Search Results - "Stanilova, Spaska A."

The Role of Transforming Growth Factor-β1 Gene Polymorphism and Its Serum Levels in Hashimoto's Thyroiditis by Stanilova, Spaska A, Gerenova, Julieta B, Miteva, Lyuba D, Manolova, Irena M

“…TGF-β1 gene (TGFB1) is one of the target genes involved in genetic predisposition to autoimmune diseases, particularly Hashimoto's thyroiditis (HT). In the…”
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Cognitive Impairment in Multiple Sclerosis by Trenova, Anastasiya G, Slavov, Georgi S, Manova, Maria G, Aksentieva, Jana B, Miteva, Lyuba D, Stanilova, Spaska A

“…Multiple sclerosis (MS) is a socially significant immune-mediated disease, characterized by demyelination, axonal transection and oligodendropathy in the…”
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Increased transforming growth factor β and interleukin 10 transcripts in peripheral blood mononuclear cells of colorectal cancer patients by Stanilov, Noyko S, Miteva, Lyuba, Cirovski, Geo, Stanilova, Spaska A

“…The ability of immune cells in peripheral blood to produce certain cytokines affects tumour-elicited inflammation. The aim of this study was to investigate the…”
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A Role of Cytokine Gene Polymorphisms in Cognitive Functioning by Trenova, Anastasiya G, Slavov, Georgi S, Manova, Maria G, Miteva, Lyuba D, Stanilova, Spaska A

“…The changes in cognitive functions that occur with aging and in various pathological conditions are a subject of growing interest. Experimental and clinical…”
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Association of polymorphism -308G/A in tumor necrosis factor-alpha gene (TNF-α) and TNF-α serum levels in patients with relapsing-remitting multiple sclerosis by Grigorova, Antonia A., Trenova, Anastasiya G., Stanilova, Spaska A.

“…TNF-α is an important cytokine of the inflammatory response involved in the pathogenesis of relapsing-remitting multiple sclerosis (RRMS). The aim of this…”
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High interleukin-18 and low FOXP3 mRNAs in peripheral blood of women with severe systemic lupus erythematosus: a cross-sectional study by Miteva, Lyuba D., Manolova, Irena M., Ivanova, Mariana G., Stoilov, Rumen M., Stanilova, Spaska A.

“…Gene expression analysis of peripheral blood cells may provide valuable information about the triggered molecular processes in systemic lupus erythematosus…”
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Significance of −1082A/G polymorphism of IL10 gene for progression of colorectal cancer and IL-10 expression by Miteva, Lyuba D., Stanilov, Noyko S., Deliysky, Tashko S., Stanilova, Spaska A.

“…The role of functional polymorphism within IL10 (rs1800896) in colorectal cancer (CRC) still remains elusive. The aim of present study was to investigate the…”
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Functional relevance of IL-10 promoter polymorphisms for sepsis development by Stanilova, Spaska A

“…The induced production of proinflammatory and anti-inflammatory cytokines is considered important for the development of sepsis and its sequelae. Polymorphisms…”
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Interleukin‐10‐1082A/G polymorphism is associated with renal parenchymal damage in congenital anomalies of the kidney and urinary tract by Miteva, Lyuba D, Kostadinova, Emilya S, Stanilova, Spaska A

“…ABSTRACT Aim The aim of the study was to investigate whether the functional IL10‐1082A/G polymorphism exert a role in congenital anomalies of the kidney and…”
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Circulating levels of interleukin-17A, tumor necrosis factor-alpha, interleukin-18, interleukin-10, and cognitive performance of patients with relapsing-remitting multiple sclerosis by Trenova, Anastasiya G., Slavov, Georgi S., Draganova-Filipova, Milena N., Mateva, Nonka G., Manova, Mariya G., Miteva, Lyuba D., Stanilova, Spaska A.

