Search Results - "Stasiak, Alicja Z."

Cooperation of breast cancer proteins PALB2 and piccolo BRCA2 in stimulating homologous recombination by Masson, Jean-Yves, Cai, Hong, Coulombe, Yan, Stasiak, Andrzej, Dion-Côté, Anne-Marie, Launay, Hélène, Xia, Bing, Buisson, Rémi, Stasiak, Alicja Z

“…Tumor suppressor PALB2 is known to interact with BRCA2 and promote homologous recombination in vivo . Now PALB2's activities have been studied, together with a…”
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The Fanconi Anemia Protein FANCM Can Promote Branch Migration of Holliday Junctions and Replication Forks by Gari, Kerstin, Décaillet, Chantal, Stasiak, Alicja Z., Stasiak, Andrzej, Constantinou, Angelos

“…Fanconi anemia (FA) is a genetically heterogeneous cancer-prone disorder associated with chromosomal instability and cellular hypersensitivity to DNA…”
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A Histone-Fold Complex and FANCM Form a Conserved DNA-Remodeling Complex to Maintain Genome Stability by Yan, Zhijiang, Delannoy, Mathieu, Ling, Chen, Daee, Danielle, Osman, Fekret, Muniandy, Parameswary A., Shen, Xi, Oostra, Anneke B., Du, Hansen, Steltenpool, Jurgen, Lin, Ti, Schuster, Beatrice, Décaillet, Chantal, Stasiak, Andrzej, Stasiak, Alicja Z., Stone, Stacie, Hoatlin, Maureen E., Schindler, Detlev, Woodcock, Christopher L., Joenje, Hans, Sen, Ranjan, de Winter, Johan P., Li, Lei, Seidman, Michael M., Whitby, Matthew C., Myung, Kyungjae, Constantinou, Angelos, Wang, Weidong

“…FANCM remodels branched DNA structures and plays essential roles in the cellular response to DNA replication stress. Here, we show that FANCM forms a conserved…”
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Role of BRCA2 in Control of the RAD51 Recombination and DNA Repair Protein by Davies, Adelina A, Masson, Jean-Yves, McIlwraith, Michael J, Stasiak, Alicja Z, Stasiak, Andrzej, Venkitaraman, Ashok R, West, Stephen C

“…Individuals carrying BRCA2 mutations are predisposed to breast and ovarian cancers. Here, we show that BRCA2 plays a dual role in regulating the actions of…”
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Functional and Structural Basis for a Bacteriophage Homolog of Human RAD52 by Ploquin, Mickaël, Bransi, Ali, Paquet, Eric R., Stasiak, Alicja Z., Stasiak, Andrzej, Yu, Xiong, Cieslinska, Anna M., Egelman, Edward H., Moineau, Sylvain, Masson, Jean-Yves

“…In eukaryotes, homologous recombination proteins such as RAD51 and RAD52 play crucial roles in DNA repair and genome stability. Human RAD52 is a member of a…”
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ParA2, a Vibrio cholerae chromosome partitioning protein, forms left-handed helical filaments on DNA by Hui, Monica P, Galkin, Vitold E, Yu, Xiong, Stasiak, Alicja Z, Stasiak, Andrzej, Waldor, Matthew K, Egelman, Edward H

“…Most bacterial chromosomes contain homologs of plasmid partitioning (par) loci. These loci encode ATPases called ParA that are thought to contribute to the…”
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Probing Rad51-DNA interactions by changing DNA twist by Atwell, Scott, Disseau, Ludovic, Stasiak, Alicja Z, Stasiak, Andrzej, Renodon-Cornière, Axelle, Takahashi, Masayuki, Viovy, Jean-Louis, Cappello, Giovanni

“…In eukaryotes, Rad51 protein is responsible for the recombinational repair of double-strand DNA breaks. Rad51 monomers cooperatively assemble on…”
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MRE11-RAD50-NBS1 is a critical regulator of FANCD2 stability and function during DNA double-strand break repair by Roques, Céline, Coulombe, Yan, Delannoy, Mathieu, Vignard, Julien, Grossi, Simona, Brodeur, Isabelle, Rodrigue, Amélie, Gautier, Jean, Stasiak, Alicja Z, Stasiak, Andrzej, Constantinou, Angelos, Masson, Jean-Yves

“…Monoubiquitination of the Fanconi anaemia protein FANCD2 is a key event leading to repair of interstrand cross‐links. It was reported earlier that FANCD2…”
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Design of Potent Inhibitors of Human RAD51 Recombinase Based on BRC Motifs of BRCA2 Protein: Modeling and Experimental Validation of a Chimera Peptide by Nomme, Julian, Renodon-Cornière, Axelle, Asanomi, Yuya, Sakaguchi, Kazuyasu, Stasiak, Alicja Z, Stasiak, Andrzej, Norden, Bengt, Tran, Vinh, Takahashi, Masayuki

