Search Results - "Stark, L L"

Impaired hippocampal-prefrontal synchrony in a genetic mouse model of schizophrenia by Gogos, Joseph A, Gordon, Joshua A, Sigurdsson, Torfi, Stark, Kimberly L, Karayiorgou, Maria

“…Abnormalities in functional connectivity between brain areas have been postulated as an important pathophysiological mechanism underlying schizophrenia. In…”
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Chronic calorie restriction attenuates experimental autoimmune encephalomyelitis by Piccio, Laura, Stark, Jennifer L., Cross, Anne H.

“…Calorie restriction (CR) prevents many age‐associated diseases and prolongs the lifespan. CR induces multiple metabolic and physiologic modifications,…”
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Derepression of a Neuronal Inhibitor due to miRNA Dysregulation in a Schizophrenia-Related Microdeletion by Xu, Bin, Hsu, Pei-Ken, Stark, Kimberly L., Karayiorgou, Maria, Gogos, Joseph A.

“…22q11.2 microdeletions result in specific cognitive deficits and schizophrenia. Analysis of Df(16)A+/− mice, which model this microdeletion, revealed…”
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Pattern Separation in the Human Hippocampal CA3 and Dentate Gyrus by Bakker, Arnold, Kirwan, C. Brock, Miller, Michael, Stark, Craig E.L

“…Pattern separation, the process of transforming similar representations or memories into highly dissimilar, nonoverlapping representations, is a key component…”
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Trem2 Deletion Reduces Late-Stage Amyloid Plaque Accumulation, Elevates the Aβ42:Aβ40 Ratio, and Exacerbates Axonal Dystrophy and Dendritic Spine Loss in the PS2APP Alzheimer's Mouse Model by Meilandt, William J, Ngu, Hai, Gogineni, Alvin, Lalehzadeh, Guita, Lee, Seung-Hye, Srinivasan, Karpagam, Imperio, Jose, Wu, Tiffany, Weber, Martin, Kruse, Agatha J, Stark, Kimberly L, Chan, Pamela, Kwong, Mandy, Modrusan, Zora, Friedman, Brad A, Elstrott, Justin, Foreman, Oded, Easton, Amy, Sheng, Morgan, Hansen, David V

“…is an Alzheimer's disease (AD) risk gene expressed in microglia. To study the role of in a mouse model of β-amyloidosis, we compared PS2APP transgenic mice…”
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Age-related memory deficits linked to circuit-specific disruptions in the hippocampus by Yassa, Michael A, Mattfeld, Aaron T, Stark, Shauna M, Stark, Craig E.L

“…Converging data from rodents and humans have demonstrated an age-related decline in pattern separation abilities (the ability to discriminate among similar…”
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Masculinity Contest Cultures in Policing Organizations and Recommendations for Training Interventions by Rawski, Shannon L., Workman‐Stark, Angela L.

“…In the wake of the #BlackLivesMatter and #MeToo movements, police conduct has been increasingly scrutinized by the public, especially the use of excessive…”
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Age‐related alterations in functional connectivity along the longitudinal axis of the hippocampus and its subfields by Stark, Shauna M., Frithsen, Amy, Stark, Craig E.L.

“…Hippocampal circuit alterations that differentially affect hippocampal subfields are associated with age‐related memory decline. Additionally, functional…”
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A task to assess behavioral pattern separation (BPS) in humans: Data from healthy aging and mild cognitive impairment by Stark, Shauna M., Yassa, Michael A., Lacy, Joyce W., Stark, Craig E.L.

“…Changes in memory performance are one of the hallmark symptoms of mild cognitive impairment and are affected by healthy aging as well. Pattern separation,…”
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The neuroscience of memory: implications for the courtroom by Lacy, Joyce W., Stark, Craig E. L.

“…Psychology and neuroscience studies have shown that memory is a reconstructive process that is susceptible to distortion. Lacy and Stark summarize the evidence…”
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Behavioral characterization of a CRISPR-generated TRPA1 knockout rat in models of pain, itch, and asthma by Reese, Rebecca M., Dourado, Michelle, Anderson, Keith, Warming, Søren, Stark, Kimberly L., Balestrini, Alessia, Suto, Eric, Lee, Wyne, Riol-Blanco, Lorena, Shields, Shannon D., Hackos, David H.

