Search Results - "Stass, S A"
-
1
Downregulation of miR-486-5p contributes to tumor progression and metastasis by targeting protumorigenic ARHGAP5 in lung cancer
Published in Oncogene (27-02-2014)“…We have previously shown that miR-486-5p is one of the most downregulated micro RNAs in lung cancer. The objective of the study was to investigate the role of…”
Get full text
Journal Article -
2
Identification of putative oncogenes in lung adenocarcinoma by a comprehensive functional genomic approach
Published in Oncogene (27-04-2006)“…Amplification and overexpression of putative oncogenes confer growth advantages for tumor development. We used a functional genomic approach that integrated…”
Get full text
Journal Article -
3
Targeted disruption of Aurora A causes abnormal mitotic spindle assembly, chromosome misalignment and embryonic lethality
Published in Oncogene (03-07-2008)“…Aurora A (also known as STK15/BTAK in humans), a putative oncoprotein naturally overexpressed in many human cancers, is a member of the conserved Aurora…”
Get full text
Journal Article -
4
Co-polymer of histidine and lysine markedly enhances transfection efficiency of liposomes
Published in Gene therapy (01-10-2000)“…Development of nonviral delivery systems is progressing toward a transfection efficiency sufficient to affect metabolic and neoplastic diseases in humans…”
Get full text
Journal Article -
5
Liposomes complexed to plasmids encoding angiostatin and endostatin inhibit breast cancer in nude mice
Published in Cancer research (Chicago, Ill.) (15-07-1999)“…Gene therapy transfer of angiostatin and endostatin represents an alternative method of delivering angiogenic polypeptide inhibitors. We examined whether…”
Get full text
Journal Article -
6
The human MDM-2 oncogene is overexpressed in leukemias
Published in Blood (01-11-1993)“…The human homologue of the mouse double minute 2 (MDM-2) gene codes for a cellular protein that forms a complex with the mutant and wild-type p53 protein and…”
Get full text
Journal Article -
7
Isochromosome 7q: the primary cytogenetic abnormality in hepatosplenic γδ T cell lymphoma
Published in Leukemia (01-08-1997)“…Malignant lymphomas often have complex, nonrandom chromosomal abnormalities. Hepatosplenic γδ T cell lymphoma (γTCL) is an unusual post-thymic T cell lymphoma…”
Get full text
Journal Article -
8
Parenteral gene therapy with p53 inhibits human breast tumors in vivo through a bystander mechanism without evidence of toxicity
Published in Human gene therapy (20-01-1997)“…Mutations of the p53 tumor suppressor gene are the most frequently observed genetic lesion in human cancer. Previously, we found that multiple intravenous…”
Get more information
Journal Article -
9
Characterization of a fusion cDNA (RARA/myl) transcribed from the t(15;17) translocation breakpoint in acute promyelocytic leukemia
Published in Molecular and Cellular Biology (01-02-1992)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text
Journal Article -
10
Detection of Minimal Residual Cells Carrying the t(14;18) by DNA Sequence Amplification
Published in Science (American Association for the Advancement of Science) (10-07-1987)“…By means of the polymerase chain reaction (PCR) technique, DNA sequences were amplified that flank the crossover sites of a characteristic chromosomal…”
Get full text
Journal Article -
11
Developing dendritic cell polynucleotide vaccination for prostate cancer immunotherapy
Published in Journal of biotechnology (20-08-1999)“…Immunotherapy has been successfully used to treat some human malignancies, principally melanoma and renal cell carcinoma. Genetic-based cancer immunotherapies…”
Get full text
Journal Article Conference Proceeding -
12
RAS mutations are rare events in Philadelphia chromosome-negative/bcr gene rearrangement-negative chronic myelogenous leukemia, but are prevalent in chronic myelomonocytic leukemia
Published in Blood (15-09-1990)“…Previous reports have indicated that mutations of the RAS oncogenes are not associated with the chronic phase of Philadelphia chromosome-positive chronic…”
Get full text
Journal Article -
13
Detection of Minimal Residual bcr/abl Transcripts by a Modified Polymerase Chain Reaction
Published in Blood (01-09-1988)“…The Philadelphia (Ph1) chromosome in chronic myelogenous leukemia (CML) involves reciprocal translocation of the bcr gene and the c-abl oncogene. The fused…”
Get full text
Journal Article -
14
Regulation of the expression of annexin VIII in acute promyelocytic leukemia
Published in Blood (01-07-1994)“…Annexin VIII is a calcium-dependent phospholipid-binding protein previously identified as a blood anticoagulant based on in vitro studies. However, the…”
Get full text
Journal Article -
15
Gene therapy with p53 and a fragment of thrombospondin I inhibits human breast cancer in vivo
Published in Molecular genetics and metabolism (01-02-1998)“…We recently reported that a p53 encoding plasmid (BAP-p53) complexed to liposomes administered intravenously markedly attenuates the growth of a malignant…”
Get full text
Journal Article -
16
Oncogenes and tumor suppressor genes: therapeutic implications
Published in Clinical cancer research (01-12-1997)“…Genetic instability is a hallmark of cancer. Alterations in DNA through mutations, deletions, and translocations affect genes that are fundamental to normal…”
Get full text
Journal Article -
17
Expression of AML1-ETO fusion transcripts and detection of minimal residual disease in t(8;21)-positive acute myeloid leukemia
Published in Oncogene (01-04-1993)“…The t(8;21) translocation breakpoint, which is observed in acute myeloid leukemia (AML), has recently been cloned and a fusion transcript identified. We have…”
Get more information
Journal Article -
18
HL-60 Cell Line Was Derived From a Patient With FAB-M2 and Not FAB-M3
Published in Blood (01-01-1988)“…The leukemia from which the human cell line HL-60 was derived was classified in 1976 as acute progranulocytic leukemia (APL), although it was recognized to…”
Get full text
Journal Article -
19
Molecular Heterogeneity in Acute Leukemia Lineage Switch
Published in Blood (01-11-1989)“…Six cases of acute leukemia that underwent lineage switch from acute lymphocytic leukemia to acute myelogenous leukemia are reported. The mean age of the…”
Get full text
Journal Article -
20
Histologically discordant lymphomas with B-cell and T-cell components
Published in American journal of clinical pathology (01-09-1997)“…We describe the clinical, histologic, immunophenotypic, and genotypic features of five cases of histologically discordant lymphomas with B-cell and T-cell…”
Get full text
Conference Proceeding Journal Article