Attachment of histidine, histamine and urocanic acid to resins of the trityl-type

Histidine, histamine and urocanic acid were attached through the N im-function on resins of the trityl type. The conditions of the cleavage of these derivatives from the resin were determined. Resin bound histamine was used in the solid phase synthesis of carcinine. Suitably protected imidazolyl-com...

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Bibliographic Details
Published in:Tetrahedron letters Vol. 40; no. 14; pp. 2825 - 2828
Main Authors: Eleftheriou, Sofia, Gatos, Dimitrios, Panagopoulos, Antonis, Stathopoulos, Stephanos, Barlos, Kleomenis
Format: Journal Article
Language:English
Published: Elsevier Ltd 02-04-1999
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Summary:Histidine, histamine and urocanic acid were attached through the N im-function on resins of the trityl type. The conditions of the cleavage of these derivatives from the resin were determined. Resin bound histamine was used in the solid phase synthesis of carcinine. Suitably protected imidazolyl-compounds are attached in good yield onto resins of the trityl-type.
ISSN:0040-4039
1873-3581
DOI:10.1016/S0040-4039(99)00270-1