Search Results - "Stebbins, C C"

Masters of Disguise: Antigenic Variation and the VSG Coat in Trypanosoma brucei by Mugnier, Monica R, Stebbins, C Erec, Papavasiliou, F Nina

“…[...]at lower antibody concentrations, antibody degradation by T.\n It is also unclear exactly how other factors, such as quorum sensing [19] or the movement…”
Get full text

family of Salmonella virulence factors functions as a distinct class of autoregulated E3 ubiquitin ligases by Quezada, Cindy M, Hicks, Stuart W, Galán, Jorge E, Stebbins, C. Erec

“…Processes as diverse as receptor binding and signaling, cytoskeletal dynamics, and programmed cell death are manipulated by mimics of host proteins encoded by…”
Get full text

A common assembly module in injectisome and flagellar type III secretion sorting platforms by Notti, Ryan Q., Bhattacharya, Shibani, Lilic, Mirjana, Stebbins, C. Erec

“…Translocating proteins across the double membrane of Gram-negative bacteria, type III secretion systems (T3SS) occur in two evolutionarily related forms:…”
Get full text

Structure of the Helicobacter pylori CagA oncoprotein bound to the human tumor suppressor ASPP2 by Nešić, Dragana, Buti, Ludovico, Lu, Xin, Stebbins, C. Erec

“…The Cytotoxin associated gene A (CagA) protein of Helicobacter pylori is associated with increased virulence and risk of cancer. Recent proteomic studies have…”
Get full text

Type III secretion systems shape up as they ship out by Marlovits, Thomas C, Stebbins, C Erec

“…Virulence associated protein type III secretion systems (T3SSs) are intricately structured organic nanosyringes that achieve the translocation of bacterial…”
Get full text

The Structure and Function of Type III Secretion Systems by Notti, Ryan Q, Stebbins, C Erec

“…Type III secretion systems (T3SSs) afford Gram-negative bacteria an intimate means of altering the biology of their eukaryotic hosts--the direct delivery of…”
Get more information

Structural similarities between the metacyclic and bloodstream form variant surface glycoproteins of the African trypanosome by Chandra, Monica, Đaković, Sara, Foti, Konstantina, Zeelen, Johan P, van Straaten, Monique, Aresta-Branco, Francisco, Tihon, Eliane, Lübbehusen, Nicole, Ruppert, Thomas, Glover, Lucy, Papavasiliou, F Nina, Stebbins, C Erec

“…During infection of mammalian hosts, African trypanosomes thwart immunity using antigenic variation of the dense Variant Surface Glycoprotein (VSG) coat,…”
Get full text

Structure of the HopA1(21-102)-ShcA Chaperone-Effector Complex of Pseudomonas syringae Reveals Conservation of a Virulence Factor Binding Motif from Animal to Plant Pathogens by Janjusevic, Radmila, Quezada, Cindy M, Small, Jennifer, Stebbins, C. Erec

“…Pseudomonas syringae injects numerous bacterial proteins into host plant cells through a type 3 secretion system (T3SS). One of the first such bacterial…”
Get full text

Mechanistic Similarities between Antigenic Variation and Antibody Diversification during Trypanosoma brucei Infection by Aresta-Branco, Francisco, Erben, Esteban, Papavasiliou, F. Nina, Stebbins, C. Erec

“…Trypanosoma brucei, which causes African trypanosomiasis, avoids immunity by periodically switching its surface composition. The parasite is coated by 10…”
Get full text

Bacterial Inhibitor of Host Programmed Cell Death Defenses Is an E3 Ubiquitin Ligase by Janjusevic, Radmila, Abramovitch, Robert B, Martin, Gregory B, Stebbins, C. Erec

“…The Pseudomonas syringae protein AvrPtoB is translocated into plant cells, where it inhibits immunity-associated programmed cell death (PCD). The structure of…”
Get full text

The fentanyl-specific antibody FenAb024 can shield against carfentanil effects by Urban, Katharina, Gkeka, Anastasia, Chandra, Monica, Greiner, Dennis, Pollich, Selina, Ruf, Sandra, Kelemen, Yosip, Sundermann, Tom, Pravetoni, Marco, Baehr, Carly, Stebbins, C. Erec, Papavasiliou, F. Nina, Verdi, Joseph P.

