Search Results - "Stauderman, Ken"
-
1
Inhibitors of ORAI1 Prevent Cytosolic Calcium-Associated Injury of Human Pancreatic Acinar Cells and Acute Pancreatitis in 3 Mouse Models
Published in Gastroenterology (New York, N.Y. 1943) (01-08-2015)“…Background & Aims Sustained activation of the cytosolic calcium concentration induces injury to pancreatic acinar cells and necrosis. The calcium…”
Get full text
Journal Article -
2
Human autoantibodies specific for the α1A calcium channel subunit reduce both P-type and Q-type calcium currents in cerebellar neurons
Published in Proceedings of the National Academy of Sciences - PNAS (07-07-1998)“…The pharmacological properties of voltage-dependent calcium channel (VDCC) subtypes appear mainly to be determined by the α 1 pore-forming subunit but, whether…”
Get full text
Journal Article -
3
Abstract WP134: Calcium Release-activated Calcium Channel Inhibition Improves Neurological Outcome and Suppresses Inflammation in Female Mice Following Cerebral Ischemic Injury
Published in Stroke (1970) (01-02-2019)“…Abstract only Purpose: Calcium release-activated calcium (CRAC) channels activate microglia via store-operated Ca 2+ entry. We previously reported that the…”
Get full text
Journal Article -
4
Abstract TP255: Calcium Release-activated Calcium Channel Inhibition Protects Against Inflammation in Ischemic Stroke
Published in Stroke (1970) (22-01-2018)“…Abstract only Purpose: Inflammatory responses after ischemic stroke contribute to worsening of ischemic brain injury. Calcium release-activated calcium (CRAC)…”
Get full text
Journal Article -
5
Abstract TP272: Calcium Release-activated Calcium (CRAC) Channel Inhibition Protects Against Brain Injury and Neuronal Death Induced by Activated Microglia
Published in Stroke (1970) (01-02-2017)“…Abstract only Inflammatory responses following ischemia can worsen neurological outcome, and represent a potential target for therapeutic intervention…”
Get full text
Journal Article -
6
Combination of the CRAC Channel Inhibitor CM4620 and Galactose as a Potential Therapy for Acute Pancreatitis
Published in Function (Oxford, England) (11-07-2024)“…Acute pancreatitis (AP) is a life-threatening inflammatory disease with no specific therapy. Excessive cytoplasmic Ca2+ elevation and intracellular ATP…”
Get full text
Journal Article -
7
Human Autoantibodies Specific for the α1ACalcium Channel Subunit Reduce Both P-Type and Q-Type Calcium Currents in Cerebellar Neurons
Published in Proceedings of the National Academy of Sciences - PNAS (07-07-1998)“…The pharmacological properties of voltage-dependent calcium channel (VDCC) subtypes appear mainly to be determined by the α1pore-forming subunit but, whether…”
Get full text
Journal Article -
8
Human autoantibodies specific for the α 1A calcium channel subunit reduce both P-type and Q-type calcium currents in cerebellar neurons
Published in Proceedings of the National Academy of Sciences - PNAS (07-07-1998)“…The pharmacological properties of voltage-dependent calcium channel (VDCC) subtypes appear mainly to be determined by the α 1 pore-forming subunit but, whether…”
Get full text
Journal Article -
9
The time and space machine: continuous measurement of drug-induced behavior patterns in the rat
Published in Psychopharmacology (01-01-1983)“…Because of the increasing demand for refined techniques to record drug-induced motoric changes, we designed and evaluated a computer monitoring system with…”
Get full text
Journal Article