Search Results - "Stanton, Alice E"
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Biochemical Ligand Density Regulates Yes-Associated Protein Translocation in Stem Cells through Cytoskeletal Tension and Integrins
Published in ACS applied materials & interfaces (06-03-2019)“…Different tissue types are characterized by varying stiffness and biochemical ligands. Increasing substrate stiffness has been shown to trigger Yes-associated…”
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Journal Article -
2
Extracellular matrix type modulates mechanotransduction of stem cells
Published in Acta biomaterialia (15-09-2019)“…[Display omitted] Extracellular matrix (ECM) is comprised of different types of proteins, which change in composition and ratios during morphogenesis and…”
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Journal Article -
3
Varying solvent type modulates collagen coating and stem cell mechanotransduction on hydrogel substrates
Published in APL bioengineering (01-09-2019)“…Type I collagen is the most abundant extracellular matrix protein in the human body and is commonly used as a biochemical ligand for hydrogel substrates to…”
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Journal Article -
4
Negative Transpulmonary Pressure Disrupts Airway Morphogenesis by Suppressing Fgf10
Published in Frontiers in cell and developmental biology (01-12-2021)“…Mechanical forces are increasingly recognized as important determinants of cell and tissue phenotype and also appear to play a critical role in organ…”
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Journal Article -
5
Hydrogels with enhanced protein conjugation efficiency reveal stiffness-induced YAP localization in stem cells depends on biochemical cues
Published in Biomaterials (01-05-2019)“…Polyacrylamide hydrogels have been widely used in stem cell mechanotransduction studies. Conventional conjugation methods of biochemical cues to polyacrylamide…”
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Journal Article -
6
Aligned Gelatin Microribbon Scaffolds with Hydroxyapatite Gradient for Engineering the Bone-Tendon Interface
Published in Tissue engineering. Part A (01-08-2022)“…Injuries of the bone-to-tendon interface, such as rotator cuff and anterior cruciate ligament tears, are prevalent musculoskeletal injuries, yet effective…”
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Journal Article -
7
Engineering multicellular living systems—a Keystone Symposia report
Published in Annals of the New York Academy of Sciences (01-12-2022)“…The ability to engineer complex multicellular systems has enormous potential to inform our understanding of biological processes and disease and alter the drug…”
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Journal Article -
8
Biochemical Ligand Density Regulates YAP Translocation in Stem Cells through Cytoskeletal Tension and Integrins
Published in ACS applied materials & interfaces (21-02-2019)“…Different tissue types are characterized by varying stiffness and biochemical ligands. Increasing substrate stiffness has been shown to trigger Yes-associated…”
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Journal Article -
9
Uncovering the Role of Biochemical Ligands in Modulating Stem Cell Mechanotransduction and Differentiation: A Biomaterials-Based Approach
Published 01-01-2020“…The extracellular matrix (ECM) is comprised of different types of proteins and adhesive ligands, which change in composition and ratios during morphogenesis…”
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Dissertation