Search Results - "Stamatos, Nicholas M"

Polysialylation controls immune function of myeloid cells in murine model of pneumococcal pneumonia by Shinde, Prajakta, Kiepas, Alexander, Zhang, Lei, Sudhir, Shreya, Konstantopoulos, Konstantinos, Stamatos, Nicholas M.

“…Polysialic acid (polySia) is a post-translational modification of a select group of cell-surface proteins that guides cellular interactions. As the overall…”
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Polysialylated Neuropilin-2 Is Expressed on the Surface of Human Dendritic Cells and Modulates Dendritic Cell-T Lymphocyte Interactions by Curreli, Sabrina, Arany, Zita, Gerardy-Schahn, Rita, Mann, Dean, Stamatos, Nicholas M.

“…Polysialic acid (PSA) is a unique linear homopolymer of α2,8-linked sialic acid that has been identified as a posttranslational modification on only five…”
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LPS-induced cytokine production in human dendritic cells is regulated by sialidase activity by Stamatos, Nicholas M., Carubelli, Ivan, Vlekkert, Diantha, Bonten, Erik J., Papini, Nadia, Feng, Chiguang, Venerando, Bruno, dˈAzzo, Alessandra, Cross, Alan S., Wang, Lai‐Xi, Gomatos, Peter J.

“…Neu1 and Neu3 are up‐regulated as monocytes differentiate into DCs; and desialylation of cell surface glycoconjugates by one or both sialidase promotes…”
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Monocyte Differentiation Up-regulates the Expression of the Lysosomal Sialidase, Neu1, and Triggers Its Targeting to the Plasma Membrane via Major Histocompatibility Complex Class II-positive Compartments by Liang, Feng, Seyrantepe, Volkan, Landry, Karine, Ahmad, Rasheed, Ahmad, Ali, Stamatos, Nicholas M., Pshezhetsky, Alexey V.

“…Human sialidase (neuraminidase) Neu1 catalyzes lysosomal catabolism of sialylated glycoconjugates. Here we show that during the differentiation of monocytes…”
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Changes in polysialic acid expression on myeloid cells during differentiation and recruitment to sites of inflammation: role in phagocytosis by Stamatos, Nicholas M, Zhang, Lei, Jokilammi, Anne, Finne, Jukka, Chen, Wilbur H, El-Maarouf, Abderrahman, Cross, Alan S, Hankey, Kim G

“…Polysialic acid (polySia) is a unique linear homopolymer of α2,8-linked sialic acid that has been studied extensively as a posttranslational modification of…”
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Sialidase expression in activated human T lymphocytes influences production of IFN-γ by Nan, Xinli, Carubelli, Ivan, Stamatos, Nicholas M.

“…Sialidases influence cellular activity by removing terminal sialic acid from glycoproteins and glycolipids. Four genetically distinct sialidases (Neu1–4) have…”
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Sialyl residues modulate LPS-mediated signaling through the Toll-like receptor 4 complex by Feng, Chiguang, Stamatos, Nicholas M, Dragan, Anatoliy I, Medvedev, Andrei, Whitford, Melissa, Zhang, Lei, Song, Chang, Rallabhandi, Prasad, Cole, Leah, Nhu, Quan M, Vogel, Stefanie N, Geddes, Chris D, Cross, Alan S

“…We previously reported that neuraminidase (NA) pretreatment of human PBMCs markedly increased their cytokine response to lipopolysaccharide (LPS). To study the…”
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Toward a Carbohydrate-Based HIV-1 Vaccine:  Synthesis and Immunological Studies of Oligomannose-Containing Glycoconjugates by Ni, Jiahong, Song, Haijing, Wang, Yadong, Stamatos, Nicholas M, Wang, Lai-Xi

“…Human antibody 2G12 is a broadly neutralizing antibody that exerts its anti-HIV activity by targeting a novel oligomannose cluster on HIV-1 gp120. It was…”
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Class 3 semaphorins induce F‐actin reorganization in human dendritic cells: Role in cell migration by Curreli, Sabrina, Wong, Bin Sheng, Latinovic, Olga, Konstantopoulos, Konstantinos, Stamatos, Nicholas M.

