Search Results - "Staroň, M."

CD4+ T Cell Help Guides Formation of CD103+ Lung-Resident Memory CD8+ T Cells during Influenza Viral Infection by Laidlaw, Brian J., Zhang, Nianzhi, Marshall, Heather D., Staron, Mathew M., Guan, Tianxia, Hu, Yinghong, Cauley, Linda S., Craft, Joe, Kaech, Susan M.

“…Tissue-resident memory T (Trm) cells provide enhanced protection against infection at mucosal sites. Here we found that CD4+ T cells are important for the…”
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The Transcription Factor FoxO1 Sustains Expression of the Inhibitory Receptor PD-1 and Survival of Antiviral CD8+ T Cells during Chronic Infection by Staron, Matthew M., Gray, Simon M., Marshall, Heather D., Parish, Ian A., Chen, Jonathan H., Perry, Curtis J., Cui, Guoliang, Li, Ming O., Kaech, Susan M.

“…Protein kinase B (also known as AKT) and the mechanistic target of rapamycin (mTOR) are central regulators of T cell differentiation, proliferation,…”
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Transcription Factor STAT3 and Type I Interferons Are Corepressive Insulators for Differentiation of Follicular Helper and T Helper 1 Cells by Ray, John P., Marshall, Heather D., Laidlaw, Brian J., Staron, Matthew M., Kaech, Susan M., Craft, Joe

“…Follicular helper T (Tfh) cells are required for the establishment of T-dependent B cell memory and high affinity antibody-secreting cells. We have revealed…”
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IL-7-Induced Glycerol Transport and TAG Synthesis Promotes Memory CD8+ T Cell Longevity by Cui, Guoliang, Staron, Matthew M., Gray, Simon M., Ho, Ping-Chih, Amezquita, Robert A., Wu, Jingxia, Kaech, Susan M.

“…Memory T cells are critical for long-term immunity against reinfection and require interleukin-7 (IL-7), but the mechanisms by which IL-7 controls memory…”
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The Interleukin-2-mTORc1 Kinase Axis Defines the Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells by Ray, John P., Staron, Matthew M., Shyer, Justin A., Ho, Ping-Chih, Marshall, Heather D., Gray, Simon M., Laidlaw, Brian J., Araki, Koichi, Ahmed, Rafi, Kaech, Susan M., Craft, Joe

“…The differentiation of CD4+ helper T cell subsets with diverse effector functions is accompanied by changes in metabolism required to meet their bioenergetic…”
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Prostaglandin E2 and programmed cell death 1 signaling coordinately impair CTL function and survival during chronic viral infection by Chen, Jonathan H, Perry, Curtis J, Tsui, Yao-Chen, Staron, Matthew M, Parish, Ian A, Dominguez, Claudia X, Rosenberg, Daniel W, Kaech, Susan M

“…Susan Kaech and colleagues report that in chronic viral infection, prostaglandin E2 and PD-1 signaling suppressed the function and survival of cytotoxic T…”
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A functional subset of CD8+ T cells during chronic exhaustion is defined by SIRPα expression by Myers, Lara M., Tal, Michal Caspi, Torrez Dulgeroff, Laughing Bear, Carmody, Aaron B., Messer, Ronald J., Gulati, Gunsagar, Yiu, Ying Ying, Staron, Matthew M., Angel, Cesar Lopez, Sinha, Rahul, Markovic, Maxim, Pham, Edward A., Fram, Benjamin, Ahmed, Aijaz, Newman, Aaron M., Glenn, Jeffrey S., Davis, Mark M., Kaech, Susan M., Weissman, Irving L., Hasenkrug, Kim J.

“…Prolonged exposure of CD8 + T cells to antigenic stimulation, as in chronic viral infections, leads to a state of diminished function termed exhaustion. We now…”
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Multi-Omics Characterization of Colon Mucosa and Submucosa/Wall from Crohn's Disease Patients by Jin, Liang, Macoritto, Michael, Wang, Jing, Bi, Yingtao, Wang, Fei, Suarez-Fueyo, Abel, Paez-Cortez, Jesus, Hu, Chenqi, Knight, Heather, Mascanfroni, Ivan, Staron, Matthew M, Schwartz Sterman, Annette, Houghton, Jean Marie, Westmoreland, Susan, Tian, Yu

“…Crohn's disease (CD) is a subtype of inflammatory bowel disease (IBD) characterized by transmural disease. The concept of transmural healing (TH) has been…”
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The First Record of Facultative Parasitism of Megaselia Spp. (Diptera: Phoridae) in a Honeybee Colony in Slovakia by Sabo R., Legáth J., Staroň M., Sabová L.