“…The transient receptor potential (TRP) superfamily of ion channels has garnered significant attention by the pharmaceutical industry. In particular, TRP…”
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False memories in highly superior autobiographical memory individuals by Patihis, Lawrence, Frenda, Steven J., LePort, Aurora K. R., Petersen, Nicole, Nichols, Rebecca M., Stark, Craig E. L., McGaugh, James L., Loftus, Elizabeth F.

“…The recent identification of highly superior autobiographical memory (HSAM) raised the possibility that there may be individuals who are immune to memory…”
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Ultrahigh-resolution microstructural diffusion tensor imaging reveals perforant path degradation in aged humans in vivo by Yassa, Michael A., Muftuler, L. Tugan, Stark, Craig E. L., Squire, Larry R.

“…The perforant path (PP) undergoes synaptic changes in the course of aging and dementia. Previous studies attempting to assess the integrity of the PP in humans…”
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Microstructural Alterations in Hippocampal Subfields Mediate Age-Related Memory Decline in Humans by Radhakrishnan, Hamsanandini, Stark, Shauna M, Stark, Craig E L

“…Aging, even in the absence of clear pathology of dementia, is associated with cognitive decline. Neuroimaging, especially diffusion-weighted imaging, has been…”
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Haploinsufficient lethality and formation of arteriovenous malformations in Notch pathway mutants by Krebs, Luke T, Shutter, John R, Tanigaki, Kenji, Honjo, Tasuku, Stark, Kevin L, Gridley, Thomas

“…The Notch signaling pathway is essential for embryonic vascular development in vertebrates. Here we show that mouse embryos heterozygous for a targeted…”
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Pattern of failure after adjuvant radiotherapy following extrapleural pneumonectomy of pleural mesothelioma in the SAKK 17/04 trial by Riesterer, Oliver, Frank Ciernik, I, Stahel, Rolf A, Xyrafas, Alexandros, Aebersold, Daniel M, Plasswilm, Ludwig, Mahmut Ozsahin, E, Zwahlen, Daniel R, Nackaerts, Kristiaan, Zimmermann, Frank, Sabrina Stark, L, Weder, Walter, Krayenbuehl, Jérôme

“…AbstractPostoperative radiotherapy after extrapleural pneumonectomy of malignant pleural mesothelioma was investigated in the randomized phase II trial…”
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Nucleolar NF-κB/RelA mediates apoptosis by causing cytoplasmic relocalization of nucleophosmin by Khandelwal, N, Simpson, J, Taylor, G, Rafique, S, Whitehouse, A, Hiscox, J, Stark, L A

“…In a number of contexts, and particularly in response to cellular stress, stimulation of the NF-kappaB (NF- κ B) pathway promotes apoptosis. One mechanism…”
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Retrieval of high-fidelity memory arises from distributed cortical networks by Wais, Peter E., Jahanikia, Sahar, Steiner, Daniel, Stark, Craig E.L., Gazzaley, Adam

“…Medial temporal lobe (MTL) function is well established as necessary for memory of facts and events. It is likely that lateral cortical regions critically…”
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Anti-α-synuclein c-terminal antibodies block PFF uptake and accumulation of phospho-synuclein in preclinical models of Parkinson's disease by Brendza, Robert, Gao, Xiaoying, Stark, Kimberly L., Lin, Han, Lee, Seung-Hye, Hu, Changyun, Cai, Hao, DiCara, Danielle, Hsiao, Yi-Chun, Ngu, Hai, Foreman, Oded, Baca, Miriam, Dohse, Monika, Fortin, Jean-Phillipe, Corpuz, Racquel, Seshasayee, Dhaya, Easton, Amy, Ayalon, Gai, Hötzel, Isidro, Chih, Ben

“…Parkinson's disease (PD), a neurodegenerative disease affecting dopaminergic (DA) neurons, is characterized by decline of motor function and cognition…”
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Barriers to treatment optimization and achievement of patients' goals: perspectives from people living with rheumatoid arthritis enrolled in the ArthritisPower registry by Gavigan, Kelly, Nowell, W Benjamin, Serna, Mylene S, Stark, Jeffrey L, Yassine, Mohamed, Curtis, Jeffrey R

“…Few studies have investigated patients' own treatment goals in rheumatoid arthritis (RA). The objective of this real-world, cross-sectional study of US…”
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