“…Class 3 Sema signal through NRP and plexin coreceptors in human DCs to induce actin reorganization and promote cellular migration. Class 3 semaphorins (Semas)…”
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Expression of sialyltransferase activity on intact human neutrophils by Rifat, Salahaldin, Kang, Tae Jin, Mann, Dean, Zhang, Lei, Puche, Adam C., Stamatos, Nicholas M., Goldblum, Simeon E., Brossmer, Reinhard, Cross, Alan S.

“…Endogenous polymorphonuclear leukocyte (PMN)‐associated sialidase activity enhances PMN adhesion to and migration across the endothelium through the removal of…”
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Desialylation of glycoconjugates on the surface of monocytes activates the extracellular signal-related kinases ERK 1/2 and results in enhanced production of specific cytokines by Stamatos, Nicholas M., Curreli, Sabrina, Zella, Davide, Cross, Alan S.

“…Modulation of the sialic acid content of cell‐surface glycoproteins and glycolipids influences the functional capacity of cells of the immune system. The role…”
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Differential expression of endogenous sialidases of human monocytes during cellular differentiation into macrophages by Stamatos, Nicholas M., Liang, Feng, Nan, Xinli, Landry, Karine, Cross, Alan S., Wang, Lai‐Xi, Pshezhetsky, Alexey V.

“…Sialidases are enzymes that influence cellular activity by removing terminal sialic acid from glycolipids and glycoproteins. Four genetically distinct…”
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Mobilization of neutrophil sialidase activity desialylates the pulmonary vascular endothelial surface and increases resting neutrophil adhesion to and migration across the endothelium by Sakarya, Serhan, Rifat, Salahaldin, Zhou, Jie, Bannerman, Douglas D., Stamatos, Nicholas M., Cross, Alan S., Goldblum, Simeon E.

“…The amount of sialic acid on the surface of the neutrophil (PMN) influences its ability to interact with other cells. PMN activation with various stimuli…”
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Neutralizing Antibodies from the Sera of Human Immunodeficiency Virus Type 1-Infected Individuals Bind to Monomeric gp120 and Oligomeric gp140 by Stamatos, N M, Mascola, J R, Kalyanaraman, V S, Louder, M K, Frampton, L M, Birx, D L, VanCott, T C

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Desialylation of Peripheral Blood Mononuclear Cells Promotes Growth of HIV-1 by Stamatos, Nicholas M, Gomatos, Peter J, Cox, Josephine, Fowler, Arnold, Dow, Nancy, Wohlhieter, John A, Cross, Alan S

“…Activation of peripheral blood CD4+helper T lymphocytes establishes a permissive state for growth of HIV-1. Activated T lymphocytes expressed increased…”
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Desialylation of TLR4/MD2/CD14 enhances the response to LPS (135.16) by Feng, Chiguang, Whitford, Melissa, Zhang, Lei, Rallabhandi, Prasad, Vogel, Stefanie N., Stamatos, Nicholas M.

“…Abstract Objective: Since bacterial neuraminidase (NANase) treatment of intact human PBMCs led to a synergistic increase in cytokine expression, we…”
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Small Reovirus Particles Composed Solely of Sigma NS with Specificity for Binding Different Nucleic Acids by Gomatos, Peter J., Prakash, Om, Stamatos, Nicholas M.

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Relative inefficiency of soluble recombinant CD4 for inhibition of infection by monocyte-tropic HIV in monocytes and T cells by Gomatos, PJ, Stamatos, NM, Gendelman, HE, Fowler, A, Hoover, DL, Kalter, DC, Burke, DS, Tramont, EC, Meltzer, MS

“…Macrophages are major viral reservoirs in the brain, lungs, and lymph nodes of HIV-infected patients. But not all HIV isolates infect macrophages. The…”
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Binding to Selected Regions of Reovirus mRNAs by a Nonstructural Reovirus Protein by Stamatos, Nicholas M., Gomatos, Peter J.

“…When assembled into 13-19S particles, the reovirus nonstructural protein σ -NS selectively binds single-stranded RNAs. Sedimentation analyses combined with…”
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