Search Results - "Stavale, Joao N."
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1
MR Cerebral Blood Volume Maps Correlated with Vascular Endothelial Growth Factor Expression and Tumor Grade in Nonenhancing Gliomas
Published in American Journal of Neuroradiology (01-04-2005)“…Relative cerebral blood volume (rCBV) measurements derived from perfusion-weighted imaging (PWI) may be useful to evaluate angiogenesis and preoperatively…”
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2
Stereotactic biopsy guidance in adults with supratentorial nonenhancing gliomas: role of perfusion-weighted magnetic resonance imaging
Published in Journal of neurosurgery (01-12-2004)“…The. diagnosis of low-grade glioma (LGG) cannot be based exclusively on conventional magnetic resonance (MR) imaging studies, and target selection for…”
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3
EGFRvIII Deletion Mutations in Pediatric High-Grade Glioma and Response to Targeted Therapy in Pediatric Glioma Cell Lines
Published in Clinical cancer research (15-09-2009)“…Purpose: The epidermal growth factor receptor (EGFR) is amplified and overexpressed in adult glioblastoma, with response to targeted inhibition dependent on…”
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4
Reproducibility of the NanoString 22-gene molecular subgroup assay for improved prognostic prediction of medulloblastoma
Published in Neuropathology (01-10-2018)“…Medulloblastoma is the most frequent malignant brain tumor in children. Four medulloblastoma molecular subgroups, MBSHH , MBWNT , MBGRP3 and MBGRP4 , have been…”
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5
Single nCounter assay for prediction of MYCN amplification and molecular classification of medulloblastomas: a multicentric study
Published in Journal of neuro-oncology (01-03-2022)“…Purpose Medulloblastoma is the most frequent pediatric malignant brain tumor, and is divided into four main subgroups: WNT, SHH, group 3, and group 4. MYCN…”
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Expression of GNAS, TP53, and PTEN Improves the Patient Prognostication in Sonic Hedgehog (SHH) Medulloblastoma Subgroup
Published in The Journal of molecular diagnostics : JMD (01-07-2020)“…Medulloblastoma (MB) is the most common malignant brain tumor in children. It is currently classified in four main molecular subgroups with different clinical…”
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7
Integrated Molecular Meta-Analysis of 1,000 Pediatric High-Grade and Diffuse Intrinsic Pontine Glioma
Published in Cancer cell (09-10-2017)“…We collated data from 157 unpublished cases of pediatric high-grade glioma and diffuse intrinsic pontine glioma and 20 publicly available datasets in an…”
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8
The involvement of the MAPK pathway in pilocytic astrocytomas
Published in Pathology, research and practice (01-04-2022)“…Pilocytic astrocytomas are the primary tumors most found in the first two decades of life, accounting for around 15% of all brain tumors. Research at the…”
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Pathophysiological evaluation of pilocytic astrocytoma in adults: Histopathological and immunohistochemical analysis
Published in Pathology, research and practice (01-08-2023)“…Pilocytic astrocytoma is a central nervous system tumor of slow growth, which represents 5 % of all gliomas and most often develops in the cerebellum (42–60…”
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10
Pilocytic astrocytoma in adults: Histopathological, immunohistochemical and molecular study with clinical association
Published in Pathology, research and practice (01-12-2023)“…Pilocytic astrocytoma is the most common primary CNS neoplasm in children and adolescents, rare after the first two decades of life. While some authors report…”
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11
Age-related changes in the N-methyl-D-aspartate receptor binding sites within the human basal ganglia
Published in Experimental neurology (01-10-2001)“…The present study examined the regional differences in dopamine transporter binding sites and NMDA receptor complex binding based on autoradiographic images…”
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Meningiomas: A review of general, histopathological, clinical and molecular characteristics
Published in Pathology, research and practice (01-07-2021)“…In this review, the main histological and molecular characteristics of meningiomas will be addressed, as well as the aspects most related to clinical…”
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13
Microsatellite instability in pediatric high grade glioma is associated with genomic profile and differential target gene inactivation
Published in PloS one (26-05-2011)“…High grade gliomas (HGG) are one of the leading causes of cancer-related deaths in children, and there is increasing evidence that pediatric HGG may harbor…”
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14
Metaphase and array comparative genomic hybridization: unique copy number changes and gene amplification of medulloblastomas in South America
Published in Cancer genetics and cytogenetics (01-10-2006)“…Tumors of the central nervous system are the second most frequent malignancy of childhood, accounting for the majority of cancer-related deaths in this age…”
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15
Grade I meningiomas with atypical characteristics: a worse prognosis
Published in Arquivos de neuro-psiquiatria (01-11-2018)“…The study reviewed the histology of cases of grade I meningiomas with spontaneous necrosis, grade I without necrosis and grade II meningiomas, to evaluate the…”
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16
Human papillomavirus DNA detection in male sexual partners of women with genital human papillomavirus infection
Published in Urology (Ridgewood, N.J.) (01-02-2005)“…To determine the prevalence of human papillomavirus (HPV) DNA in the male partners of HPV-infected women, assess the concordance of the viral group in the…”
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17
Ultrasonographic and morphological studies of the postmenopausal endometrium using unopposed estrogen replacement therapy with regular pause: a prospective preliminary study
Published in European journal of obstetrics & gynecology and reproductive biology (01-09-2001)“…Hormone replacement therapy with progestogen is known to have severe side effects or complications in certain patients. Objective: The goal of this study is to…”
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18
Gemistocytes in astrocytomas : Are they a significant prognostic factor?
Published in Journal of neuro-oncology (01-10-2006)“…Our aim was to retrospectively evaluate the influence of gemistocytic astrocytes, cellular proliferation indices, immunoexpression of proteins p53 and bcl-2 in…”
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19
Immunohistochemical expression of p16(INK4A) in normal uterine cervix, nonneoplastic epithelial lesions, and low-grade squamous intraepithelial lesions
Published in Journal of lower genital tract disease (01-04-2007)“…In this study, the authors analyzed the immunoexpression of p16 in high-risk human papillomavirus DNA-negative normal and nonneoplastic cervical epithelia, in…”
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20
Mild hypothermia reduces polymorphonuclear leukocytes infiltration in induced brain inflammation
Published in Arquivos de neuro-psiquiatria (01-09-2005)“…Over the last 50 years deep hypothermia (23 degrees C) has demonstrated to be an excellent neuroprotective agent in cerebral ischemic injury. Mild hypothermia…”
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