“…The current global climate warming trend leads to a shift in animal-habitats northwards. According to the Slovak Hydrometeorological Institute, summer 2018 was…”
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The transforming growth factor beta signaling pathway is critical for the formation of CD4 T follicular helper cells and isotype-switched antibody responses in the lung mucosa by Marshall, Heather D, Ray, John P, Laidlaw, Brian J, Zhang, Nianzhi, Gawande, Dipika, Staron, Matthew M, Craft, Joe, Kaech, Susan M

“…T follicular helper cells (Tfh) are crucial for the initiation and maintenance of germinal center (GC) reactions and high affinity, isotype-switched antibody…”
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Potent and conditional redirected T cell killing of tumor cells using Half DVD-Ig by Bardwell, Philip D., Staron, Matthew M., Liu, Junjian, Tao, Qingfeng, Scesney, Susanne, Bukofzer, Gail, Rodriguez, Luis E., Choi, Chee-Ho, Wang, Jennifer, Chang, Qing, Dong, Feng, Donawho, Cherrie, Wang, Jieyi, Grinnell, Christine M., Tarcsa, Edit, Hutchins, Charles, Ghayur, Tariq, Gu, Jijie

“…Novel biologics that redirect cytotoxic T lymphocytes (CTLs) to kill tumor cells bearing a tumor associated antigen hold great promise in the clinic. However,…”
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Questionable suitability of OECD 237 protocol in risk assessment scheme? by Sabo, R., Staroň, M., Sobeková, A., Sabová, L., Legáth, J., Javorský, P.

“…Persistent xenobiotics are potentially hazardous for the bee larvae despite that they are not directly exposed in contrary to adult foraging bees. The crucial…”
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The interface between transcriptional and epigenetic control of effector and memory CD8+ T-cell differentiation by Gray, Simon M., Kaech, Susan M., Staron, Matthew M.

“…Summary Immunity to many intracellular pathogens requires the proliferation, differentiation, and function of CD8+ cytotoxic T lymphocytes (CTLs). While the…”
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Chronic viral infection promotes sustained Th1-derived immunoregulatory IL-10 via BLIMP-1 by Parish, Ian A, Marshall, Heather D, Staron, Matthew M, Lang, Philipp A, Brüstle, Anne, Chen, Jonathan H, Cui, Weiguo, Tsui, Yao-Chen, Perry, Curtis, Laidlaw, Brian J, Ohashi, Pamela S, Weaver, Casey T, Kaech, Susan M

“…During the course of many chronic viral infections, the antiviral T cell response becomes attenuated through a process that is regulated in part by the host…”
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Characterization of Diabetogenic CD8+ T Cells: IMMUNE THERAPY WITH METABOLIC BLOCKADE by Garyu, Justin W, Uduman, Mohamed, Stewart, Alex, Rui, Jinxiu, Deng, Songyan, Shenson, Jared, Staron, Matt M, Kaech, Susan M, Kleinstein, Steven H, Herold, Kevan C

“…Type 1 diabetes mellitus is caused by the killing of insulin-producing β cells by CD8+T cells. The disease progression, which is chronic, does not follow a…”
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Correction: The transforming growth factor beta signaling pathway is critical for the formation of CD4 T follicular helper cells and isotype-switched antibody responses in the lung mucosa by Marshall, Heather D, Ray, John P, Laidlaw, Brian J, Zhang, Nianzhi, Gawande, Dipika, Staron, Matthew M, Craft, Joe, Kaech, Susan M

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REE signatures in vertebrate fossils from Sewell, NJ; implications for location of the K-T boundary by Staron, Richard M, Grandstaff, Barbara S, Gallagher, William B, Grandstaff, David E

“…Rare Earth Element (REE) signatures have been used to test whether mosasaur bones in a basal Hornerstown Formation bonebed (the Main Fossiliferous Layer, or…”
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Industrial experiences from evolving measurement systems into self‐healing systems for improved availability by Staron, Miroslaw, Meding, Wilhelm, Tichy, Matthias, Bjurhede, Jonas, Giese, Holger, Söder, Ola

“…Summary Automated measurement programs are an efficient way of collecting, processing, and visualizing measures in large software development companies. The…”
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Using Students as Subjects in Experiments--A Quantitative Analysis of the Influence of Experimentation on Students' Learning Proces by Staron, M.

“…The purpose of this study is to evaluate whether using students as subjects in software engineering experiments improves their learning process. In this paper…”
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An empirical study on using stereotypes to improve understanding of UML models by Kuzniarz, L., Staron, M., Wohlin, C.

“…Stereotypes were introduced into the Unified Modeling Language (UML) to provide means of customizing this visual, general purpose, object-oriented modeling…”
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