Search Results - "Steckler, Thomas"

The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research by Percie du Sert, Nathalie, Hurst, Viki, Ahluwalia, Amrita, Alam, Sabina, Avey, Marc T, Baker, Monya, Browne, William J, Clark, Alejandra, Cuthill, Innes C, Dirnagl, Ulrich, Emerson, Michael, Garner, Paul, Holgate, Stephen T, Howells, David W, Karp, Natasha A, Lazic, Stanley E, Lidster, Katie, MacCallum, Catriona J, Macleod, Malcolm, Pearl, Esther J, Petersen, Ole H, Rawle, Frances, Reynolds, Penny, Rooney, Kieron, Sena, Emily S, Silberberg, Shai D, Steckler, Thomas, Würbel, Hanno

“…Reproducible science requires transparent reporting. The ARRIVE guidelines (Animal Research: Reporting of In Vivo Experiments) were originally developed in…”
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Reporting animal research: Explanation and elaboration for the ARRIVE guidelines 2.0 by Percie du Sert, Nathalie, Ahluwalia, Amrita, Alam, Sabina, Avey, Marc T, Baker, Monya, Browne, William J, Clark, Alejandra, Cuthill, Innes C, Dirnagl, Ulrich, Emerson, Michael, Garner, Paul, Holgate, Stephen T, Howells, David W, Hurst, Viki, Karp, Natasha A, Lazic, Stanley E, Lidster, Katie, MacCallum, Catriona J, Macleod, Malcolm, Pearl, Esther J, Petersen, Ole H, Rawle, Frances, Reynolds, Penny, Rooney, Kieron, Sena, Emily S, Silberberg, Shai D, Steckler, Thomas, Würbel, Hanno

“…Improving the reproducibility of biomedical research is a major challenge. Transparent and accurate reporting is vital to this process; it allows readers to…”
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Pharmacological treatment of PTSD – Established and new approaches by Steckler, Thomas, Risbrough, Victoria

“…A large proportion of humans will experience a traumatic event at least once in their lifetime, with up to 10% then going on to developing posttraumatic stress…”
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The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research by Percie du Sert, Nathalie, Hurst, Viki, Ahluwalia, Amrita, Alam, Sabina, Avey, Marc T., Baker, Monya, Browne, William J., Clark, Alejandra, Cuthill, Innes C., Dirnagl, Ulrich, Emerson, Michael, Garner, Paul, Holgate, Stephen T., Howells, David W., Karp, Natasha A., Lazic, Stanley E., Lidster, Katie, MacCallum, Catriona J., Macleod, Malcolm, Pearl, Esther J., Petersen, Ole H., Rawle, Frances, Reynolds, Penny, Rooney, Kieron, Sena, Emily S., Silberberg, Shai D., Steckler, Thomas, Würbel, Hanno

“…Reproducible science requires transparent reporting. The ARRIVE guidelines (Animal Research: Reporting of In Vivo Experiments) were originally developed in…”
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The ARRIVE guidelines 2.0: updated guidelines for reporting animal research by Percie du Sert, Nathalie, Hurst, Viki, Ahluwalia, Amrita, Alam, Sabina, Avey, Marc T., Baker, Monya, Browne, William J., Clark, Alejandra, Cuthill, Innes C., Dirnagl, Ulrich, Emerson, Michael, Garner, Paul, Holgate, Stephen T., Howells, David W., Karp, Natasha A., Lazic, Stanley E., Lidster, Katie, MacCallum, Catriona J., Macleod, Malcolm, Pearl, Esther J., Petersen, Ole H., Rawle, Frances, Reynolds, Penny, Rooney, Kieron, Sena, Emily S., Silberberg, Shai D., Steckler, Thomas, Würbel, Hanno

“…Reproducible science requires transparent reporting. The ARRIVE guidelines (Animal Research: Reporting of In Vivo Experiments) were originally developed in…”
Get full text

The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research by Percie du Sert, Nathalie, Hurst, Viki, Ahluwalia, Amrita, Alam, Sabina, Avey, Marc T., Baker, Monya, Browne, William J., Clark, Alejandra, Cuthill, Innes C., Dirnagl, Ulrich, Emerson, Michael, Garner, Paul, Holgate, Stephen T., Howells, David W., Karp, Natasha A., Lazic, Stanley E., Lidster, Katie, MacCallum, Catriona J., Macleod, Malcolm, Pearl, Esther J., Petersen, Ole H., Rawle, Frances, Reynolds, Penny, Rooney, Kieron, Sena, Emily S., Silberberg, Shai D., Steckler, Thomas, Würbel, Hanno

“…Reproducible science requires transparent reporting. The ARRIVE guidelines (Animal Research: Reporting of In Vivo Experiments) were originally developed in…”
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Negative symptoms of schizophrenia: Clinical characteristics, pathophysiological substrates, experimental models and prospects for improved treatment by Millan, Mark J, Fone, Kevin, Steckler, Thomas, Horan, William P

“…Abstract Schizophrenia is a complex and multifactorial disorder generally diagnosed in young adults at the time of the first psychotic episode of delusions and…”
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The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research by Percie du Sert, Nathalie, Hurst, Viki, Ahluwalia, Amrita, Alam, Sabina, Avey, Marc T, Baker, Monya, Browne, William J, Clark, Alejandra, Cuthill, Innes C, Dirnagl, Ulrich, Emerson, Michael, Garner, Paul, Holgate, Stephen T, Howells, David W, Karp, Natasha A, Lazic, Stanley E, Lidster, Katie, MacCallum, Catriona J, Macleod, Malcolm, Pearl, Esther J, Petersen, Ole H, Rawle, Frances, Reynolds, Penny, Rooney, Kieron, Sena, Emily S, Silberberg, Shai D, Steckler, Thomas, Würbel, Hanno

