Search Results - "Stampfli, H F"

Biochemical properties of blood esmolol esterase by Quon, C Y, Stampfli, H F

“…The blood esterase mediating the hydrolysis of esmolol was characterized in several different species including man. In contrast to most ester-containing…”
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Species differences in the stereoselective hydrolysis of esmolol by blood esterases by Quon, C Y, Mai, K, Patil, G, Stampfli, H F

“…The stereoselective hydrolysis of esmolol was examined in blood from several species including humans. Blood esmolol esterase activity was in the order of…”
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Pharmacokinetics of the inodilator XB513 in mice, rats, guinea pigs, rabbits, dogs, and monkeys by Stampfli, H F, Person, C R, Huang, S M, Quon, C Y

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Biochemical characterization of flestolol esterase by Quon, C Y, Stampfli, H F

“…The blood esterase that mediates the metabolism of flestolol, an ultra short-acting beta blocker, was characterized. Esterase activity occurred in plasma of…”
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Tissue distribution of N-acetylprocainamide in rats by Yacobi, A, Stampfli, H F, Lai, C M, Kamath, B L

“…The purpose of this study was to determine the distribution of N-acetylprocainamide (NAPA) in heart, kidney, and liver tissues of rats and their relationship…”
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High-performance liquid chromatographic assay for the major blood metabolite of esmolol--an ultra short acting beta blocker by Stampfli, H F, Lai, C M, Yacobi, A, Sum, C Y

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Age-related pharmacokinetics of N-acetylprocainamide in rats by Yacobi, A, Kamath, B L, Stampfli, H F, Look, Z M, Lai, C M

“…The pharmacokinetics of N-acetylprocainamide, administered orally or intravenously, were studied in 3-, 6-, and 12-month-old rats using a two-way crossover…”
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An evaluation of 2-benzyl-1-naphthol (DuP 654) analogs as systemic anti-inflammatory agents by Kerr, J S, Batt, D G, Pinto, D J, Stampfli, H F

“…DuP 654 (2-benzyl-1-naphthol) is a topically active anti-inflammatory agent that was evaluated in phase II clinical trials as an anti-psoriatic agent. The…”
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Mouse endogenous spleen counts as a means of screening for anti-radiation drugs by Kinnamon, K E, Ketterling, L L, Stampfli, H F, Grenan, M M

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Survival of Bone Marrow-Engrafted Mice Subsequent to Protection from Lethal Radiation by WR 2721 by Kinnamon, Kenneth E., Ketterling, Lyle L., Ledney, G. David, Lorenz, Gregory B., Mioduszewski, Robert J., Stampfli, Herman F.

“…For the first time data are presented for animals treated with bone marrow cells after lethal radiation exposure while protected with WR 2721 (the single…”
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Polymorphic metabolism of flestolol and other ester containing compounds by a carboxylesterase in New Zealand white rabbit blood and cornea by Stampfli, H F, Quon, C Y

“…Flestolol, N(1,1-dimethyl-2-ureidocthyl)-2-hydroxy-3-(o-fluorobenzoyloxy++ +) propylamine, (F), is an ester containing an ultra short-acting beta blocker…”
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Ester derivatives of 2,6-bis(1-pyrrolidinylmethyl)-4-benzamidophenol as short-acting antiarrhythmic agents. 1 by Stout, David M, Black, Lawrence A, Barcelon-Yang, Cynthia, Matier, W. L, Brown, Barry S, Quon, Check Y, Stampfli, Herman F

“…In an effort to find a replacement for the iv antiarrhythmic drug lidocaine having reduced systemic and central nervous system effects, activity against…”
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[(Arylcarbonyl)oxy]propanolamines. 1. Novel .beta.-blockers with ultrashort duration of action by Kam, Sheung Tsam, Matier, William L, Mai, Khuong X, Barcelon-Yang, Cynthia, Borgman, Robert J, O'Donnell, John P, Stampfli, Herman F, Sum, Check Y, Anderson, William G

“…Novel [(arylcarbonyl)oxy]propanolamines were synthesized and investigated as potential ultrashort-acting beta-adrenergic receptor blockers. Many of these…”
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Mono- and bis(aminomethyl)phenylacetic acid esters as short-acting antiarrhythmic agents. II by CHORVAT, R. J, BLACK, L. A, RANADE, V. V, BARCELON-YANG, C, STOUT, D. M, BROWN, B. S, STAMPFLI, H. F, QUON, C. Y

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Mono- and bis(aminomethyl)phenylacetic acid esters as short-acting antiarrhythmic agents. 2 by Chorvat, Robert J, Black, Lawrence A, Ranade, Vasant V, Barcelon-Yang, Cynthia, Stout, David M, Brown, Barry S, Stampfli, Herman F, Quon, Check Y

“…The synthesis, antiarrhythmic activity, and blood hydrolysis properties of a series of mono- and bis(aminomethyl)phenylacetic acid esters related to a…”
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Ester derivatives of 2,6-bis(1-pyrrolidinylmethyl)-4-benzamidophenol as short-acting antiarrhythmic agents. I by STOUT, D. M, BLACK, L. A, BARCELON-YANG, C, MATIER, W. L, BROWN, B. S, QUON, C. Y, STAMPFLI, H. F

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Pharmacodynamics and onset of action of esmolol in anesthetized dogs by Quon, C Y, Gorczynski, R J

“…The pharmacodynamics and onset of action of esmolol, a novel, cardioselective beta adrenergic receptor antagonist with an ultra short duration of action, were…”
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[(Arylcarbonyl) oxy] propanolamines. I: Novel β-blockers with ultrashort duration of action by SHEUNG-TSAM KAM, MATIER, W. L, LEE, R. J, MAI, K. X, BARCELON-YANG, C, BORGMAN, R. J, O'DONNELL, J. P, STAMPFLI, H. F, SUM, C. Y, ANDERSON, W. G, GORCZYNSKI, R. J

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Tissue distribution of [14C]bretylium tosylate in rats by Yacobi, A, Kamath, B L, Lai, C M, Stampfli, H F

“…The distribution of [14C]bretylium tosylate in the body and the relationship between tissue and plasma concentrations was determined following intravenous…”
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Pharmacokinetics of [14C]bretylium tosylate in rats by Kamath, B L, Stampfli, H F, Lai, C M, Yacobi, A

“…The pharmacokinetics of bretylium tosylate were investigated in eight male Charles River rats. Each animal received an intravenous dose (10 mg/kg) of…”
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