Search Results - "Stansborough, Romany"

Proteasome inhibitor-induced gastrointestinal toxicity by Stansborough, Romany L., Gibson, Rachel J.

“…PURPOSE OF REVIEWGastrointestinal toxicities are commonly reported following treatment with proteasome inhibitors. The first-generation proteasome inhibitor,…”
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Matrix metalloproteinase expression is altered in the small and large intestine following fractionated radiation in vivo by Stansborough, Romany L., Al-Dasooqi, Noor, Bateman, Emma H., Bowen, Joanne M., Keefe, Dorothy M. K., Logan, Richard M., Yeoh, Ann S. J., Yeoh, Eric E. K., Stringer, Andrea M., Gibson, Rachel J.

“…Purpose Radiotherapy-induced gut toxicity (RIGT) is associated with significant diarrhoea, pain and rectal bleeding. Matrix metalloproteinases (MMPs) have been…”
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Radiotherapy-induced gut toxicity: Involvement of matrix metalloproteinases and the intestinal microvasculature by Stansborough, Romany L., Al-dasooqi, Noor, Bateman, Emma H., Keefe, Dorothy M. K., Gibson, Rachel J.

“…Purpose To review the literature surrounding the involvement of the endothelium and matrix metalloproteinases (MMP) in radiotherapy-induced gut toxicity (RIGT)…”
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Vascular endothelial growth factor (VEGF), transforming growth factor beta (TGFβ), angiostatin, and endostatin are increased in radiotherapy-induced gastrointestinal toxicity by Stansborough, Romany L., Bateman, Emma H., Al-Dasooqi, Noor, Bowen, Joanne M., Wignall, Anthony, Keefe, Dorothy M., Yeoh, Ann S., Logan, Richard M., Yeoh, Eric E. K., Stringer, Andrea M., Gibson, Rachel J.

“…Purpose: Radiotherapy-induced gut toxicity (RIGT) is a debilitating effect of radiotherapy for cancer, often resulting in significant diarrhea and pain…”
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Potential safety concerns of TLR4 antagonism with irinotecan: a preclinical observational report by Coller, Janet K., Bowen, Joanne M., Ball, Imogen A., Wardill, Hannah R., van Sebille, Ysabella Z. A., Stansborough, Romany L., Lightwala, Zenab, Wignall, Anthony, Shirren, Joseph, Secombe, Kate, Gibson, Rachel J.

“…Purpose Irinotecan-induced gut toxicity is mediated in part by Toll-Like receptor 4 (TLR4) signalling. The primary purpose of this preclinical study was to…”
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Fractionated abdominal irradiation induces intestinal microvascular changes in an in vivo model of radiotherapy-induced gut toxicity by Stansborough, Romany L., Bateman, Emma H., Al-Dasooqi, Noor, Bowen, Joanne M., Keefe, Dorothy M. K., Yeoh, Ann S. J., Logan, Richard M., Yeoh, Eric E. K., Stringer, Andrea M., Gibson, Rachel J.

“…Purpose Radiotherapy-induced gut toxicity (RIGT) is associated with diarrhoea, pain and rectal bleeding and can occur as an acute or chronic toxicity. The…”
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Management of Mucositis During Chemotherapy: From Pathophysiology to Pragmatic Therapeutics by Van Sebille, Ysabella Z. A., Stansborough, Romany, Wardill, Hannah R., Bateman, Emma, Gibson, Rachel J., Keefe, Dorothy M.

“…Chemotherapy-induced mucositis is a common condition caused by the breakdown of the mucosal barrier. Symptoms can include pain, vomiting and diarrhoea, which…”
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Irinotecan disrupts tight junction proteins within the gut: Implications for chemotherapy-induced gut toxicity by Wardill, Hannah R, Bowen, Joanne M, Al-Dasooqi, Noor, Sultani, Masooma, Bateman, Emma, Stansborough, Romany, Shirren, Joseph, Gibson, Rachel J

“…Chemotherapy for cancer causes significant gut toxicity, leading to severe clinical manifestations and an increased economic burden. Despite much research,…”
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Mixed effects of caffeic acid phenethyl ester (CAPE) on joint inflammation, bone loss and gastrointestinal inflammation in a murine model of collagen antibody-induced arthritis by Williams, Bonnie, Tsangari, Eleni, Stansborough, Romany, Marino, Victor, Cantley, Melissa, Dharmapatni, Anak, Gibson, Rachel, Perilli, Egon, Crotti, Tania

“…Objective To investigate the effect of caffeic acid phenethyl ester (CAPE) on local and systemic inflammation and bone loss in collagen antibody-induced…”
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