Search Results - "Stark, Craig E. L."
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Pattern Separation in the Human Hippocampal CA3 and Dentate Gyrus
Published in Science (American Association for the Advancement of Science) (21-03-2008)“…Pattern separation, the process of transforming similar representations or memories into highly dissimilar, nonoverlapping representations, is a key component…”
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A task to assess behavioral pattern separation (BPS) in humans: Data from healthy aging and mild cognitive impairment
Published in Neuropsychologia (01-10-2013)“…Changes in memory performance are one of the hallmark symptoms of mild cognitive impairment and are affected by healthy aging as well. Pattern separation,…”
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Journal Article Conference Proceeding -
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Age-related memory deficits linked to circuit-specific disruptions in the hippocampus
Published in Proceedings of the National Academy of Sciences - PNAS (24-05-2011)“…Converging data from rodents and humans have demonstrated an age-related decline in pattern separation abilities (the ability to discriminate among similar…”
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False memories in highly superior autobiographical memory individuals
Published in Proceedings of the National Academy of Sciences - PNAS (24-12-2013)“…The recent identification of highly superior autobiographical memory (HSAM) raised the possibility that there may be individuals who are immune to memory…”
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Ultrahigh-resolution microstructural diffusion tensor imaging reveals perforant path degradation in aged humans in vivo
Published in Proceedings of the National Academy of Sciences - PNAS (13-07-2010)“…The perforant path (PP) undergoes synaptic changes in the course of aging and dementia. Previous studies attempting to assess the integrity of the PP in humans…”
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Functional MRI of the amygdala and bed nucleus of the stria terminalis during conditions of uncertainty in generalized anxiety disorder
Published in Journal of psychiatric research (01-08-2012)“…Abstract Generalized anxiety disorder (GAD) is a common psychiatric disorder characterized by constant worry or anxiety over every day life activities and…”
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Behavioral and neuroanatomical investigation of Highly Superior Autobiographical Memory (HSAM)
Published in Neurobiology of learning and memory (01-07-2012)“…► Eleven Highly Superior Autobiographical Memory (HSAM) participants were identified. ► HSAM participants were significantly better at recalling…”
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Pattern separation deficits following damage to the hippocampus
Published in Neuropsychologia (01-08-2012)“…Computational models of hippocampal function propose that the hippocampus is capable of rapidly storing distinct representations through a process known as…”
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Imaging the Reconstruction of True and False Memories Using Sensory Reactivation and the Misinformation Paradigms
Published in Learning & memory (Cold Spring Harbor, N.Y.) (01-10-2010)“…Many current theories of false memories propose that, when we retrieve a memory, we are not reactivating a veridical, fixed representation of a past event, but…”
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Retrieval of high-fidelity memory arises from distributed cortical networks
Published in NeuroImage (Orlando, Fla.) (01-04-2017)“…Medial temporal lobe (MTL) function is well established as necessary for memory of facts and events. It is likely that lateral cortical regions critically…”
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Functional Specialization within the Striatum along Both the Dorsal/Ventral and Anterior/Posterior Axes during Associative Learning via Reward and Punishment
Published in Learning & memory (Cold Spring Harbor, N.Y.) (01-11-2011)“…The goal of the present study was to elucidate the role of the human striatum in learning via reward and punishment during an associative learning task…”
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Pattern separation in the hippocampus
Published in Trends in neurosciences (Regular ed.) (01-10-2011)“…The ability to discriminate among similar experiences is a crucial feature of episodic memory. This ability has long been hypothesized to require the…”
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Stability of Age-Related Deficits in the Mnemonic Similarity Task Across Task Variations
Published in Behavioral neuroscience (01-06-2015)“…Several studies in our lab and others have demonstrated age-related declines in mnemonic discrimination during a recognition memory paradigm using repeated…”
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Journal Article -
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Virtual Environmental Enrichment through Video Games Improves Hippocampal-Associated Memory
Published in The Journal of neuroscience (09-12-2015)“…The positive effects of environmental enrichment and their neural bases have been studied extensively in the rodent (van Praag et al., 2000). For example,…”
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The neuroscience of memory: implications for the courtroom
Published in Nature reviews. Neuroscience (01-09-2013)“…Psychology and neuroscience studies have shown that memory is a reconstructive process that is susceptible to distortion. Lacy and Stark summarize the evidence…”
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Journal Article Book Review -
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Memory for Sequences of Events Impaired in Typical Aging
Published in Learning & memory (Cold Spring Harbor, N.Y.) (01-03-2015)“…Typical aging is associated with diminished episodic memory performance. To improve our understanding of the fundamental mechanisms underlying this age-related…”
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Item Memory, Source Memory, and the Medial Temporal Lobe: Concordant Findings from fMRI and Memory-Impaired Patients
Published in Proceedings of the National Academy of Sciences - PNAS (13-06-2006)“…We studied item and source memory with fMRI in healthy volunteers and carried out a parallel study in memory-impaired patients. In experiment 1, volunteers…”
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High-resolution structural and functional MRI of hippocampal CA3 and dentate gyrus in patients with amnestic Mild Cognitive Impairment
Published in NeuroImage (Orlando, Fla.) (01-07-2010)“…Functional magnetic resonance imaging (fMRI) studies have observed hyperactivity in the hippocampal region in individuals with Mild Cognitive Impairment (MCI)…”
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Microstructural Alterations in Hippocampal Subfields Mediate Age-Related Memory Decline in Humans
Published in Frontiers in aging neuroscience (09-04-2020)“…Aging, even in the absence of clear pathology of dementia, is associated with cognitive decline. Neuroimaging, especially diffusion-weighted imaging, has been…”
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Individual Differences in Spatial Pattern Separation Performance Associated with Healthy Aging in Humans
Published in Learning & memory (Cold Spring Harbor, N.Y.) (01-06-2010)“…Rodent studies have suggested that "pattern separation," the ability to distinguish among similar experiences, is diminished in a subset of aged rats. We…”
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