Search Results - "Stanford, Janet L"
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Metformin use and prostate cancer in Caucasian men: results from a population-based case-control study
Published in Cancer causes & control (01-11-2009)“…Purpose Metformin is a commonly used medication for type II diabetes mellitus. Epidemiologic studies have suggested a decreased relative risk of cancer with…”
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Long-Term Functional Outcomes after Treatment for Localized Prostate Cancer
Published in The New England journal of medicine (31-01-2013)“…In this study involving 1655 men who had been treated for localized prostate cancer, differences between prostatectomy and radiotherapy were noted in the first…”
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A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer
Published in Nature genetics (01-10-2014)“…Rosalind Eeles, Christopher Haiman and colleagues report genome-wide association and meta-analyses of prostate cancer in populations of European, African,…”
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4
Treatment Decision Regret Among Long-Term Survivors of Localized Prostate Cancer: Results From the Prostate Cancer Outcomes Study
Published in Journal of clinical oncology (10-07-2017)“…Purpose To determine the demographic, clinical, decision-making, and quality-of-life factors that are associated with treatment decision regret among long-term…”
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Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array
Published in Nature genetics (01-04-2013)“…Rosalind Eeles and colleagues report meta-analysis of genome-wide association studies for prostate cancer and genotyping on the custom iCOGS array in 25,074…”
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6
DNA methylation and cis-regulation of gene expression by prostate cancer risk SNPs
Published in PLoS genetics (30-03-2020)“…Genome-wide association studies have identified more than 100 SNPs that increase the risk of prostate cancer (PrCa). We identify and compare expression…”
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Biallelic BRCA2 Mutations Shape the Somatic Mutational Landscape of Aggressive Prostate Tumors
Published in American journal of human genetics (05-05-2016)“…To identify clinically important molecular subtypes of prostate cancer (PCa), we characterized the somatic landscape of aggressive tumors via deep,…”
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Discovery and fine-mapping of adiposity loci using high density imputation of genome-wide association studies in individuals of African ancestry: African Ancestry Anthropometry Genetics Consortium
Published in PLoS genetics (21-04-2017)“…Genome-wide association studies (GWAS) have identified >300 loci associated with measures of adiposity including body mass index (BMI) and waist-to-hip ratio…”
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Identification of seven new prostate cancer susceptibility loci through a genome-wide association study
Published in Nature genetics (01-10-2009)“…Rosalind Eeles and colleagues present a genome-wide association study for prostate cancer. They report seven loci newly associated with prostate cancer…”
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10
Detection of differentially methylated CpGs between tumour and adjacent benign cells in diagnostic prostate cancer samples
Published in Scientific reports (02-08-2024)“…Differentially methylated CpG sites (dmCpGs) that distinguish prostate tumour from adjacent benign tissue could aid in the diagnosis and prognosis of prostate…”
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Testing the circadian gene hypothesis in prostate cancer: a population-based case-control study
Published in Cancer research (Chicago, Ill.) (15-12-2009)“…Circadian genes are responsible for maintaining the ancient adaptation of a 24-hour circadian rhythm and influence a variety of cancer-related biological…”
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12
Genome-wide association study of prostate cancer in men of African ancestry identifies a susceptibility locus at 17q21
Published in Nature genetics (01-06-2011)“…Christopher Haiman and colleagues report a genome-wide association study for prostate cancer in African-American males drawn from 11 epidemiological studies of…”
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13
Expression of SLCO Transport Genes in Castration-Resistant Prostate Cancer and Impact of Genetic Variation in SLCO1B3 and SLCO2B1 on Prostate Cancer Outcomes
Published in Cancer epidemiology, biomarkers & prevention (01-04-2011)“…Metastases from men with castration-resistant prostate cancer (CRPC) harbor increased tumoral androgens versus untreated prostate cancers. This may reflect…”
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14
Genetic predisposition to prostate cancer: Update and future perspectives
Published in Urologic oncology (01-02-2015)“…Abstract Objective Prostate cancer is the second most frequent cancer in men worldwide and kills over 250,000 men worldwide every year. Prostate cancer is a…”
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15
Epigenomic profiling of DNA methylation in paired prostate cancer versus adjacent benign tissue
Published in The Prostate (01-12-2015)“…Background Aberrant DNA methylation may promote prostate carcinogenesis. We investigated epigenome‐wide DNA methylation profiles in prostate cancer (PCa)…”
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Statin Use in Relation to Prostate Cancer Outcomes in a Population-based Patient Cohort Study
Published in The Prostate (01-08-2013)“…BACKGROUND We investigated associations between statin use begun before prostate cancer (PCa) diagnosis and PCa recurrence/progression and PCa‐specific…”
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Influence of Age on Incident Diabetes and Cardiovascular Disease in Prostate Cancer Survivors Receiving Androgen Deprivation Therapy
Published in The Journal of urology (01-04-2015)“…Purpose Observational data suggest that androgen deprivation therapy increases the risk of diabetes and cardiovascular disease. Using data from the population…”
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5-year urinary and sexual outcomes after radical prostatectomy: results from the prostate cancer outcomes study
Published in The Journal of urology (01-05-2005)“…Prior studies of postoperative outcomes following radical prostatectomy have been limited by selection bias and short-term followup. In this study we assessed…”
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Characterizing genetic risk at known prostate cancer susceptibility loci in African Americans
Published in PLoS genetics (01-05-2011)“…GWAS of prostate cancer have been remarkably successful in revealing common genetic variants and novel biological pathways that are linked with its etiology. A…”
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HOXB13 mutations in a population-based, case-control study of prostate cancer
Published in The Prostate (01-05-2013)“…BACKGROUND Prostate cancer (PC) is the most frequently diagnosed non‐skin malignancy in men in the Western world, yet few disease‐associated mutations have…”
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