Search Results - "Stass, Robert"

Multifunctional human monoclonal antibody combination mediates protection against Rift Valley fever virus at low doses by Chapman, Nathaniel S., Hulswit, Ruben J. G., Westover, Jonna L. B., Stass, Robert, Paesen, Guido C., Binshtein, Elad, Reidy, Joseph X., Engdahl, Taylor B., Handal, Laura S., Flores, Alejandra, Gowen, Brian B., Bowden, Thomas A., Crowe, James E.

“…The zoonotic Rift Valley fever virus (RVFV) can cause severe disease in humans and has pandemic potential, yet no approved vaccine or therapy exists. Here we…”
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Structural Basis for a Neutralizing Antibody Response Elicited by a Recombinant Hantaan Virus Gn Immunogen by Rissanen, Ilona, Krumm, Stefanie A, Stass, Robert, Whitaker, Annalis, Voss, James E, Bruce, Emily A, Rothenberger, Sylvia, Kunz, Stefan, Burton, Dennis R, Huiskonen, Juha T, Botten, Jason W, Bowden, Thomas A, Doores, Katie J

“…Hantaviruses are a group of emerging pathogens capable of causing severe disease upon zoonotic transmission to humans. The mature hantavirus surface presents…”
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Molecular rationale for antibody-mediated targeting of the hantavirus fusion glycoprotein by Rissanen, Ilona, Stass, Robert, Krumm, Stefanie A, Seow, Jeffrey, Hulswit, Ruben Jg, Paesen, Guido C, Hepojoki, Jussi, Vapalahti, Olli, Lundkvist, Åke, Reynard, Olivier, Volchkov, Viktor, Doores, Katie J, Huiskonen, Juha T, Bowden, Thomas A

“…The intricate lattice of Gn and Gc glycoprotein spike complexes on the hantavirus envelope facilitates host-cell entry and is the primary target of the…”
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Beyond structures of highly symmetric purified viral capsids by cryo-EM by Stass, Robert, Ilca, Serban L, Huiskonen, Juha T

“…•Single-particle averaging has evolved to determine high resolution structures of large icosahedral viruses and viral genomes.•Sub-tomogram averaging continues…”
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The Hantavirus Surface Glycoprotein Lattice and Its Fusion Control Mechanism by Serris, Alexandra, Stass, Robert, Bignon, Eduardo A., Muena, Nicolás A., Manuguerra, Jean-Claude, Jangra, Rohit K., Li, Sai, Chandran, Kartik, Tischler, Nicole D., Huiskonen, Juha T., Rey, Felix A., Guardado-Calvo, Pablo

“…Hantaviruses are rodent-borne viruses causing serious zoonotic outbreaks worldwide for which no treatment is available. Hantavirus particles are pleomorphic…”
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Structural Transitions of the Conserved and Metastable Hantaviral Glycoprotein Envelope by Rissanen, Ilona, Stass, Robert, Zeltina, Antra, Li, Sai, Hepojoki, Jussi, Harlos, Karl, Gilbert, Robert J C, Huiskonen, Juha T, Bowden, Thomas A

“…Hantaviruses are zoonotic pathogens that cause severe hemorrhagic fever and pulmonary syndrome. The outer membrane of the hantavirus envelope displays a…”
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Structures of enveloped virions determined by cryogenic electron microscopy and tomography by Stass, Robert, Ng, Weng M, Kim, Young Chan, Huiskonen, Juha T

“…Enveloped viruses enclose their genomes inside a lipid bilayer which is decorated by membrane proteins that mediate virus entry. These viruses display a wide…”
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Structural Determinants of Bunyavirus Entry and Neutralisation by Stass, Robert

“…The order Bunyavirales is comprised of numerous emerging zoonotic pathogens which present a global threat to human health. Many bunyaviruses are arboviruses…”
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Expression and purification of tau protein and its frontotemporal dementia variants using a cleavable histidine tag by Karikari, Thomas K., Turner, Alexandra, Stass, Robert, Lee, Leonie C.Y., Wilson, Bethany, Nagel, David A., Hill, Eric J., Moffat, Kevin G.

“…Recombinant tau protein is widely used to study the biochemical, cellular and pathological aspects of tauopathies, including Alzheimer's disease and…”
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Mechanistic basis for potent neutralization of Sin Nombre hantavirus by a human monoclonal antibody by Stass, Robert, Engdahl, Taylor B., Chapman, Nathaniel S., Wolters, Rachael M., Handal, Laura S., Diaz, Summer M., Crowe, James E., Bowden, Thomas A.

“…Rodent-borne hantaviruses are prevalent worldwide and upon spillover to human populations, cause severe disease for which no specific treatment is available. A…”
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