“…The surge in opioid-related deaths, driven predominantly by fentanyl and its synthetic derivatives, has become a critical public health concern, which is…”
Get full text

Maintenance of an unfolded polypeptide by a cognate chaperone in bacterial type III secretion by Galán, Jorge E, Stebbins, C. Erec

“…Many bacterial pathogens use a type III protein secretion system to deliver virulence effector proteins directly into the host cell cytosol, where they…”
Get full text

A Common Structural Motif in the Binding of Virulence Factors to Bacterial Secretion Chaperones by Lilic, Mirjana, Vujanac, Milos, Stebbins, C. Erec

“…Salmonella invasion protein A (SipA) is translocated into host cells by a type III secretion system (T3SS) and comprises two regions: one domain binds its…”
Get full text

Nanobody-mediated macromolecular crowding induces membrane fission and remodeling in the African trypanosome by Hempelmann, Alexander, Hartleb, Laura, van Straaten, Monique, Hashemi, Hamidreza, Zeelen, Johan P., Bongers, Kevin, Papavasiliou, F. Nina, Engstler, Markus, Stebbins, C. Erec, Jones, Nicola G.

“…The dense variant surface glycoprotein (VSG) coat of African trypanosomes represents the primary host-pathogen interface. Antigenic variation prevents clearing…”
Get full text

A structural classification of the variant surface glycoproteins of the African trypanosome by Dakovic, Sara, Zeelen, Johan P, Gkeka, Anastasia, Chandra, Monica, van Straaten, Monique, Foti, Konstantina, Zhong, Janet, Vlachou, Evi P, Aresta-Branco, Francisco, Verdi, Joseph P, Papavasiliou, F. Nina, Stebbins, C. Erec

“…Long-term immune evasion by the African trypanosome is achieved through repetitive cycles of surface protein replacement with antigenically distinct versions…”
Get full text

Identifying patterns of reported findings on long-term cardiac complications of COVID-19: a systematic review and meta-analysis by Guo, Boya, Zhao, Chenya, He, Mike Z, Senter, Camilla, Zhou, Zhenwei, Peng, Jin, Li, Song, Fitzpatrick, Annette L, Lindström, Sara, Stebbins, Rebecca C, Noppert, Grace A, Li, Chihua

“…Prior reviews synthesized findings of studies on long-term cardiac complications of COVID-19. However, the reporting and methodological quality of these…”
Get full text

Use of a bacteriophage lysin to identify a novel target for antimicrobial development by Schuch, Raymond, Pelzek, Adam J, Raz, Assaf, Euler, Chad W, Ryan, Patricia A, Winer, Benjamin Y, Farnsworth, Andrew, Bhaskaran, Shyam S, Stebbins, C Erec, Xu, Yong, Clifford, Adrienne, Bearss, David J, Vankayalapati, Hariprasad, Goldberg, Allan R, Fischetti, Vincent A

“…We identified an essential cell wall biosynthetic enzyme in Bacillus anthracis and an inhibitor thereof to which the organism did not spontaneously evolve…”
Get full text

Inhibitors of the Yersinia protein tyrosine phosphatase through high throughput and virtual screening approaches by Hu, Xin, Vujanac, Milos, Southall, Noel, Erec Stebbins, C.

“…A number of inhibitors of Yersinia protein tyrosine phosphatase YopH were identified using high throughput and virtual screening approaches. The bacterial…”
Get full text

Type III effector AvrPtoB requires intrinsic E3 ubiquitin ligase activity to suppress plant cell death and immunity by Abramovitch R.B, Janjusevic, R, Stebbins, C.E, Martin, G.B

“…Microbial pathogens of both plants and animals employ virulence factors that suppress the host immune response. The tomato pathogen Pseudomonas syringae…”
Get full text

Pathogenic bacteria target NEDD8-conjugated cullins to hijack host-cell signaling pathways by Jubelin, Grégory, Taieb, Frédéric, Duda, David M, Hsu, Yun, Samba-Louaka, Ascel, Nobe, Rika, Penary, Marie, Watrin, Claude, Nougayrède, Jean-Philippe, Schulman, Brenda A, Stebbins, C Erec, Oswald, Eric

“…The cycle inhibiting factors (Cif), produced by pathogenic bacteria isolated from vertebrates and invertebrates, belong to a family of molecules called…”
Get full text