Search Results - "Ste.Marie, Emma J."
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The Marine Neurotoxin Brevetoxin (PbTx-2) Inhibits Karenia brevis and Mammalian Thioredoxin Reductases by Targeting Different Residues
Published in Journal of natural products (Washington, D.C.) (26-11-2021)“…The brevetoxins, neurotoxins produced by Karenia brevis, the Florida red tide dinoflagellate, effect fish and wildlife mortalities and adverse public health…”
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Aggregation State of Synergistic Antimicrobial Peptides
Published in The journal of physical chemistry letters (05-11-2020)“…By integrating various simulation and experimental techniques, we discovered that antimicrobial peptides (AMPs) may achieve synergy at an optimal concentration…”
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Synthesis of alpha‐methyl selenocysteine and its utilization as a glutathione peroxidase mimic
Published in Journal of peptide science (01-06-2019)“…Selenocysteine (Sec) is the 21st amino acid in the genetic code where this amino acid is primarily involved in redox reactions in enzymes because of its high…”
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Selenium Drives a Transcriptional Adaptive Program to Block Ferroptosis and Treat Stroke
Published in Cell (16-05-2019)“…Ferroptosis, a non-apoptotic form of programmed cell death, is triggered by oxidative stress in cancer, heat stress in plants, and hemorrhagic stroke. A…”
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2,2′‐Dipyridyl diselenide: A chemoselective tool for cysteine deprotection and disulfide bond formation
Published in Journal of peptide science (01-03-2020)“…There are many examples of bioactive, disulfide‐rich peptides and proteins whose biological activity relies on proper disulfide connectivity. Regioselective…”
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Reduction of cysteine‐S‐protecting groups by triisopropylsilane
Published in Journal of peptide science (01-11-2018)“…Triisopropylsilane (TIS), a hindered hydrosilane, has long been utilized as a cation scavenger for the removal of amino acid protecting groups during peptide…”
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Facile removal of 4‐methoxybenzyl protecting group from selenocysteine
Published in Journal of peptide science (01-10-2019)“…Historically, methods to remove the 4‐methoxybenzyl (Mob)–protecting group from selenocysteine (Sec) in peptides have used harsh and toxic reagents. The use of…”
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