“…Reproducible science requires transparent reporting. The ARRIVE guidelines (Animal Research: Reporting of In Vivo Experiments) were originally developed in…”
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NMDA receptors, cognition and schizophrenia – Testing the validity of the NMDA receptor hypofunction hypothesis by Gilmour, Gary, Dix, Sophie, Fellini, Laetitia, Gastambide, Francois, Plath, Niels, Steckler, Thomas, Talpos, John, Tricklebank, Mark

“…Cognitive dysfunction is core to schizophrenia, and remains poorly treated by existing therapies. A prominent hypothesis suggests that many symptoms arise from…”
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Metabolomic biosignature differentiates melancholic depressive patients from healthy controls by Liu, Yashu, Yieh, Lynn, Yang, Tao, Drinkenburg, Wilhelmus, Peeters, Pieter, Steckler, Thomas, Narayan, Vaibhav A, Wittenberg, Gayle, Ye, Jieping

“…Major depressive disorder (MDD) is a heterogeneous disease at the level of clinical symptoms, and this heterogeneity is likely reflected at the level of…”
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Nicotine Improves Working Memory Span Capacity in Rats Following Sub-Chronic Ketamine Exposure by RUSHFORTH, Samantha L, STECKLER, Thomas, SHOAIB, Mohammed

“…Ketamine, an NMDA-receptor antagonist, produces cognitive deficits in humans in a battery of tasks involving attention and memory. Nicotine can enhance various…”
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PEERS - An Open Science "Platform for the Exchange of Experimental Research Standards" in Biomedicine by Sil, Annesha, Bespalov, Anton, Dalla, Christina, Ferland-Beckham, Chantelle, Herremans, Arnoud, Karantzalos, Konstantinos, Kas, Martien J, Kokras, Nikolaos, Parnham, Michael J, Pavlidi, Pavlina, Pristouris, Kostis, Steckler, Thomas, Riedel, Gernot, Emmerich, Christoph H

“…Laboratory workflows and preclinical models have become increasingly diverse and complex. Confronted with the dilemma of a multitude of information with…”
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Corticotropin-releasing hormone receptor subtypes and emotion by Steckler, Thomas, Holsboer, Florian

“…Preclinical data indicate that corticotropin-releasing hormone (CRH) has anxiogenic properties and a dysregulation in CRH systems has been suggested to play a…”
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The preclinical data forum network: A new ECNP initiative to improve data quality and robustness for (preclinical) neuroscience by Steckler, Thomas, Brose, Katja, Haas, Magali, Kas, Martien J, Koustova, Elena, Bespalov, Anton

“…Abstract Current limitations impeding on data reproducibility are often poor statistical design, underpowered studies, lack of robust data, lack of…”
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In vivo electroporation of the central nervous system: a non-viral approach for targeted gene delivery by De Vry, Jochen, Martínez-Martínez, Pilar, Losen, Mario, Temel, Yasin, Steckler, Thomas, Steinbusch, Harry W M, De Baets, Marc H, Prickaerts, Jos

“…Electroporation is a widely used technique for enhancing the efficiency of DNA delivery into cells. Application of electric pulses after local injection of DNA…”
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Blocking melanin-concentrating hormone MCH1 receptor affects rat sleep-wake architecture by AHNAOU, Abdellah, DRINKENBURG, Wilhelmus H. I. M, ADRIAAN BOUWKNECHT, J, ALCAZAR, Jesus, STECKLER, Thomas, DAUTZENBERG, Frank M

“…Melanin-concentrating hormone (MCH) is a hypothalamic peptide that centrally regulates food intake, energy balance and emotion. Interestingly, MCH and…”
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Metabotropic glutamate mGlu1 receptor stimulation and blockade: Therapeutic opportunities in psychiatric illness by Lesage, Anne, Steckler, Thomas

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Modulation of group II metabotropic glutamate receptor (mGlu 2) elicits common changes in rat and mice sleep–wake architecture by Ahnaou, Abdellah, Dautzenberg, Frank M., Geys, Helena, Imogai, Hassan, Gibelin, Antoine, Moechars, Dieder, Steckler, Thomas, Drinkenburg, Wilhelmus H.I.M.

“…Compiling pharmacological evidence implicates metabotropic glutamate mGlu 2 receptors in the regulation of emotional states and suggests positive modulators as…”
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Impaired stress response and reduced anxiety in mice lacking a functional corticotropin-releasing hormone receptor 1 by Wurst, Wolfgang, Timpl, Peter, Spanagel, Rainer, Sillaber, Inge, Kresse, Adelheid, Reul, Johannes M. H. M, Stalla, Günter K, Blanquet, Veronique, Steckler, Thomas, Holsboer, Florian

“…Corticotropin-releasing hormone (CRH) is a potent mediator of endocrine, autonomic, behavioural and immune responses to stress, and has been implicated in the…”
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IMPA1 is essential for embryonic development and lithium-like pilocarpine sensitivity by Cryns, Kim, Shamir, Alon, Van Acker, Nathalie, Levi, Itzhak, Daneels, Guy, Goris, Ilse, Bouwknecht, J Adriaan, Andries, Luc, Kass, Stefan, Agam, Galila, Belmaker, Haim, Bersudsky, Yuly, Steckler, Thomas, Moechars, Dieder

“…Lithium has been the standard pharmacological treatment for bipolar disorder over the last 50 years; however, the molecular targets through which lithium…”
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