Search Results - "Steel, H H"

HIV as a Cause of Immune Activation and Immunosenescence by Rossouw, Theresa M., Nieuwoudt, M., Steel, Helen C., Sokoya, T.

“…Systemic immune activation has emerged as an essential component of the immunopathogenesis of HIV. It not only leads to faster disease progression, but also to…”
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Retinal detachment following cataract phacoemulsification—a review of the literature by Qureshi, M. Hamza, Steel, David H. W.

“…A link between cataract surgery and rhegmatogenous retinal detachment (RRD) has long been considered. Indeed, pseudophakic retinal detachment (PPRD) forms a…”
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Emerging markers of cancer cachexia and their relationship to sarcopenia by Lipshitz, Melanie, Visser, J., Anderson, R., Nel, D. G., Smit, T., Steel, H. C., Rapoport, B.

“…Purpose Emerging biomarkers of cancer cachexia and their roles in sarcopenia and prognosis are poorly understood. Baseline assessments of anthropometrics,…”
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Reshaping ophthalmology training after COVID-19 pandemic by Ferrara, Mariantonia, Romano, Vito, Steel, David H, Gupta, Rajen, Iovino, Claudio, van Dijk, Elon H. C., Romano, Mario R.

“…Background The coronavirus disease 2019 (COVID-19) pandemic has had a significant impact on practical activities and didactic teaching of residents and…”
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Idiopathic vitreomacular traction and macular hole: a comprehensive review of pathophysiology, diagnosis, and treatment by Steel, D H W, Lotery, A J

“…Posterior vitreous detachment (PVD) is a common phenomenon in the aging eye. However, this may be complicated by persistent symptomatic vitreomacular adhesions…”
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Cellular regeneration strategies for macular degeneration: past, present and future by Chichagova, Valeria, Hallam, Dean, Collin, Joseph, Zerti, Darin, Dorgau, Birthe, Felemban, Majed, Lako, Majlinda, Steel, David H.

“…Despite considerable effort and significant therapeutic advances, age-related macular degeneration (AMD) remains the commonest cause of blindness in the…”
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Subretinal injection under perfluorocarbon liquids to avoid foveal dehiscence by Steel, David H, Geraghty, Brendan, Kearns, Victoria, Stanzel, Boris, Wong, David

“…To describe a novel method of subretinal injection to reduce the risk of foveal dehiscence during subretinal tissue plasminogen activator (TPA) delivery for…”
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IGF‐1 Signaling Plays an Important Role in the Formation of Three‐Dimensional Laminated Neural Retina and Other Ocular Structures From Human Embryonic Stem Cells by Mellough, Carla B., Collin, Joseph, Khazim, Mahmoud, White, Kathryn, Sernagor, Evelyne, Steel, David H. W., Lako, Majlinda

“…We and others have previously demonstrated that retinal cells can be derived from human embryonic stem cells (hESCs) and induced pluripotent stem cells under…”
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Factors affecting anatomical and visual outcome after macular hole surgery: findings from a large prospective UK cohort by Steel, D. H., Donachie, P. H. J., Aylward, G. W., Laidlaw, D. A., Williamson, T. H., Yorston, D.

“…Objectives To reassess the definition of a large macular hole, factors predicting hole closure and post-surgery visual recovery. Design Database study of 1483…”
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Biomechanical properties of retina and choroid: a comprehensive review of techniques and translational relevance by Ferrara, Mariantonia, Lugano, Gaia, Sandinha, Maria Teresa, Kearns, Victoria R., Geraghty, Brendan, Steel, David H. W.

“…Studying the biomechanical properties of biological tissue is crucial to improve our understanding of disease pathogenesis. The biomechanical characteristics…”
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Vitreous protein networks around ANG2 and VEGF in proliferative diabetic retinopathy and the differential effects of aflibercept versus bevacizumab pre-treatment by Klaassen, Ingeborg, Avery, Peter, Schlingemann, Reinier O., Steel, David H. W.

“…Extracellular signalling proteins interact in networks rather than in isolation. In this context we investigated vitreous protein levels, including placental…”
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INTERNAL LIMITING MEMBRANE PEELING IN MACULAR HOLE SURGERY; WHY, WHEN, AND HOW? by Chatziralli, Irini P, Theodossiadis, Panagiotis G, Steel, David H W

“…To review the current rationale for internal limiting membrane (ILM) peeling in macular hole (MH) surgery and to discuss the evidence base behind why, when,…”
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The RNA-binding protein LARP1 is a post-transcriptional regulator of survival and tumorigenesis in ovarian cancer by Hopkins, Thomas G, Mura, Manuela, Al-Ashtal, Hiba A, Lahr, Roni M, Abd-Latip, Normala, Sweeney, Katrina, Lu, Haonan, Weir, Justin, El-Bahrawy, Mona, Steel, Jennifer H, Ghaem-Maghami, Sadaf, Aboagye, Eric O, Berman, Andrea J, Blagden, Sarah P

