Search Results - "Stap, J."

A Novel Role for the Thyroid Hormone-Activating Enzyme Type 2 Deiodinase in the Inflammatory Response of Macrophages by Kwakkel, J, Surovtseva, O.V, de Vries, E.M, Stap, J, Fliers, E, Boelen, A

“…Deiodinase type 2 (D2) is a thyroid hormone-activating enzyme converting the prohormone T4 into the active hormone T3. In the present study, we show for the…”
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Chromatin mobility is increased at sites of DNA double-strand breaks by Krawczyk, P M, Borovski, T, Stap, J, Cijsouw, T, ten Cate, R, Medema, J P, Kanaar, R, Franken, N A P, Aten, J A

“…DNA double-strand breaks (DSBs) can efficiently kill cancer cells, but they can also produce unwanted chromosome rearrangements when DNA ends from different…”
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Histatin 1 Enhances Cell Adhesion to Titanium in an Implant Integration Model by van Dijk, I.A., Beker, A.F., Jellema, W., Nazmi, K., Wu, G., Wismeijer, D., Krawczyk, P.M., Bolscher, J.G.M., Veerman, E.C.I., Stap, J.

“…Cellular adhesion is essential for successful integration of dental implants. Rapid soft tissue integration is important to create a seal around the implant…”
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Foraging behaviour and ecology of transient killer whales within a deep submarine canyon system by McInnes, Josh D, Lester, Kevin M, Dill, Lawrence M, Mathieson, Chelsea R, West-Stap, Peggy J, Marcos, Stephanie L, Trites, Andrew W

“…Transient killer whales have been documented hunting marine mammals across a variety of habitats. However, relatively little has been reported about their…”
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Cholinergic receptor activation on epithelia protects against cytokine-induced barrier dysfunction by Dhawan, S., Hiemstra, I. H., Verseijden, C., Hilbers, F. W., te Velde, A. A., Willemsen, L. E. M., Stap, J., den Haan, J. M., de Jonge, W. J.

“…Aim Various types of cholinergic receptors are expressed on intestinal epithelia. Their function is not completely understood. We hypothesize that cholinergic…”
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Protease‐activated receptor‐2 induces migration of pancreatic cancer cells in an extracellular ATP‐dependent manner by Shi, K., Queiroz, K. C. S., Stap, J., Richel, D. J., Spek, C. A.

“…Summary Background Protease‐activated receptor 2 (PAR‐2) is a G protein‐coupled receptor suggested to play an important role in the proliferation and migration…”
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Active caspase-3 is removed from cells by release of caspase-3-enriched vesicles by Böing, A.N., Stap, J., Hau, C.M., Afink, G.B., Ris-Stalpers, C., Reits, E.A., Sturk, A., van Noorden, C.J.F., Nieuwland, R.

“…Cleavage of Rho associated Coiled Coil kinase I (ROCK I) by caspase-3 contributes to membrane blebbing. Whether caspase-3 and ROCK I also play a role in the…”
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O4.08 AGI5198, AN INHIBITOR OF IDH1R132H, PROTECTS IDH1R132H HCT116 CELLS AGAINST IRRADIATION by Molenaar, R. J., Dimitrakopoulou, D., Stap, J., Bleeker, F. E., Van Noorden, C. J. F.

“…BACKGROUND: IDH1R132H mutations are both inaugural events in the formation of glioma and associated with prolonged glioma patient survival. The IDH1R132H…”
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Engineering the microflora to vaccinate the mucosa: serum immunoglobulin G responses and activated draining cervical lymph nodes following mucosal application of tetanus toxin fragment C‐expressing lactobacilli by Shaw, D. M., GaerthÉ, B., Leer, R. J., Van Der Stap, J. G. M. M., Smittenaar, C., Heijne Den Bak‐Glashouwer, M.‐J., Thole, J. E. R., Tielen, F. J., Pouwels, P. H., Havenith, C. E. G.

