Search Results - "Stapleton, P P"

Toxicological considerations of nano-sized plastics by Stapleton, PA

“…Undoubtedly, plastics have changed human existence. These pervasive products are used in nearly every field to include technological, biomedical, and domestic…”
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Gestational nanomaterial exposures: microvascular implications during pregnancy, fetal development and adulthood by Stapleton, P. A.

“…Air pollution particulate matter and engineered nanomaterials are encompassed in the broad definition of xenobiotic particles. While the effects of perinatal…”
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Tocilizumab (Actemra) by Sheppard, Martin, Laskou, Faidra, Stapleton, Philip P., Hadavi, Shahryar, Dasgupta, Bhaskar

“…Tocilizumab (TCZ), is a recombinant humanized anti-interleukin-6 receptor (IL-6R) monoclonal antibody which has a main use in the treatment of rheumatoid…”
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Nanoparticles at the maternal-fetal interface by Adams, S., Stapleton, P.A.

“…The increasing production of intentional and unintentional nanoparticles (NPs) has led to their accumulation in the environment as air and ground pollution…”
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Australian Community and Health Professionals Perceptions of Equine-Assisted Psychotherapy by Stapleton, P., Grimmett, K. T.

“…Mental health conditions are increasingly prevalent in the Australian population, and despite the large evidence-based support for contemporary treatments,…”
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Maternal, placental, and fetal distribution of titanium after repeated titanium dioxide nanoparticle inhalation through pregnancy by D'Errico, J.N., Doherty, C., Reyes George, J.J., Buckley, B., Stapleton, P.A.

“…Epidemiological studies have associated ambient engineered nanomaterials or ultrafine particulate matter (PM0.1), collectively referred to as nanoparticles…”
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Single pulmonary nanopolystyrene exposure in late-stage pregnancy dysregulates maternal and fetal cardiovascular function by Cary, C M, Fournier, S B, Adams, S, Wang, X, Yurkow, E J, Stapleton, P A

“…Abstract Large-scale production and waste of plastic materials have resulted in widespread environmental contamination by the breakdown product of bulk plastic…”
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NPHP1 (Nephrocystin-1) Gene Deletions Cause Adult-Onset ESRD by Snoek, Rozemarijn, van Setten, Jessica, Keating, Brendan J, Israni, Ajay K, Jacobson, Pamala A, Oetting, William S, Matas, Arthur J, Mannon, Roslyn B, Zhang, Zhongyang, Zhang, Weijia, Hao, Ke, Murphy, Barbara, Reindl-Schwaighofer, Roman, Heinzl, Andreas, Oberbauer, Rainer, Viklicky, Ondrej, Conlon, Peter J, Stapleton, Caragh P, Bakker, Stephan J L, Snieder, Harold, Peters, Edith D J, van der Zwaag, Bert, Knoers, Nine V A M, de Borst, Martin H, van Eerde, Albertien M

“…Nephronophthisis (NPH) is the most prevalent genetic cause for ESRD in children. However, little is known about the prevalence of NPH in adult-onset ESRD…”
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Maternal engineered nanomaterial inhalation during gestation alters the fetal transcriptome by Stapleton, P A, Hathaway, Q A, Nichols, C E, Abukabda, A B, Pinti, M V, Shepherd, D L, McBride, C R, Yi, J, Castranova, V C, Hollander, J M, Nurkiewicz, T R

“…The integration of engineered nanomaterials (ENM) is well-established and widespread in clinical, commercial, and domestic applications. Cardiovascular…”
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Effect of Gestational Age on Maternofetal Vascular Function Following Single Maternal Engineered Nanoparticle Exposure by Fournier, S. B., Kallontzi, S., Fabris, L., Love, C., Stapleton, P. A.

