Search Results - "Stamatopoulos, K."

Marginal zone lymphomas: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up by Zucca, E., Arcaini, L., Buske, C., Johnson, P.W., Ponzoni, M., Raderer, M., Ricardi, U., Salar, A., Stamatopoulos, K., Thieblemont, C., Wotherspoon, A., Ladetto, M.

“…•This updated ESMO Clinical Practice Guideline provides key recommendations on the management of marginal zone lymphomas.•Authorship includes a…”
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Antigen receptor stereotypy in chronic lymphocytic leukemia by Stamatopoulos, K, Agathangelidis, A, Rosenquist, R, Ghia, P

“…The discovery of almost identical or ‘stereotyped’ B-cell receptor immunoglobulins (BcR IG) among unrelated patients with chronic lymphocytic leukemia (CLL)…”
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ERIC recommendations for TP53 mutation analysis in chronic lymphocytic leukemia—update on methodological approaches and results interpretation by Malcikova, J., Tausch, E., Rossi, D., Sutton, L. A., Soussi, T., Zenz, T., Kater, A. P., Niemann, C. U., Gonzalez, D., Davi, F., Gonzalez Diaz, M., Moreno, C., Gaidano, G., Stamatopoulos, K., Rosenquist, R., Stilgenbauer, S., Ghia, P., Pospisilova, S.

“…In chronic lymphocytic leukemia (CLL), TP53 gene defects, due to deletion of the 17p13 locus and/or mutation(s) within the TP53 gene, are associated with…”
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Microenvironmental influences in chronic lymphocytic leukaemia: the role of antigen stimulation by Ghia, P., Chiorazzi, N., Stamatopoulos, K.

“… Several studies suggest that immune‐mediated pathways are important in the pathogenesis of chronic lymphocytic leukaemia (CLL). The in vivo accumulation of…”
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Immunoglobulin gene sequence analysis in chronic lymphocytic leukemia: updated ERIC recommendations by Rosenquist, R, Ghia, P, Hadzidimitriou, A, Sutton, L-A, Agathangelidis, A, Baliakas, P, Darzentas, N, Giudicelli, V, Lefranc, M-P, Langerak, A W, Belessi, C, Davi, F, Stamatopoulos, K

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Prognostic indices in chronic lymphocytic leukaemia: where do we stand how do we proceed? by Baliakas, P., Mattsson, M., Stamatopoulos, K., Rosenquist, R.

“…The remarkable clinical heterogeneity in chronic lymphocytic leukaemia (CLL) has highlighted the need for prognostic and predictive algorithms that can be…”
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The duality between particle methods and artificial neural networks by Alexiadis, A., Simmons, M. J. H., Stamatopoulos, K., Batchelor, H. K., Moulitsas, I.

“…The algorithm behind particle methods is extremely versatile and used in a variety of applications that range from molecular dynamics to astrophysics. For…”
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Development of a digital twin of a tablet that mimics a real solid dosage form: Differences in the dissolution profile in conventional mini-USP II and a biorelevant colon model by Schütt, M., Stamatopoulos, K., Batchelor, H.K., Simmons, M.J.H., Alexiadis, A.

“…The performance of colon-targeted solid dosage forms is commonly assessed using standardised pharmacopeial dissolution apparatuses like the USP II or the…”
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High-Throughput Sequencing of the T-Cell Receptor Beta Chain Gene Repertoire in Chronic Lymphocytic Leukemia by Vlachonikola, E, Vardi, A, Stamatopoulos, K, Hadzidimitriou, A

“…High-throughput, next-generation sequencing (NGS) offers a unique opportunity for in-depth characterization of adaptive immune receptor repertoires…”
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Publisher Correction: The duality between particle methods and artificial neural networks by Alexiadis, A., Simmons, M. J. H., Stamatopoulos, K., Batchelor, H. K., Moulitsas, I.

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Restrictions in the T-cell repertoire of chronic lymphocytic leukemia: high-throughput immunoprofiling supports selection by shared antigenic elements by Vardi, A, Vlachonikola, E, Karypidou, M, Stalika, E, Bikos, V, Gemenetzi, K, Maramis, C, Siorenta, A, Anagnostopoulos, A, Pospisilova, S, Maglaveras, N, Chouvarda, I, Stamatopoulos, K, Hadzidimitriou, A

“…Immunoglobulin (IG) gene repertoire restrictions strongly support antigen selection in the pathogenesis of chronic lymphocytic leukemia (CLL). Given the…”
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Modelling and simulation of the hydrodynamics and mixing profiles in the human proximal colon using Discrete Multiphysics by Schütt, M., Stamatopoulos, K., Simmons, M.J.H., Batchelor, H.K., Alexiadis, A.

