Search Results - "Starc, Nadia"
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Biological and functional characterization of bone marrow-derived mesenchymal stromal cells from patients affected by primary immunodeficiency
Published in Scientific reports (15-08-2017)“…Mesenchymal stromal cells (MSCs) represent a key component of bone marrow (BM) microenvironment and display immune-regulatory properties. We performed a…”
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Identification of a Genetic Variation in ERAP1 Aminopeptidase that Prevents Human Cytomegalovirus miR-UL112-5p-Mediated Immunoevasion
Published in Cell reports (Cambridge) (25-07-2017)“…Herein, we demonstrate that HCMV miR-UL112-5p targets ERAP1, thereby inhibiting the processing and presentation of the HCMV pp65495-503 peptide to specific…”
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Biological, functional and genetic characterization of bone marrow-derived mesenchymal stromal cells from pediatric patients affected by acute lymphoblastic leukemia
Published in PloS one (07-11-2013)“…Alterations in hematopoietic microenvironment of acute lymphoblastic leukemia patients have been claimed to occur, but little is known about the components of…”
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Microvescicles derived from mesenchymal stromal cells are not as effective as their cellular counterpart in the ability to modulate immune responses in vitro
Published in Stem cells and development (01-11-2014)“…Mesenchymal stromal cells (MSCs) are multipotent cells that possess broad immunomodulatory properties; the mechanisms underlying these properties have not been…”
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Assessing the relationship between cardiovascular and small airway disease and acute events in COPD: The ARCADIA study protocol
Published in Pulmonary pharmacology & therapeutics (01-10-2023)“…The initial alterations of chronic obstructive pulmonary disease (COPD) involve the small airways. Small airway disease (SAD) is related to lung hyperinflation…”
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CB2 and TRPV1 receptors oppositely modulate in vitro human osteoblast activity
Published in Pharmacological research (01-09-2015)“…In the current study, we have investigated the effect of CB2 and TRPV1 receptor ligands on in vitro osteoblasts from bone marrow of human healthy donors. A…”
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Comprehensive characterization of mesenchymal stromal cells from patients with Fanconi anaemia
Published in British journal of haematology (01-09-2015)“…Summary Fanconi anaemia (FA) is an inherited disorder characterized by pancytopenia, congenital malformations and a predisposition to develop malignancies…”
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Phenotypic and functional characterization of mesenchymal stromal cells isolated from pediatric patients with severe idiopathic nephrotic syndrome
Published in Cytotherapy (Oxford, England) (01-03-2018)“…Abstract Background Idiopathic nephrotic syndrome (INS) is one of the most common renal diseases in the pediatric population; considering the role of the…”
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Cysteamine treatment restores the in vitro ability to differentiate along the osteoblastic lineage of mesenchymal stromal cells isolated from bone marrow of a cystinotic patient
Published in Journal of translational medicine (07-05-2015)“…Cystinosis is a rare autosomal recessive disease caused by mutations of the CTNS gene, which encodes for a lysosomal cystine/H(+) symporter. In mice,…”
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Resistance to neoplastic transformation of ex-vivo expanded human mesenchymal stromal cells after exposure to supramaximal physical and chemical stress
Published in Oncotarget (22-11-2016)“…The risk of malignant transformation of ex-vivo expanded human mesenchymal stromal cells (huMSCs) has been debated in the last years; however, the biosafety of…”
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A registry of HLA ‐typed donors for production of virus‐specific CD 4 and CD 8 T lymphocytes for adoptive reconstitution of immune‐compromised patients
Published in Transfusion (Philadelphia, Pa.) (01-12-2014)“…Background Virus‐specific CD 4 and CD 8 T lymphocytes from HLA ‐matched donors are effective for treatment and prophylaxis of viral infections in…”
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Miniaturized and high-throughput assays for analysis of T-cell immunity specific for opportunistic pathogens and HIV
Published in Clinical and vaccine immunology (01-04-2014)“…Monitoring of antigen-specific T-cell responses is valuable in numerous conditions that include infectious diseases, vaccinations, and opportunistic infections…”
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A registry of HLA-typed donors for production of virus-specific CD4 and CD8 T lymphocytes for adoptive reconstitution of immune-compromised patients
Published in Transfusion (Philadelphia, Pa.) (01-12-2014)“…Background Virus‐specific CD4 and CD8 T lymphocytes from HLA‐matched donors are effective for treatment and prophylaxis of viral infections in…”
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Lymphocyte proliferation specific for recall, CMV and HIV antigens in miniaturized and automated format
Published in Journal of immunological methods (31-10-2012)“…Lymphoproliferation assay (LPA) is used to test specific T-cell responses. LPA is performed in 96-well plates with 2–5×105 PBMC/well. In order to test numerous…”
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Characterization of the immunomodulatory effect in vitro of microvesicles isolated from mesenchymal stromal cells on immune cells
Published in Experimental hematology (01-08-2013)Get full text
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CB(2) and TRPV(1) receptors oppositely modulate in vitro human osteoblast activity
Published in Pharmacological research (01-09-2015)“…In the current study, we have investigated the effect of CB2 and TRPV1 receptor ligands on in vitro osteoblasts from bone marrow of human healthy donors. A…”
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Biological, Functional and Genetic Characterization of Bone Marrow-Derived Mesenchymal Stromal Cells from Pediatric Patients Affected by Acute Lymphoblastic Leukemia: e76989
Published in PloS one (01-11-2013)“…Alterations in hematopoietic microenvironment of acute lymphoblastic leukemia patients have been claimed to occur, but little is known about the components of…”
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