“…Normal pregnancy outcome is accomplished, in part, by rapid and expansive physiological adaptations to the systemic circulation, the extent of which is…”
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Staphylococcus aureus interaction with Pseudomonas aeruginosa biofilm enhances tobramycin resistance by Beaudoin, T., Yau, Y. C. W., Stapleton, P. J., Gong, Y., Wang, P. W., Guttman, D. S., Waters, V.

“…Antimicrobial resistance is a significant threat to the treatment of infectious disease. Multiple mechanisms of resistance to different classes of antibiotics…”
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Engineered nanomaterial applications in perinatal therapeutics by Fournier, S.B., D’Errico, J.N., Stapleton, P.A.

“…[Display omitted] Engineered nanomaterials (ENM) are widely used in commercial, domestic, and more recently biomedical applications. While the majority of…”
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Evaluating the use of whole genome sequencing for the investigation of a large mumps outbreak in Ontario, Canada by Stapleton, P. J., Eshaghi, A., Seo, C. Y., Wilson, S., Harris, T., Deeks, S. L., Bolotin, S., Goneau, L. W., Gubbay, J. B., Patel, S. N.

“…In 2017 Ontario experienced the largest mumps outbreak in the province in 8 years, at a time when multiple outbreaks were occurring across North America. Of…”
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Repeated transmission of SARS-CoV-2 in an overcrowded Irish emergency department elucidated by whole-genome sequencing by Hare, D., Meaney, C., Powell, J., Slevin, B., O' Brien, B., Power, L., O' Connell, N.H., De Gascun, C.F., Dunne, C.P., Stapleton, P.J.

“…To provide a detailed genomic-epidemiological description of a complex multi-ward SARS-CoV-2 outbreak, which originated in the crowded emergency department…”
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Whole-genome sequencing to investigate transmission of SARS-CoV-2 in the acute healthcare setting: a systematic review by Hare, D., Dembicka, K.M., Brennan, C., Campbell, C., Sutton-Fitzpatrick, U., Stapleton, P.J., De Gascun, C.F., Dunne, C.P.

“…Whole-genome sequencing (WGS) has been used widely to elucidate transmission of SARS-CoV-2 in acute healthcare settings, and to guide infection, prevention,…”
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Estrous cycle-dependent modulation of in vivo microvascular dysfunction after nanomaterial inhalation by Stapleton, P.A., McBride, C.R., Yi, J., Abukabda, A.B., Nurkiewicz, T.R.

“…•This is the first study to evaluate toxicological exposures using intravital microscopy to evaluate arteriolar function throughout the estrous cycle and in…”
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Identification and quantification of gold engineered nanomaterials and impaired fluid transfer across the rat placenta via ex vivo perfusion by D’Errico, J.N., Doherty, C., Fournier, S.B., Renkel, N., Kallontzi, S., Goedken, M., Fabris, L., Buckley, B., Stapleton, P.A.

“…•Morphological barriers remain intact using our ex vivo placental perfusion technique.•Gold nanoparticles can translocate across the placenta within 20 min of…”
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Advantages of melodic over rhythmic movement sonification in bimanual motor skill learning by Dyer, J. F., Stapleton, P., Rodger, M. W. M.

“…An important question for skill acquisition is whether and how augmented feedback can be designed to improve the learning of complex skills. Auditory…”
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Uterine microvascular sensitivity to nanomaterial inhalation: An in vivo assessment by Stapleton, P.A., McBride, C.R., Yi, J., Nurkiewicz, T.R.

“…With the tremendous number and diverse applications of engineered nanomaterials incorporated in daily human activity, exposure can no longer be solely confined…”
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Association analysis of single nucleotide polymorphisms in DGAT1, TG and FABP4 genes and intramuscular fat in crossbred Bos taurus cattle by Pannier, L., Mullen, A.M., Hamill, R.M., Stapleton, P.C., Sweeney, T.

“…Previous studies have indicated that single nucleotide polymorphisms (SNPs) in the diacylglycerol-O-acyltransferase1 ( DGAT1), thyroglobulin ( TG) and adipose…”
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