Search Results - "Stange, D. E."

Expression of an ASCL2 related stem cell signature and IGF2 in colorectal cancer liver metastases with 11p15.5 gain by Stange, D E, Engel, F, Longerich, T, Koo, B K, Koch, M, Delhomme, N, Aigner, M, Toedt, G, Schirmacher, P, Lichter, P, Weitz, J, Radlwimmer, B

“…Liver metastases are the leading cause of death in colorectal cancer. To gain better insight into the biology of metastasis and possibly identify new…”
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Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling by de Lau, Wim, Barker, Nick, Low, Teck Y., Koo, Bon-Kyoung, Li, Vivian S. W., Teunissen, Hans, Kujala, Pekka, Haegebarth, Andrea, Peters, Peter J., van de Wetering, Marc, Stange, D. E., van Es, J., Guardavaccaro, Daniele, Schasfoort, Richard B. M., Mohri, Yasuaki, Nishimori, Katsuhiko, Mohammed, Shabaz, Heck, Albert J. R., Clevers, Hans

“…The adult stem cell marker Lgr5 and its relative Lgr4 are often co-expressed in Wnt-driven proliferative compartments. We find that conditional deletion of…”
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Lgr6 Marks Stem Cells in the Hair Follicle That Generate All Cell Lineages of the Skin by Snippert, Hugo J, Haegebarth, Andrea, Kasper, Maria, Jaks, Viljar, van Es, Johan H, Barker, Nick, van de Wetering, Marc, van den Born, Maaike, Begthel, Harry, Vries, Robert G, Stange, Daniel E, Toftgård, Rune, Clevers, Hans

“…Mammalian epidermis consists of three self-renewing compartments: the hair follicle, the sebaceous gland, and the interfollicular epidermis. We generated…”
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Transcription Factor Achaete Scute-Like 2 Controls Intestinal Stem Cell Fate by van der Flier, Laurens G., van Gijn, Marielle E., Hatzis, Pantelis, Kujala, Pekka, Haegebarth, Andrea, Stange, Daniel E., Begthel, Harry, van den Born, Maaike, Guryev, Victor, Oving, Irma, van Es, Johan H., Barker, Nick, Peters, Peter J., van de Wetering, Marc, Clevers, Hans

“…The small intestinal epithelium is the most rapidly self-renewing tissue of mammals. Proliferative cells are confined to crypts, while differentiated cell…”
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A Chromosome 8 Gene-Cluster Polymorphism with Low Human Beta-Defensin 2 Gene Copy Number Predisposes to Crohn Disease of the Colon by Fellermann, Klaus, Stange, Daniel E., Schaeffeler, Elke, Schmalzl, Hartmut, Wehkamp, Jan, Bevins, Charles L., Reinisch, Walter, Teml, Alexander, Schwab, Matthias, Lichter, Peter, Radlwimmer, Bernhard, Stange, Eduard F.

“…Defensins are endogenous antimicrobial peptides that protect the intestinal mucosa against bacterial invasion. It has been suggested that deficient defensin…”
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Genomic and Protein Expression Profiling Identifies CDK6 As Novel Independent Prognostic Marker in Medulloblastoma by MENDRZYK, Frank, RADLWIMMER, Bernhard, KORSHUNOV, Andrey, LICHTER, Peter, JOOS, Stefan, KOKOCINSKI, Felix, BENNER, Axel, STANGE, Daniel E, NEBEN, Kai, FIEGLER, Heike, CARTER, Nigel P, REIFENBERGER, Guido

“…Medulloblastoma is the most common malignant brain tumor in children. Despite multimodal aggressive treatment, nearly half of the patients die as a result of…”
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Detection of chromosomal imbalances in retinoblastoma by matrix-based comparative genomic hybridization by Zielinski, Boris, Gratias, Sandrine, Toedt, Grischa, Mendrzyk, Frank, Stange, Daniel E., Radlwimmer, Bernhard, Lohmann, Dietmar R., Lichter, Peter

“…The genetic hallmark of retinoblastoma is mutation or deletion of the RB1 gene, whereas other genetic alterations that are also required are largely unknown…”
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High-Resolution Genomic Profiling Reveals Association of Chromosomal Aberrations on 1q and 16p with Histologic and Genetic Subgroups of Invasive Breast Cancer by STANGE, Daniel E, RADLWIMMER, Bernhard, LICHTER, Peter, SCHUBERT, Falk, TRAUB, Frank, PICH, Andreas, TOEDT, Grischa, MENDRZYK, Frank, LEHMANN, Ulrich, EILS, Roland, KREIPE, Hans

“…Purpose: Invasive ductal carcinoma and invasive lobular carcinoma (ILC) represent the major histologic subtypes of invasive breast cancer. They differ with…”
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Chirurgische Therapie von Adenokarzinomen des gastroösophagealen Übergangs und des Magens by Stange, D. E., Weitz, J., Welsch, T.

“…Zusammenfassung Jährlich erkranken weltweit gut eine Million Menschen an Karzinomen des Magens sowie des gastroösophagealen Übergangs („adenocarcinomas of the…”
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