“…Summary The delivery of antigens to mucosal‐associated lymphoid tissues in paediatric and immunocompromised populations by safe, non‐invasive vectors, such as…”
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Dynamics of three-dimensional replication patterns during the S-phase, analysed by double labelling of DNA and confocal microscopy by MANDERS, E. M. M, STAP, J, BRAKENHOFF, G. J, VAN DRIEL, R, ATEN, J. A

“…The temporal and spatial progression of DNA replication in interphase nuclei of eukaryotic cells has been investigated. Application of a recently developed…”
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Quantitative determination of the reduction of phototoxicity and photobleaching by controlled light exposure microscopy by HOEBE, R.A, VAN DER VOORT, H.T.M, STAP, J, VAN NOORDEN, C.J.F, MANDERS, E.M.M

“…Phototoxicity and photobleaching are major limitations in live-cell fluorescence microscopy. They are caused by fluorophores in an excited singlet or triplet…”
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Clustering of double strand break-containing chromosome domains is not inhibited by inactivation of major repair proteins by Krawczyk, P. M., Stap, J., van Oven, C., Hoebe, R., Aten, J. A.

“…For efficient repair of DNA double strand breaks (DSBs) cells rely on a process that involves the Mre11/Rad50/Nbs1 complex, which may help to protect…”
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Dynamic Behavior of DNA Replication Domains by Manders, E.M.M., Stap, J., Strackee, J., van Driel, R., Aten, J.A.

“…Like many nuclear processes, DNA replication takes place in distinct domains that are scattered throughout the S-phase nucleus. Recently we have developed a…”
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PD-0669 Feasibility and first results of the trials-within-cohorts design in patients with lung cancer by Tomassen, M., Damen, P., Verkooijen, H., Peters, M., van der Stap, J., van Lindert, A., Verhoeff, J., van Rossum, P.

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Difference in sperm head volume as a theoretical basis for sorting X- and Y-bearing spermatozoa: Potentials and limitations by van Munster, E.B., Stap, J., Hoebe, R.A., te Meerman, G.J., Aten, J.A.

“…Volume-based sorting of X- and Y-chromosome-bearing sperm cells could be an interesting alternative to the existing technique based on DNA content. Advantages…”
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Induction and detection of bystander effects after combined treatment of cells with 5-bromo-2′-deoxyurine, Hoechst 33 258 and ultraviolet A light by Xiao, Y., De feyter, E., Van oven, C. H., Stap, J., Hoebe, R., Havenith, S., Van noorden, C. J. F., Aten, J. A.

“…Purpose: A combined treatment of cells with 5-bromo-2′-deoxyurine (BrdU), Hoechst 33 258 and ultraviolet A (UVA) light was used to introduce chromosomal…”
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Induction of chromosome aberrations in unirradiated chromatin after partial irradiation of a cell nucleus by Ludwików, G., Xiao, Yun, Hoebe, R. A., Franken, N. A. P., Darroudi, F., Stap, J., Oven, C. H. Van, Noorden, C. J. F. Van, Aten, J. A.

“…Purpose : It is generally accepted that chromosome exchanges in irradiated cells are formed through interactions between separate DNA double-strand breaks…”
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Patient reported outcomes during immunotherapy: Symptom burden in daily clinical practice by Koldenhof, J.J., Verberne, E.G., Verheijden, R.J., Tonk, E., van der Baan, F.H., van Lindert, A., van der Stap, J., Teunissen, S.C., Witteveen, P.O., Suijkerbuijk, K.P.M.

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CN72 - Patient reported outcomes during immunotherapy: Symptom burden in daily clinical practice by Koldenhof, J.J., Verberne, E.G., Verheijden, R.J., Tonk, E., van der Baan, F.H., van Lindert, A., van der Stap, J., Teunissen, S.C., Witteveen, P.O., Suijkerbuijk, K.P.M.

“…PD(L)1-inhibitors can cause immune-related adverse events (irAEs.). IrAEs may be under-recognized and their influence on health-related quality of life (HRQL)…”
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CN72Patient reported outcomes during immunotherapy: Symptom burden in daily clinical practice by Koldenhof, J J, Verberne, E G, Verheijden, R J, Tonk, E, van der Baan, F H, van Lindert, A, van der Stap, J, Teunissen, S C, Witteveen, P O, Suijkerbuijk, K P M

“…Abstract Background PD(L)1-inhibitors can cause immune-related adverse events (irAEs.). IrAEs may be under-recognized and their influence on health-related…”
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