Search Results - "Stanley, Mathew"
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Structural basis for RING-Cys-Relay E3 ligase activity and its role in axon integrity
Published in Nature chemical biology (01-11-2020)“…MYCBP2 is a ubiquitin (Ub) E3 ligase (E3) that is essential for neurodevelopment and regulates axon maintenance. MYCBP2 transfers Ub to nonlysine substrates…”
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Probes of ubiquitin E3 ligases enable systematic dissection of parkin activation
Published in Nature chemical biology (01-05-2016)“…Probes of E3 ligase transthiolation activity reveal the hierarchy of phosphorylation events leading to cellular parkin activation and show that disease-linked…”
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3
Age-Related Compensatory Reconfiguration of PFC Connections during Episodic Memory Retrieval
Published in Cerebral cortex (New York, N.Y. 1991) (05-01-2021)“…Abstract During demanding cognitive tasks, older adults (OAs) frequently show greater prefrontal cortex (PFC) activity than younger adults (YAs). This…”
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Age-related differences in recognition in associative memory
Published in Aging, Neuropsychology, and Cognition (03-03-2020)“…Aging is often accompanied by associative memory changes, although their precise nature remains unclear. This study examines how recognition of item position…”
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Orthogonal Thiol Functionalization at a Single Atomic Center for Profiling Transthiolation Activity of E1 Activating Enzymes
Published in ACS chemical biology (19-06-2015)“…Transthiolation is a fundamental biological reaction and is utilized by many enzymes involved in the conjugation of ubiquitin and ubiquitin-like proteins…”
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Discrimination of normal, benign, and malignant breast tissues by Raman spectroscopy
Published in Biopolymers (05-12-2006)“…Breast cancers are the leading cancers among females. Diagnosis by fine needle aspiration cytology (FNAC) is the gold standard. The widely practiced screening…”
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Granular Cell Tumour of Breast-An Enigmatic Entity-Case Report with Emphasis on Role of Frozen Section
Published in Journal of clinical and diagnostic research (01-04-2018)“…Granular Cell Tumour (GCT) is a rare tumour involving the breast, pre- and intraoperative diagnosis of which plays an important role in deciding the treatment…”
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Discrimination of normal and malignant mucosal tissues of the colon by Raman spectroscopy
Published in Photomedicine and laser surgery (01-08-2007)“…The objective of this study was to evaluate the applicability of the discrimination parameters Mahalanobis distance, spectral residuals, and limit tests,…”
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9
Smoking and Thromboangitis Obliterans- Are they related ?
Published in Journal of Nepal Medical Association (01-04-2014)“…In 1908 Leo Buerger first gave the world the clinical picture of this dreadful disease which he called Thromboangitis Obliterans. Virtually all investigators…”
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10
Genetically Directed Production of Recombinant, Isosteric and Nonhydrolysable Ubiquitin Conjugates
Published in Chembiochem : a European journal of chemical biology (03-08-2016)“…We describe the genetically directed incorporation of aminooxy functionality into recombinant proteins by using a mutant Methanosarcina barkeri pyrrolysyl‐tRNA…”
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Chemical ubiquitination for decrypting a cellular code
Published in Biochemical journal (15-05-2016)“…The modification of proteins with ubiquitin (Ub) is an important regulator of eukaryotic biology and deleterious perturbation of this process is widely linked…”
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Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity
Published in Nature (London) (01-04-2018)“…Ubiquitination is initiated by transfer of ubiquitin (Ub) from a ubiquitin-activating enzyme (E1) to a ubiquitin-conjugating enzyme (E2), producing a…”
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13
Quality of Life among Cancer Patients
Published in Indian journal of palliative care (01-10-2017)“…Cancer is a leading cause of death. People living with cancer experience a variety of symptoms. Quality of life (QOL) is a major concern of patients with…”
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14
Genetic validation of Aspergillus fumigatus phosphoglucomutase as a viable therapeutic target in invasive aspergillosis
Published in The Journal of biological chemistry (01-06-2022)“…Aspergillus fumigatus is the causative agent of invasive aspergillosis, an infection with mortality rates of up to 50%. The glucan-rich cell wall of…”
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15
Specialist nurse initiated interventions in breast cancer care: A systematic review of randomised controlled trials
Published in Journal of clinical nursing (01-07-2020)“…Aims and objectives To evaluate the effectiveness of specialist nurse interventions in the care of women with breast cancer. Background Nurses perform a…”
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16
Targeting a critical step in fungal hexosamine biosynthesis
Published in The Journal of biological chemistry (26-06-2020)“…Aspergillus fumigatus is a human opportunistic fungal pathogen whose cell wall protects it from the extracellular environment including host defenses. Chitin,…”
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A Randomized controlled trial to evaluate the impact of a Nurse Navigator Programme on outcomes of people with breast cancer: study protocol
Published in Journal of advanced nursing (01-04-2017)“…Aim To evaluate the effectiveness of a Nurse Navigator Programme on anxiety, psychological distress and quality of life in people with breast cancer…”
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Probes of Ubiquitin E3 ligases distinguish different stages of Parkin activation
Published in Nature chemical biology (07-03-2016)“…E3 ligases represent an important class of enzymes, yet there are currently no chemical probes to profile their activity. We develop a new class of…”
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19
Jack in the box: inguinal endometriosis
Published in BMJ case reports (31-03-2015)“…A 39-year-old woman with a left-sided inguinal swelling was referred to us with a diagnosis of inguinal hernia. On asking leading questions, the patient gave a…”
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A Prospective Randomized Controlled Trial Comparing Clinical Equivalence of PD Synth and PDS Polydioxanone Sutures
Published in Curēus (Palo Alto, CA) (10-12-2023)“…Introduction Incisional hernia is a common complication of midline laparotomy that may develop even after several years of surgery. Abdominal fascia closure…”
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