“…RNA-binding proteins (RBPs) are increasingly identified as post-transcriptional drivers of cancer progression. The RBP LARP1 is an mRNA stability regulator,…”
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An integrated transcriptional analysis of the developing human retina by Mellough, Carla B, Bauer, Roman, Collin, Joseph, Dorgau, Birthe, Zerti, Darin, Dolan, David W P, Jones, Carl M, Izuogu, Osagie G, Yu, Min, Hallam, Dean, Steyn, Jannetta S, White, Kathryn, Steel, David H, Santibanez-Koref, Mauro, Elliott, David J, Jackson, Michael S, Lindsay, Susan, Grellscheid, Sushma, Lako, Majlinda

“…The scarcity of embryonic/foetal material as a resource for direct study means that there is still limited understanding of human retina development. Here, we…”
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ARL3 Mutations Cause Joubert Syndrome by Disrupting Ciliary Protein Composition by Alkanderi, Sumaya, Molinari, Elisa, Shaheen, Ranad, Elmaghloob, Yasmin, Stephen, Louise A., Sammut, Veronica, Ramsbottom, Simon A., Srivastava, Shalabh, Cairns, George, Edwards, Noel, Rice, Sarah J., Ewida, Nour, Alhashem, Amal, White, Kathryn, Miles, Colin G., Steel, David H., Alkuraya, Fowzan S., Ismail, Shehab, Sayer, John A.

“…Joubert syndrome (JBTS) is a genetically heterogeneous autosomal-recessive neurodevelopmental ciliopathy. We investigated further the underlying genetic…”
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Uterine Selection of Human Embryos at Implantation by Brosens, Jan J., Salker, Madhuri S., Teklenburg, Gijs, Nautiyal, Jaya, Salter, Scarlett, Lucas, Emma S., Steel, Jennifer H., Christian, Mark, Chan, Yi-Wah, Boomsma, Carolien M., Moore, Jonathan D., Hartshorne, Geraldine M., Šućurović, Sandra, Mulac-Jericevic, Biserka, Heijnen, Cobi J., Quenby, Siobhan, Groot Koerkamp, Marian J., Holstege, Frank C. P., Shmygol, Anatoly, Macklon, Nick S.

“…Human embryos frequently harbor large-scale complex chromosomal errors that impede normal development. Affected embryos may fail to implant although many first…”
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Relationships of emerging biomarkers of cancer cachexia with quality of life, appetite, and cachexia by Lipshitz, M., Visser, J., Anderson, R., Nel, DG, Smit, T., Steel, HC, Rapoport, BL

“…Purpose Quality of life (QoL), appetite, cachexia, and biomarkers [albumin, hemoglobin (Hb), neutrophils, lymphocytes, platelets, C-reactive protein (CRP),…”
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Differential epigenetic reprogramming in response to specific endocrine therapies promotes cholesterol biosynthesis and cellular invasion by Nguyen, Van T. M., Barozzi, Iros, Faronato, Monica, Lombardo, Ylenia, Steel, Jennifer H., Patel, Naina, Darbre, Philippa, Castellano, Leandro, Győrffy, Balázs, Woodley, Laura, Meira, Alba, Patten, Darren K., Vircillo, Valentina, Periyasamy, Manikandan, Ali, Simak, Frige, Gianmaria, Minucci, Saverio, Coombes, R. Charles, Magnani, Luca

“…Endocrine therapies target the activation of the oestrogen receptor alpha (ERα) via distinct mechanisms, but it is not clear whether breast cancer cells can…”
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Disordered IL-33/ST2 activation in decidualizing stromal cells prolongs uterine receptivity in women with recurrent pregnancy loss by Salker, Madhuri S, Nautiyal, Jaya, Steel, Jennifer H, Webster, Zoe, Sućurović, Sandra, Nicou, Marilena, Singh, Yogesh, Lucas, Emma S, Murakami, Keisuke, Chan, Yi-Wah, James, Sean, Abdallah, Yazan, Christian, Mark, Croy, B Anne, Mulac-Jericevic, Biserka, Quenby, Siobhan, Brosens, Jan J

“…Decidualization renders the endometrium transiently receptive to an implanting blastocyst although the underlying mechanisms remain incompletely understood…”
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3D culture of human pluripotent stem cells in RGD-alginate hydrogel improves retinal tissue development by Hunt, Nicola C., Hallam, Dean, Karimi, Ayesha, Mellough, Carla B., Chen, Jinju, Steel, David H.W., Lako, Majlinda

“…[Display omitted] No treatments exist to effectively treat many retinal diseases. Retinal pigmented epithelium (RPE) and neural retina can be generated from…”
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