“…We have previously shown that a 28-amino acid peptide derived from the BRC4 motif of BRCA2 tumor suppressor inhibits selectively human RAD51 recombinase…”
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Binding of double-strand breaks in DNA by human Rad52 protein by West, Stephen C, Dyck, Eric Van, Stasiak, Alicja Z, Stasiak, Andrzej

“…Double-strand breaks (DSBs) in DNA are caused by ionizing radiation. These chromosomal breaks can kill the cell unless repaired efficiently, and inefficient or…”
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Activation of Human Meiosis-specific Recombinase Dmc1 by Ca2 by Bugreev, Dmitry V., Golub, Efim I., Stasiak, Alicja Z., Stasiak, Andrzej, Mazin, Alexander V.

“…Rad51 and its meiotic homolog Dmc1 are key proteins of homologous recombination in eukaryotes. These proteins form nucleoprotein complexes on single-stranded…”
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Fission Yeast Rad51 and Dmc1, Two Efficient DNA Recombinases Forming Helical Nucleoprotein Filaments by Sauvageau, Synthia, Stasiak, Alicja Z., Banville, Isabelle, Ploquin, Mickaël, Stasiak, Andrzej, Masson, Jean-Yves

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Reconstitution of the strand invasion step of double-strand break repair using human Rad51 Rad52 and RPA proteins by McIlwraith, Michael J, Van Dyck, Eric, Masson, Jean-Yves, Stasiak, Alicja Z, Stasiak, Andrzej, West, Stephen C

“…The human Rad51 recombinase is essential for the repair of double-strand breaks in DNA that occur in somatic cells after exposure to ionising irradiation, or…”
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Conformational Changes Modulate the Activity of Human RAD51 Protein by Liu, Yilun, Stasiak, Alicja Z, Masson, Jean-Yves, McIlwraith, Michael J, Stasiak, Andrzej, West, Stephen C

“…Homologous recombination provides a major pathway for the repair of DNA double-strand breaks in mammalian cells. Defects in homologous recombination can lead…”
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Visualization of recombination intermediates produced by RAD52-mediated single-strand annealing by Van Dyck, Eric, Stasiak, Alicja Z, Stasiak, Andrzej, West, Stephen C

“…Double‐strand breaks (DSBs) occur frequently during DNA replication. They are also caused by ionizing radiation, chemical damage or as part of the series of…”
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RDM1, a Novel RNA Recognition Motif (RRM)-containing Protein Involved in the Cell Response to Cisplatin in Vertebrates by Hamimes, Samia, Arakawa, Hiroshi, Stasiak, Alicja Z., Kierzek, Andrzej M., Hirano, Seiki, Yang, Yun-Gui, Takata, Minoru, Stasiak, Andrzej, Buerstedde, Jean-Marie, Van Dyck, Eric

“…A variety of cellular proteins has the ability to recognize DNA lesions induced by the anti-cancer drug cisplatin, with diverse consequences on their repair…”
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Saccharomyces cerevisiae Dmc1 and Rad51 Proteins Preferentially Function with Tid1 and Rad54 Proteins, Respectively, to Promote DNA Strand Invasion during Genetic Recombination by Nimonkar, Amitabh V., Dombrowski, Christopher C., Siino, Joseph S., Stasiak, Alicja Z., Stasiak, Andrzej, Kowalczykowski, Stephen C.

“…The Saccharomyces cerevisiae Dmc1 and Tid1 proteins are required for the pairing of homologous chromosomes during meiotic recombination. This pairing is the…”
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FtsK Is a DNA Motor Protein that Activates Chromosome Dimer Resolution by Switching the Catalytic State of the XerC and XerD Recombinases by Aussel, Laurent, Barre, François-Xavier, Aroyo, Mira, Stasiak, Andrzej, Stasiak, Alicja Z, Sherratt, David

“…FtsK acts at the bacterial division septum to couple chromosome segregation with cell division. We demonstrate that a truncated FtsK derivative, FtsK 50C, uses…”
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Identification and purification of two distinct complexes containing the five RAD51 paralogs by Masson, J Y, Tarsounas, M C, Stasiak, A Z, Stasiak, A, Shah, R, McIlwraith, M J, Benson, F E, West, S C

“…Cells defective in any of the RAD51 paralogs (RAD51B, RAD51C, RAD51D, XRCC2, and XRCC3) are sensitive to DNA cross-linking agents and to ionizing radiation…”
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Binding of double-strand breaks in DNA by human Rad52 protein by Van Dyck, Eric, Stasiak, Alicja Z., Stasiak, Andrzej, West, Stephen C.

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