“…Multiple sclerosis (MS) is associated with cytokine imbalance and high rate (40-70%) of cognitive impairment. The objective of this study is to investigate the…”
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Interleukin-10-1082 promoter polymorphism in association with cytokine production and sepsis susceptibility by STANILOVA, Spaska A, MITEVA, Lyuba D, KARAKOLEV, Zhivko T, STEFANOV, Chavdar S

“…To investigate the -1082 (A/G) polymorphism in the promoter of the IL-10 gene in terms of IL-10 production from stimulated peripheral blood mononuclear cells…”
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Association of insulin-like growth factor-I receptor polymorphism with colorectal cancer development by Stanilov, Noyko S., Karakolev, Iliya A., Deliysky, Tashko S., Jovchev, Jovcho P., Stanilova, Spaska A.

“…The insulin-like growth factor (IGF) system plays a prominent role in the cancer development. The IGF-1 receptor (IGF-1R) and its associated signalling pathway…”
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Effect of a Small Selective Inhibitor of C-Jun N-Terminal Kinase on the Inducible mRNA Expression of Interleukin-6 and Interleukin-18 by Stanilova, Spaska A, Grigorov, Boncho G, Platikanova, Magdalena S, Dobreva, Zlatka G

“…The expression of many inducible genes, involved in cell growth and differentiation as cytokine genes are regulated by receptor-activated intracellular…”
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Monocytes expression of IL-12 related and IL-10 genes in association with development of colorectal cancer by Stanilov, Noyko S., Miteva, Lyuba D., Dobreva, Zlatka G., Jovchev, Jovcho P., Cirovski, Geo M., Stanilova, Spaska A.

“…The main regulator of anti-tumor immune response is the activity of monocytes, suggesting that the produced cytokines may have a prognostic role. This study…”
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Functional genetic polymorphisms in interleukin-12B gene in association with systemic lupus erythematosus by Miteva, Lyuba D., Manolova, Irena M., Ivanova, Mariana G., Rashkov, Rasho K., Stoilov, Rumen M., Gulubova, Maya V., Stanilova, Spaska A.

“…Genetic polymorphisms in cytokine genes, which influence gene expression, may have an important impact on SLE susceptibility and severity. The aim of this…”
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High interleukin 12 and low interleukin 10 production after in vitro stimulation detected in sepsis survivors by STANILOVA, Spaska A, KARAKOLEV, Zhivko T, DIMOV, Gospodin S, DOBREVA, Zlatka G, MITEVA, Lyuba D, SLAVOV, Emil S, STEFANOV, Chavdar S, STANILOV, Noyko S

“…To evaluate viability of isolated peripheral blood mononuclear cells (PBMC) and production of cytokines in vitro after stimulation as prognostic factors for…”
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C3 binding glycoprotein from Cuscuta europea induced different cytokine profiles from human PBMC compared to other plant and bacterial immunomodulators by Stanilova, Spaska A., Dobreva, Zlatka G., Slavov, Emil S., Miteva, Lyuba D.

“…The immunomodulatory properties of bioactive agents include the ability to induce cytokine production by the activated target cell. The effect of…”
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Immunomodulatory effects of C3bgp on the antibody response to hemocyanin in outbred rabbits and the F1 generation of breeding with siblings by Stanilova, Spaska A., Miteva, Lyuba D., Tanchev, Svetlin G.

“…Dynamics and quantitative analyses of monospecific antibody during the primary and secondary humoral responses were determined in outbred rabbits and in the F1…”
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Interleukin‐10‐1082 A/G polymorphism is associated with renal parenchymal damage in congenital anomalies of the kidney and urinary tract by Miteva, Lyuba D, Kostadinova, Emilya S, Stanilova, Spaska A

“…ABSTRACT Aim The aim of the study was to investigate whether the functional IL10‐1082A/G polymorphism exert a role in congenital anomalies of the kidney and…”
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Cytokine production in thromboangiitis obliterans patients : New evidence for an immune-mediated inflammatory disorder by SLAVOV, E. S, STANILOVA, S. A, PETKOV, D. P, DOBREVA, Z. G

“…To study IL-6, IL-10, IL-12 levels and circulating immune complexes (CIC) containing IgG, IgM or IgA in sera of 14 TAO patients and 12 healthy blood donors. To…”
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