Search Results - "Staples, Maree K"
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Oxidized Cholesterol Metabolites Found in Human Atherosclerotic Lesions Promote Apolipoprotein C-II Amyloid Fibril Formation
Published in Biochemistry (Easton) (08-05-2007)“…Apolipoprotein amyloid deposits and lipid oxidation products are colocalized in human atherosclerotic tissue. In this study we show that the primary ozonolysis…”
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Tandem free-radical addition/substitution chemistry and its application to the preparation of novel AT1 receptor antagonists
Published in Organic & biomolecular chemistry (21-01-2011)“…Benzothiophene and benzoselenophene analogues of the thiophene-containing antihypertensives milfasartan and eprosartan were prepared and tested for AT(1)…”
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Selenochromanes via tandem homolytic addition/substitution chemistry
Published in Chemical communications (Cambridge, England) (01-01-2010)“…Selenochromanes and analogues are conveniently prepared through a tandem homolytic addition/substitution sequence involving suitably substituted olefins…”
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Oxidation of Low-Density Lipoproteins Induces Amyloid-like Structures That Are Recognized by Macrophages
Published in Biochemistry (Easton) (28-06-2005)“…The macrophage scavenger receptor CD36 plays a key role in the initiation of atherosclerosis through its ability to bind to and internalize oxidized…”
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