Search Results - "Stashi, Erin"

Coactivator-Dependent Oscillation of Chromatin Accessibility Dictates Circadian Gene Amplitude via REV-ERB Loading by Zhu, Bokai, Gates, Leah A., Stashi, Erin, Dasgupta, Subhamoy, Gonzales, Naomi, Dean, Adam, Dacso, Clifford C., York, Brian, O’Malley, Bert W.

“…A central mechanism for controlling circadian gene amplitude remains elusive. We present evidence for a “facilitated repression (FR)” model that functions as…”
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Coactivator SRC-2-dependent metabolic reprogramming mediates prostate cancer survival and metastasis by Dasgupta, Subhamoy, Putluri, Nagireddy, Long, Weiwen, Zhang, Bin, Wang, Jianghua, Kaushik, Akash K, Arnold, James M, Bhowmik, Salil K, Stashi, Erin, Brennan, Christine A, Rajapakshe, Kimal, Coarfa, Cristian, Mitsiades, Nicholas, Ittmann, Michael M, Chinnaiyan, Arul M, Sreekumar, Arun, O'Malley, Bert W

“…Metabolic pathway reprogramming is a hallmark of cancer cell growth and survival and supports the anabolic and energetic demands of these rapidly dividing…”
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SRC-2 Is an Essential Coactivator for Orchestrating Metabolism and Circadian Rhythm by Stashi, Erin, Lanz, Rainer B., Mao, Jianqiang, Michailidis, George, Zhu, Bokai, Kettner, Nicole M., Putluri, Nagireddy, Reineke, Erin L., Reineke, Lucas C., Dasgupta, Subhamoy, Dean, Adam, Stevenson, Connor R., Sivasubramanian, Natarajan, Sreekumar, Arun, DeMayo, Francesco, York, Brian, Fu, Loning, O’Malley, Bert W.

“…Synchrony of the mammalian circadian clock is achieved by complex transcriptional and translational feedback loops centered on the BMAL1:CLOCK heterodimer…”
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Research Resource: Loss of the Steroid Receptor Coactivators Confers Neurobehavioral Consequences by Stashi, Erin, Wang, Lei, Mani, Shailaja K, York, Brian, O'Malley, Bert W

“…Steroid receptor coactivators (SRCs) are important transcriptional modulators that regulate nuclear receptor and transcription factor activity to adjust…”
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SRC-2 orchestrates polygenic inputs for fine-tuning glucose homeostasis by Fleet, Tiffany, Zhang, Bin, Lin, Fumin, Zhu, Bokai, Dasgupta, Subhamoy, Stashi, Erin, Tackett, Bryan, Thevananther, Sundararajah, Rajapakshe, Kimal I., Gonzales, Naomi, Dean, Adam, Mao, Jianqiang, Timchenko, Nikolai, Malovannaya, Anna, Qin, Jun, Coarfa, Cristian, DeMayo, Francesco, Dacso, Clifford C., Foulds, Charles E., O’Malley, Bert W., York, Brian

“…Despite extensive efforts to understand the monogenic contributions to perturbed glucose homeostasis, the complexity of genetic events that fractionally…”
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SRC-2 coactivator deficiency decreases functional reserve in response to pressure overload of mouse heart by Reineke, Erin L, York, Brian, Stashi, Erin, Chen, Xian, Tsimelzon, Anna, Xu, Jianming, Newgard, Christopher B, Taffet, George E, Taegtmeyer, Heinrich, Entman, Mark L, O'Malley, Bert W

“…A major component of the cardiac stress response is the simultaneous activation of several gene regulatory networks. Interestingly, the transcriptional…”
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Steroid receptor coactivators: servants and masters for control of systems metabolism by Stashi, Erin, York, Brian, O’Malley, Bert W

“…Highlights • SRCs are required for diverse metabolic processes. • SRCs impact metabolic systems physiology. • SRC dysfunction confers metabolic…”
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Genetic and Environmental Models of Circadian Disruption Link SRC-2 Function to Hepatic Pathology by Fleet, Tiffany, Stashi, Erin, Zhu, Bokai, Rajapakshe, Kimal, Marcelo, Kathrina L., Kettner, Nicole M., Gorman, Blythe K., Coarfa, Cristian, Fu, Loning, O’Malley, Bert W., York, Brian

“…Circadian rhythmicity is a fundamental process that synchronizes behavioral cues with metabolic homeostasis. Disruption of daily cycles due to jet lag or shift…”
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Steroid Receptor Coactivator-2 Is a Dual Regulator of Cardiac Transcription Factor Function by Reineke, Erin L., Benham, Ashley, Soibam, Benjamin, Stashi, Erin, Taegtmeyer, Heinrich, Entman, Mark L., Schwartz, Robert J., O'Malley, Bert W.

“…We have previously demonstrated the potential role of steroid receptor coactivator-2 (SRC-2) as a co-regulator in the transcription of critical molecules…”
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Phase I trial of paclitaxel, bevacizumab, and temsirolimus in advanced solid malignancies by Westin, Shannon Neville, Stashi, Erin, Pal, Navdeep, Urbauer, Diana L, Janku, Filip, Piha-Paul, Sarina Anne, Naing, Aung, Tsimberidou, Apostolia Maria, Fu, Siqing, Hong, David S., Subbiah, Vivek, Karp, Daniel D., Coleman, Robert L., Meric-Bernstam, Funda, Kurzrock, Razelle

“…Abstract only…”
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Hepatic SRC-1 Activity Orchestrates Transcriptional Circuitries of Amino Acid Pathways with Potential Relevance for Human Metabolic Pathogenesis by Tannour-Louet, Mounia, York, Brian, Tang, Ke, Stashi, Erin, Bouguerra, Hichem, Zhou, Suoling, Yu, Hui, Wong, Lee-Jun C, Stevens, Robert D, Xu, Jianming, Newgard, Christopher B, O'Malley, Bert W, Louet, Jean-Francois

“…Disturbances in amino acid metabolism are increasingly recognized as being associated with, and serving as prognostic markers for chronic human diseases, such…”
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Anticipation of nitric oxide by a human-resident commensal microbe by Gustin, Michael, Lynn, Jed, Lorenz, Michael, Stashi, Erin, Sun, Lisa, Koveal, Dorothy

“…Candida albicans is a human-resident commensal fungus that occupies different locations in the gastrointestinal tract. C. albicans is regularly exposed to…”
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