Search Results - "Stanley, Elise F"

The Nanophysiology of Fast Transmitter Release by Stanley, Elise F

“…Action potentials invading the presynaptic terminal trigger discharge of docked synaptic vesicles (SVs) by opening voltage-dependent calcium channels (CaVs)…”
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PresyNaptic Calcium Channels: Why Is P Selected before N? by Stanley, Elise F.

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Single calcium channel domain gating of synaptic vesicle fusion at fast synapses; analysis by graphic modeling by Stanley, Elise F

“…At fast-transmitting presynaptic terminals Ca 2+ enter through voltage gated calcium channels (CaVs) and bind to a synaptic vesicle (SV) -associated calcium…”
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A small-molecule screen in C. elegans yields a new calcium channel antagonist by Roy, Peter J, Kwok, Trevor C. Y, Ricker, Nicole, Fraser, Regina, Chan, Allen W, Burns, Andrew, Stanley, Elise F, McCourt, Peter, Cutler, Sean R

“…Small-molecule inhibitors of protein function are powerful tools for biological analysis and can lead to the development of new drugs. However, a major…”
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N-type Ca2+ channels carry the largest current: implications for nanodomains and transmitter release by Weber, Alexander M, Wong, Fiona K, Tufford, Adele R, Schlichter, Lyanne C, Matveev, Victor, Stanley, Elise F

“…The established conductance hierarchy of voltage-gated calcium channels, where conductance of Ca V 1 is greater than Ca V 2, which is in turn greater than Ca V…”
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Rab3a interacting molecule (RIM) and the tethering of pre-synaptic transmitter release site-associated CaV2.2 calcium channels by Wong, Fiona K, Stanley, Elise F

“…Biochemical and physiological evidence suggest that pre-synaptic calcium channels are attached to the transmitter release site within the active zone by a…”
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Synaptic vesicle tethering and the CaV2.2 distal C-terminal by Wong, Fiona K, Nath, Arup R, Chen, Robert H C, Gardezi, Sabiha R, Li, Qi, Stanley, Elise F

“…Evidence that synaptic vesicles (SVs) can be gated by a single voltage sensitive calcium channel (CaV2.2) predict a molecular linking mechanism or "tether"…”
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Synaptic vesicle capture by CaV2.2 calcium channels by Wong, Fiona K, Li, Qi, Stanley, Elise F

“…The fusion of synaptic vesicles (SVs) at the presynaptic transmitter release face is gated by Ca(2) (+) influx from nearby voltage-gated calcium channels…”
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The Ca2+ release-activated Ca2+ current (ICRAC) mediates store-operated Ca2+ entry in rat microglia by Ohana, Lily, Newell, Evan W., Stanley, Elise F., Schlichter, Lyanne C.

“…Ca 2+ signaling plays a central role in microglial activation, and several studies have demonstrated a store-operated Ca 2+ entry (SOCE) pathway to supply this…”
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The presynaptic CaV2.2 channel-transmitter release site core complex by Khanna, Rajesh, Li, Qi, Bewersdorf, Joerg, Stanley, Elise F.

“…CaV2.2 channels play a key role in the gating of transmitter release sites (TRS) at presynaptic terminals. Physiological studies predict that the channels are…”
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Molecular Characterization of an SV Capture Site in the Mid-Region of the Presynaptic CaV2.1 Calcium Channel C-Terminal by Snidal, Christine A, Li, Qi, Elliott, Brittany B, Mah, Henry K-H, Chen, Robert H C, Gardezi, Sabiha R, Stanley, Elise F

“…Neurotransmitter is released from presynaptic nerve terminals at fast-transmitting synapses by the action potential-gating of voltage dependent calcium…”
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Cryoloading: introducing large molecules into live synaptosomes by Nath, Arup R, Chen, Robert H C, Stanley, Elise F

“…Neurons communicate with their target cells primarily by the release of chemical transmitters from presynaptic nerve terminals. The study of CNS presynaptic…”
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A proteomic screen for presynaptic terminal N-type calcium channel (CaV2.2) binding partners by Khanna, Rajesh, Zougman, Alexandre, Stanley, Elise F

“…N type calcium channels (CaV2.2) play a key role in the gating of transmitter release at presynaptic nerve terminals. These channels are generally regarded as…”
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'Fractional recovery' analysis of a presynaptic synaptotagmin 1-anchored endocytic protein complex by Khanna, Rajesh, Li, Qi, Stanley, Elise F

“…The integral synaptic vesicle protein and putative calcium sensor, synaptotagmin 1 (STG), has also been implicated in synaptic vesicle (SV) recovery. However,…”
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Syntaxin I modulation of presynaptic calcium channel inactivation revealed by botulinum toxin C1 by Stanley, Elise F.

“…The chick ciliary ganglion calyx‐type nerve terminal was used to examine voltage‐sensitive inactivation of presynaptic N‐type Ca2+ channels and to test if this…”
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Inter-channel scaffolding of presynaptic CaV2.2 via the C terminal PDZ ligand domain by Gardezi, Sabiha R, Li, Qi, Stanley, Elise F

“…Calcium entry through CaV2.2 calcium channels clustered at the active zone (AZ) of the presynaptic nerve terminal gates synaptic vesicle (SV) fusion and the…”
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Conserved biophysical features of the CaV2 presynaptic Ca2+ channel homologue from the early-diverging animal Trichoplax adhaerens by Gauberg, Julia, Abdallah, Salsabil, Elkhatib, Wassim, Harracksingh, Alicia N., Piekut, Thomas, Stanley, Elise F., Senatore, Adriano

“…The dominant role of CaV2 voltage-gated calcium channels for driving neurotransmitter release is broadly conserved. Given the overlapping functional properties…”
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Reversed Na+/Ca2+ Exchange Contributes to Ca2+ Influx and Respiratory Burst in Microglia by Newell, Evan W., Stanley, Elise F., Schlichter, Lyanne C.

“…Phagocytosis and the ensuing NADPH-mediated respiratory burst are important aspects of microglial activation that require calcium ion (Ca 2+ ) influx. However,…”
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Transglial transmission at the dorsal root ganglion sandwich synapse: glial cell to postsynaptic neuron communication by Rozanski, Gabriela M., Li, Qi, Stanley, Elise F.

“…The dorsal root ganglion (DRG) contains a subset of closely‐apposed neuronal somata (NS) separated solely by a thin satellite glial cell (SGC) membrane septum…”
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Munc18: A Presynaptic Transmitter Release Site N type (CaV2.2) Calcium Channel Interacting Protein by Chan, Allen W., Khanna, Rajesh, Li, Qi, Stanley, Elise F.

“…Munc18 is a presynaptic protein that is essential for transmitter release. Recent studies have indicated that this protein is involved in secretory vesicle…”
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