Search Results - "Stanek, Aleksandra"
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Neurobiological Basis of Increased Risk for Suicidal Behaviour
Published in Cells (Basel, Switzerland) (23-09-2021)“…According to the World Health Organization (WHO), more than 700,000 people die per year due to suicide. Suicide risk factors include a previous suicide attempt…”
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Is leucodystrophy really a feature of PIGT‐CDG?
Published in Neuropathology and applied neurobiology (01-10-2020)Get full text
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Sex-Related Predisposition to Post-Traumatic Stress Disorder Development-The Role of Neuropeptides
Published in International journal of environmental research and public health (01-01-2022)“…Post-traumatic stress disorder (PTSD) is characterized by re-experiencing a traumatic event, avoidance, negative alterations in cognitions and mood,…”
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The role of the dorsal hippocampus in resistance to the development of posttraumatic stress disorder-like behaviours
Published in Behavioural brain research (13-02-2023)“…This study aimed to determine the activity of the dorsal hippocampus (dHIP) in resistance to the development of posttraumatic stress disorder (PTSD)-like…”
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The effect of valproate on the amino acids, monoamines, and kynurenic acid concentrations in brain structures involved in epileptogenesis in the pentylenetetrazol-kindled rats
Published in Pharmacological reports (01-04-2024)“…The study aimed to assess the influence of a single valproate (VPA) administration on inhibitory and excitatory neurotransmitter concentrations in the brain…”
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The effect of chronic administration of corticosterone on anxiety- and depression-like behavior and the expression of GABA-A receptor alpha-2 subunits in brain structures of low- and high-anxiety rats
Published in Hormones and behavior (01-01-2014)“…The aim of this study was to examine changes in rat emotional behavior and determine differences in the expression of GABA-A receptor alpha-2 subunits in brain…”
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Individual susceptibility or resistance to posttraumatic stress disorder-like behaviours
Published in Behavioural brain research (27-05-2020)“…•Selection for resistant PTSD(-) and susceptible PTSD(+) rats based on fear response.•PTSD(+) rats had decreased plasma corticosterone level.•PTSD(+) rats had…”
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Changes in the brain expression of alpha-2 subunits of the GABA-A receptor after chronic restraint stress in low- and high-anxiety rats
Published in Behavioural brain research (15-09-2013)“…•Chronic restraint stress decreased high anxiety rats (HR) activity in Porsolt test.•HR restraint rats had decreased alpha-2 GABA-A receptors density in…”
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Behavioral effects and CRF expression in brain structures of high- and low-anxiety rats after chronic restraint stress
Published in Behavioural brain research (01-09-2016)“…•Chronic restraint increased immobility in Porsolt test in high anxiety rats (HR).•Chronic restraint increased anxiety of HR rats in the open field…”
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Evidence of the milder phenotypic spectrum of c.1582G>A PIGT variant: Delineation based on seven novel Polish patients
Published in Clinical genetics (01-11-2020)“…PIGT is one of over 29 glycosylphosphatidylinositol biosynthesis defect genes. Mutations cause genetically determined disorders characterized mainly by…”
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FGF12p.Gly112Ser variant as a cause of phenytoin/phenobarbital responsive epilepsy
Published in Clinical genetics (01-09-2019)“…A patient harboring a novel p.Gly112Ser variant in FGF12 gene had a positive response to phenytoin/phenobarbital treatment. All the 11 previously reported…”
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The role of UCH-L1, MMP-9, and GFAP as peripheral markers of different susceptibility to seizure development in a preclinical model of epilepsy
Published in Journal of neuroimmunology (15-07-2019)“…In our study, we assessed the potency of the brain-derived proteins ubiquitin carboxy-terminal hydrolase L1 (UCH-L1), matrix metalloproteinase 9 (MMP-9), glial…”
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A rat model to study maternal depression during pregnancy and postpartum periods, its comorbidity with cardiovascular diseases and neurodevelopmental impact in the offspring
Published in Physiology & behavior (01-02-2019)“…This study aimed to develop an animal model of human depression during pregnancy and lactation to examine the effect of maternal, perinatal depression on…”
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Clinical heterogeneity of polish patients with KAT6B–related disorder
Published in Molecular genetics & genomic medicine (01-12-2023)“…Background Say‐Barber‐Biesecker‐Young‐Simpson (SBBYSS) variant of Ohdo syndrome is a rare, autosomal dominant and clinically heterogenous disorder, caused by…”
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The remarkable phenotypic variability of the p.Arg269HiS variant in the TRPV4 gene
Published in Muscle & nerve (01-01-2019)“…ABSTRACT Introduction: Mutations in the TRPV4 gene are associated with neuromuscular disorders and skeletal dysplasias, which present a phenotypic overlap…”
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Novel COL12A1 variant as a cause of mild familial extracellular matrix‐related myopathy
Published in Clinical genetics (01-06-2019)Get full text
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Stress changes amphetamine response, D2 receptor expression and epigenetic regulation in low-anxiety rats
Published in Progress in neuro-psychopharmacology & biological psychiatry (13-07-2019)“…The aim of this study was to assess the influence of chronic restraint stress on amphetamine (AMPH)-related appetitive 50-kHz ultrasonic vocalisations (USVs)…”
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Pulmonary involvement in selected lysosomal storage diseases and the impact of enzyme replacement therapy: A state-of-the art review
Published in The clinical respiratory journal (01-05-2020)“…Lysosomal storage disorders (LSDs) are multisystemic, progressive and clinically very heterogeneous. Respiratory complications are not regarded as the…”
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Molecular pattern of a decrease in the rewarding effect of cocaine after an escalating-dose drug regimen
Published in Pharmacological reports (01-02-2023)“…Long-term cocaine exposure leads to dysregulation of the reward system and initiates processes that ultimately weaken its rewarding effects. Here, we studied…”
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