Search Results - "Staunton, Lisa"

Mass spectrometric characterization of the sarcoplasmic reticulum from rabbit skeletal muscle by on-membrane digestion by Staunton, Lisa, Ohlendieck, Kay

“…The sarcoplasmic reticulum from skeletal muscle constitutes an elaborate membrane system that contains a considerable number of integral and very large…”
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Proteomic Profiling of Mitochondrial Enzymes during Skeletal Muscle Aging by Staunton, Lisa, O'Connell, Kathleen, Ohlendieck, Kay

“…Mitochondria are of central importance for energy generation in skeletal muscles. Expression changes or functional alterations in mitochondrial enzymes play a…”
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Mass spectrometry-based proteomic analysis of middle-aged vs. aged vastus lateralis reveals increased levels of carbonic anhydrase isoform 3 in senescent human skeletal muscle by STAUNTON, LISA, ZWEYER, MARGIT, SWANDULLA, DIETER, OHLENDIECK, KAY

“…The age-related loss of skeletal muscle mass and associated progressive decline in contractile strength is a serious pathophysiological issue in the elderly…”
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Proteomic analysis of muscle affected by motor neuron degeneration: The wobbler mouse model of amyotrophic lateral sclerosis by Staunton, Lisa, Jockusch, Harald, Ohlendieck, Kay

“…► Proteomic analysis of wobbler mouse model of amyotrophic lateral sclerosis confirms atrophy-related changes in skeletal muscle. ► Fluorescence difference…”
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Phosphoproteomic analysis of aged skeletal muscle by Gannon, Joan, Staunton, Lisa, O'Connell, Kathleen, Doran, Philip, Ohlendieck, Kay

“…One of the most important post-translational modifications is represented by phosphorylation on tyrosine, threonine and serine residues. Since abnormal…”
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DIGE analysis of rat skeletal muscle proteins using nonionic detergent phase extraction of young adult versus aged gastrocnemius tissue by Donoghue, Pamela, Staunton, Lisa, Mullen, Edel, Manning, Gwen, Ohlendieck, Kay

“…Contractile weakness and loss of muscle mass are critical features of the aging process in mammalians. Age-related fibre wasting has a profound effect on…”
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Pathoproteomics of testicular tissue deficient in the GARP component VPS54: The wobbler mouse model of globozoospermia by Jockusch, Harald, Holland, Ashling, Staunton, Lisa, Schmitt-John, Thomas, Heimann, Peter, Dowling, Paul, Ohlendieck, Kay

“…In human globozoospermia, round‐headed spermatozoa lack an acrosome and therefore cannot properly interact with oocytes. In the wobbler (WR) mouse, an L967Q…”
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Identification of Differentially Expressed Proteins from Smokeless Tobacco Addicted Patients Suffering from Oral Squamous Cell Carcinoma by Malik, Uzma Urooj, Siddiqui, Imtiaz Ather, Ilyas, Amber, Hashim, Zehra, Staunton, Lisa, Kwasnik, Anna, Pennington, Stephen R., Zarina, Shamshad

“…Oral squamous cell carcinoma (OSCC) is the eight most common malignancy worldwide with an incidence rate of 40% in south-east Asia. Lack of effective…”
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Pathology-Driven Comprehensive Proteomic Profiling of the Prostate Cancer Tumor Microenvironment by Staunton, Lisa, Tonry, Claire, Lis, Rosina, Espina, Virginia, Liotta, Lance, Inzitari, Rosanna, Bowden, Michaela, Fabre, Aurelie, O'Leary, John, Finn, Stephen P, Loda, Massimo, Pennington, Stephen R

“…Prostate cancer is the second most common cancer in men worldwide. Gleason grading is an important predictor of prostate cancer outcomes and is influential in…”
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Identification of secondary effects of hyperexcitability by proteomic profiling of myotonic mouse muscle by Staunton, Lisa, Jockusch, Harald, Wiegand, Christiane, Albrecht, Timo, Ohlendieck, Kay

“…Myotonia is a symptom of various genetic and acquired skeletal muscular disorders and is characterized by hyperexcitability of the sarcolemma. Here, we have…”
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Discovery and Longitudinal Evaluation of Candidate Protein Biomarkers for Disease Recurrence in Prostate Cancer by Tonry, Claire L, Doherty, Darren, O’Shea, Carmel, Morrissey, Brian, Staunton, Lisa, Flatley, Brian, Shannon, Aoife, Armstrong, John, Pennington, Stephen R

“…When compared with hormonal therapy alone, treatment with combined hormone and radiation therapy (CHRT) gives improved disease-specific survival outcomes for…”
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Development of a label-free LC-MS/MS strategy to approach the identification of candidate protein biomarkers of disease recurrence in prostate cancer patients in a clinical trial of combined hormone and radiation therapy by Morrissey, Brian, O'Shea, Carmel, Armstrong, John, Rooney, Cathy, Staunton, Lisa, Sheehan, Martina, Shannon, Aoife M., Pennington, Stephen R.

“…Purpose Combined hormone and radiation therapy (CHRT) is one of the principle curative regimes for localised prostate cancer (PCa). Following treatment, many…”
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