Search Results - "Stathopoulos, George P"
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1
The role of Ki-67 in the proliferation and prognosis of breast cancer molecular classification subtypes
Published in Anti-cancer drugs (01-09-2014)“…The Ki-67 antigen was identified in the early steps of polymerase I-dependent ribosomal RNA synthesis. Although it seems that this protein has an important…”
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2
Liposomal Oxaliplatin in the Treatment of Advanced Cancer: A Phase I Study
Published in Anticancer research (01-03-2006)“…Background: Lipoxal is a liposomal oxaliplatin, which reduces the cytotoxic agent's adverse reactions without reducing effectiveness. Our objectives were to…”
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3
Liposomal cisplatin: a new cisplatin formulation
Published in Anti-cancer drugs (01-09-2010)“…Over the last three decades, cisplatin has been one of the most effective cytotoxic agents, but its administration has been hindered by its nephrotoxicity,…”
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4
Decreased Plasma Ghrelin Levels in Patients with Advanced Cancer and Weight Loss in Comparison to Healthy Individuals
Published in Anticancer research (01-10-2009)“…Background: Ghrelin is a growth hormone-releasing acylated peptide found to be an appetite stimulant and low levels of it are detected in cachexia. The aim of…”
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5
Mouse p53-deficient cancer models as platforms for obtaining genomic predictors of human cancer clinical outcomes
Published in PloS one (07-08-2012)“…Mutations in the TP53 gene are very common in human cancers, and are associated with poor clinical outcome. Transgenic mouse models lacking the Trp53 gene or…”
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6
Present Treatment and Future Expectations in Advanced Pancreatic Cancer
Published in Anticancer research (01-03-2008)“…Advanced or metastatic pancreatic cancer is an incurable disease. The main treatment is chemotherapy with cytotoxic agents. On the basis of our experience in…”
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7
Phase II study of bevacizumab plus irinotecan on the treatment of relapsed resistant small cell lung cancer
Published in Cancer chemotherapy and pharmacology (01-04-2016)“…Purpose This phase II study investigates the efficacy and safety of DNA topoisomerase I inhibitor irinotecan plus bevacizumab a monoclonal antibody against…”
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8
Bone metastasis in breast cancer is treated by high-dose tamoxifen
Published in Journal of B.U. ON. (01-07-2016)“…Bone metastases in breast cancer are quite common, and some patients may have no other site of metastasis. An effective treatment is often endocrine agents…”
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9
A retrospective open-label uncontrolled study of Epoetin zeta on the treatment of chemotherapy-induced anemia in solid tumors
Published in Journal of cancer research and clinical oncology (01-04-2017)“…Purpose This is a single-center uncontrolled retrospective study to evaluate the efficacy and safety of the biosimilar epoetin zeta after approval in…”
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10
Postoperative dose-dense sequential versus concomitant administration of epirubicin and paclitaxel in patients with node-positive breast cancer: 5-year results of the Hellenic Cooperative Oncology Group HE 10/00 phase III Trial
Published in Breast cancer research and treatment (01-04-2012)“…To explore the impact of dose intensity (DI) in the adjuvant setting of breast cancer, a randomized phase III trial was conducted comparing postoperative…”
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11
Therapeutic Administration of Pegfilgrastim Instead of Prophylactic Use
Published in Anticancer research (01-05-2005)“…Objectives: Pegfilgrastim is a new growth factor which can be administered subcutaneously once (versus multiple doses for days) on the day neutropenia occurs…”
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12
Subdivision of molecularly-classified groups by new gene signatures in breast cancer patients
Published in Oncology reports (01-12-2012)“…Gene expression patterns as well as gene interactions are under investigation for their involvement in tumour heterogeneity. The molecular classification of…”
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13
Mesothelioma: Treatment and Survival of a Patient Population and Review of the Literature
Published in Anticancer research (01-09-2005)“…Background: Our purpose was to evaluate the survival of patients with pleural and intraperitoneal malignant mesothelioma and, particularly, to estimate the…”
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14
Phase II Study of Cisplatin-combined Schedules as Second-line Chemotherapy in Patients with Non-Small Cell Lung Cancer
Published in Anticancer research (01-07-2005)“…Background: The aim of this study was to evaluate the effectiveness of cisplatin- (CDDP) combined chemotherapy in non-cisplatin pretreated patients with…”
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15
Predictive value of D-dimer plasma levels in response and progressive disease in patients with lung cancer
Published in Lung cancer (Amsterdam, Netherlands) (01-08-2006)“…Patients with cancer may present with one or more circulatory markers of haemostatic activation which may be associated with tumor growth and cancer cell…”
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16
Pharmacokinetics and adverse reactions of a new liposomal cisplatin (Lipoplatin): phase I study
Published in Oncology reports (01-04-2005)“…Lipoplatin, a new liposomal cisplatin formulation, is formed from cisplatin and liposomes composed of dipalmitoyl phosphatidyl glycerol (DPPG), soy…”
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17
A multicenter phase II study of docetaxel in combination with gefitinib in gemcitabine-pretreated patients with advanced/metastatic pancreatic cancer
Published in Oncology (01-01-2006)“…To evaluate the efficacy and tolerance of the docetaxel/gefitinib combination as second-line treatment in patients with advanced pancreatic cancer. Twenty-six…”
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18
Liposomal cisplatin combined with gemcitabine in pretreated advanced pancreatic cancer patients : A phase I-II study
Published in Oncology reports (01-05-2006)“…The present trial is a phase I-II study based on a new liposomal cisplatin (lipoplatin). Previous preclinical and clinical data (phase I pharmacokinetics) led…”
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19
Pemetrexed combined with paclitaxel in patients with advanced or metastatic non-small-cell lung cancer: A phase I-II trial
Published in Lung cancer (Amsterdam, Netherlands) (01-07-2007)“…Summary Pemetrexed, a novel multi-targeted agent established for the treatment of mesothelioma, has been under investigation for other malignancies, and in…”
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20
Topotecan and pegylated liposomal doxorubicin combination as palliative treatment in patients with pretreated advanced malignant pleural mesothelioma
Published in International journal of clinical pharmacology and therapeutics (01-07-2012)“…Malignant pleural mesothelioma (MPM) is an aggressive disease with poor or modest responses to chemotherapy and dismal prognosis. In most of the cases the…”
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