-03-2007)“…In South Africa, Athrixia phylicoides DC. (bush tea) is widely used as a beverage, cough remedy and purgative. The commercialization of this tea in a similar…”
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Pyrrolizidine alkaloids enhance alcohol-induced hepatocytotoxicity in vitro in normal human hepatocytes
Published in European review for medical and pharmacological sciences (01-03-2017)“…Herbal remedies containing pyrrilidozine alkaloids (PA)s can induce liver damage, including hepato-sinusoidal obstruction syndrome (HSOS) or veno-occlusive…”
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Effect of an alkaloidal fraction of Tabernaemontana elegans (Stapf.) on selected micro-organisms
Published in Journal of ethnopharmacology (27-03-2012)“…Bacterial infections remain a significant threat to human health. Due to the emergence of widespread antibiotic resistance, development of novel antibiotics is…”
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Studies on antibacterial, antioxidant and fibroblast growth stimulation of wound healing remedies from South Africa
Published in Journal of ethnopharmacology (01-12-2004)“…Aqueous and methanol extracts of Urtica urens, Capparis tomentosa, Dicoma anomala, Leonotis leonorus, Xysmalobium undulatum, Helichrysum foetidum, Pterocarpus…”
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Polyamidoamine-Drug Conjugates Containing Metal-Based Anticancer Compounds
Published in Journal of inorganic and organometallic polymers and materials (01-05-2020)“…Polyamidoamine drug conjugates containing ferrocene and platinum analogues were prepared in this study. Fourier transform infrared spectra confirmed the…”
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Important pharmacogenomic aspects in the management of HIV/AIDS
Published in South African family practice (08-03-2019)“…In managing HIV/AIDS with highly active antiretroviral agents, the historical therapeutic aim remains to maintain the plasma concentrations at a level above…”
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Fatalities involving illicit drug use in Pretoria, South Africa, for the period 2003 - 2012
Published in South African medical journal (01-10-2016)“…Globally, illicit drugs are responsible for many fatalities annually, yet accurate data on the nature and extent of these deaths in South Africa (SA) are…”
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Studies on antibacterial, anti-inflammatory and antioxidant activity of herbal remedies used in the treatment of benign prostatic hyperplasia and prostatitis
Published in Journal of ethnopharmacology (03-01-2006)“…Crude water and ethanolic extracts of five herbal remedies reported in the literature for traditional treatment of benign prostatic hyperplasia (BPH) and/or…”
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In vitro effect of N-acetylcysteine on hepatocyte injury caused by dichlorodiphenyltrichloroethane and its metabolites
Published in Human & experimental toxicology (01-01-2014)“…The organochlorine pesticide, dichlorodiphenyltrichloroethane (DDT), is still used to combat the spread of malaria in several developing countries despite its…”
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In-vitro bioactivity of Venda medicinal plants used in the treatment of respiratory conditions
Published in Human & experimental toxicology (01-11-2008)“…Infectious diseases, especially those affecting the respiratory tract, represent a critical problem to health. Crude methanol and water extracts of 10 Venda…”
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STANDARDIZATION OF CASSAVA MAHEWU FERMENTATION AND ASSESSMENT OF THE EFFECTS OF IRON SOURCES USED FOR FORTIFICATION
Published in African journal of food, agriculture, nutrition, and development : AJFAND (01-06-2016)“…Cassava root is the main staple for 70% of the population in Mozambique, particularly in inaccessible rural areas, but is known to be low in iron. Anaemia is a…”
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Screening of Venda medicinal plants for antifungal activity against Candida albicans
Published in South African journal of botany (01-04-2007)“…Crude methanol and water extracts of 32 plant species, used for the treatment of infectious diseases in Venda, were screened for in vitro activity against…”
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The ability of Warburgia salutaris extracts to protect against crystalline silica-induced cell injury
Published in Human & experimental toxicology (01-11-2008)“…In Southern Africa, the medicinal plant Warburgia salutaris is commonly used for the treatment of inflammatory and other diseases. The methanol extracts of W…”
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Hepatic veno-occlusive disease as a result of a traditional remedy: confirmation of toxic pyrrolizidine alkaloids as the cause, using an in vitro technique
Published in Journal of clinical pathology (01-09-2002)“…Background/Aims: A child presented with hepatic veno-occlusive disease after having been administered a short course of treatment with a traditional herbal…”
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