“…The proximal part of the colon offers opportunities to prolong the absorption window following oral administration of a drug. In this work, we used computer…”
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Corrigendum to “Marginal zone lymphomas: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up”: [Annals of Oncology 31 (2020) 17–29] by Zucca, E., Arcaini, L., Buske, C., Johnson, P.W., Ponzoni, M., Raderer, M., Ricardi, U., Salar, A., Stamatopoulos, K., Thieblemont, C., Wotherspoon, A., Ladetto, M.

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The virtual physiological human gets nerves! How to account for the action of the nervous system in multiphysics simulations of human organs by Alexiadis, A, Simmons, M J H, Stamatopoulos, K, Batchelor, H K, Moulitsas, I

“…This article shows how to couple multiphysics and artificial neural networks to design computer models of human organs that autonomously adapt their behaviour…”
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Splenic marginal zone lymphoma proposals for a revision of diagnostic, staging and therapeutic criteria by Matutes, E, Oscier, D, Montalban, C, Berger, F, Callet-Bauchu, E, Dogan, A, Felman, P, Franco, V, Iannitto, E, Mollejo, M, Papadaki, T, Remstein, E D, Salar, A, Solé, F, Stamatopoulos, K, Thieblemont, C, Traverse-Glehen, A, Wotherspoon, A, Coiffier, B, Piris, M A

“…Since the initial description of splenic marginal zone lymphoma (SMZL) in 1992, an increasing number of publications have dealt with multiple aspects of SMZL…”
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Early stages in the ontogeny of small B‐cell lymphomas: genetics and microenvironment by Ghia, P., Nadel, B., Sander, B., Stamatopoulos, K., Stevenson, F. K.

“…In this review, we focus on the mechanisms underlying lymphomagenesis in chronic lymphocytic leukaemia, follicular lymphoma, mantle cell lymphoma and splenic…”
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ERIC recommendations on IGHV gene mutational status analysis in chronic lymphocytic leukemia by Ghia, P, Stamatopoulos, K, Belessi, C, Moreno, C, Stilgenbauer, S, Stevenson, F, Davi, F, Rosenquist, R

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EZH2 upregulates the PI3K/AKT pathway through IGF1R and MYC in clinically aggressive chronic lymphocytic leukaemia by Kosalai, Subazini Thankaswamy, Morsy, Mohammad Hamdy Abdelrazak, Papakonstantinou, Nikos, Mansouri, Larry, Stavroyianni, Niki, Kanduri, Chandrasekhar, Stamatopoulos, Kostas, Rosenquist, Richard, Kanduri, Meena

“…EZH2 is overexpressed in poor-prognostic chronic lymphocytic leukaemia (CLL) cases, acting as an oncogene; however, thus far, the EZH2 target genes in CLL have…”
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Clinical impact of recurrently mutated genes on lymphoma diagnostics: state-of-the-art and beyond by Rosenquist, Richard, Rosenwald, Andreas, Du, Ming-Qing, Gaidano, Gianluca, Groenen, Patricia, Wotherspoon, Andrew, Ghia, Paolo, Gaulard, Philippe, Campo, Elias, Stamatopoulos, Kostas

“…Similar to the inherent clinical heterogeneity of most, if not all, lymphoma entities, the genetic landscape of these tumors is markedly complex in the…”
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Distinct patterns of novel gene mutations in poor-prognostic stereotyped subsets of chronic lymphocytic leukemia: the case of SF3B1 and subset #2 by Strefford, J C, Sutton, L-A, Baliakas, P, Agathangelidis, A, Malčíková, J, Plevova, K, Scarfó, L, Davis, Z, Stalika, E, Cortese, D, Cahill, N, Pedersen, L B, di Celle, P F, Tzenou, T, Geisler, C, Panagiotidis, P, Langerak, A W, Chiorazzi, N, Pospisilova, S, Oscier, D, Davi, F, Belessi, C, Mansouri, L, Ghia, P, Stamatopoulos, K, Rosenquist, R

“…Recent studies have revealed recurrent mutations of the NOTCH1 , SF3B1 and BIRC3 genes in chronic lymphocytic leukemia (CLL), especially among aggressive,…”
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