Search Results - "Stamatakis, Alice M."

Activation of lateral habenula inputs to the ventral midbrain promotes behavioral avoidance by Stamatakis, Alice M, Stuber, Garret D

“…The projection from the lateral habenula (LHb) to the rostromedial tegmental nucleus (RMTg) transmits negative reward–related information. Here the authors…”
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Visualizing Hypothalamic Network Dynamics for Appetitive and Consummatory Behaviors by Jennings, Joshua H., Ung, Randall L., Resendez, Shanna L., Stamatakis, Alice M., Taylor, Johnathon G., Huang, Jonathan, Veleta, Katie, Kantak, Pranish A., Aita, Megumi, Shilling-Scrivo, Kelson, Ramakrishnan, Charu, Deisseroth, Karl, Otte, Stephani, Stuber, Garret D.

“…Optimally orchestrating complex behavioral states, such as the pursuit and consumption of food, is critical for an organism’s survival. The lateral…”
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The Inhibitory Circuit Architecture of the Lateral Hypothalamus Orchestrates Feeding by Jennings, Joshua H., Rizzi, Giorgio, Stamatakis, Alice M., Ung, Randall L., Stuber, Garret D.

“…The growing prevalence of overeating disorders is a key contributor to the worldwide obesity epidemic. Dysfunction of particular neural circuits may trigger…”
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Considerations when using cre-driver rodent lines for studying ventral tegmental area circuitry by Stuber, Garret D, Stamatakis, Alice M, Kantak, Pranish A

“…The use of Cre-driver rodent lines for targeting ventral tegmental area (VTA) cell types has generated important and novel insights into how precise…”
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Excitatory transmission from the amygdala to nucleus accumbens facilitates reward seeking by Stuber, Garret D., Sparta, Dennis R., Stamatakis, Alice M., van Leeuwen, Wieke A., Hardjoprajitno, Juanita E., Cho, Saemi, Tye, Kay M., Kempadoo, Kimberly A., Zhang, Feng, Deisseroth, Karl, Bonci, Antonello

“…Brain function during reward seeking Interactions between the basolateral amygdala (BLA) and nucleus accumbens (NAc) are involved in a number of…”
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A Unique Population of Ventral Tegmental Area Neurons Inhibits the Lateral Habenula to Promote Reward by Stamatakis, Alice M., Jennings, Joshua H., Ung, Randall L., Blair, Grace A., Weinberg, Richard J., Neve, Rachael L., Boyce, Frederick, Mattis, Joanna, Ramakrishnan, Charu, Deisseroth, Karl, Stuber, Garret D.

“…Lateral habenula (LHb) neurons convey aversive and negative reward conditions through potent indirect inhibition of ventral tegmental area (VTA) dopaminergic…”
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Construction of implantable optical fibers for long-term optogenetic manipulation of neural circuits by Sparta, Dennis R, Stamatakis, Alice M, Phillips, Jana L, Hovelsø, Nanna, van Zessen, Ruud, Stuber, Garret D

“…In vivo optogenetic strategies have redefined our ability to assay how neural circuits govern behavior. Although acutely implanted optical fibers have…”
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Amygdala and bed nucleus of the stria terminalis circuitry: Implications for addiction-related behaviors by Stamatakis, Alice M., Sparta, Dennis R., Jennings, Joshua H., McElligott, Zoe A., Decot, Heather, Stuber, Garret D.

“…Complex motivated behavioral processes, such as those that can go awry following substance abuse and other neuropsychiatric disorders, are mediated by a…”
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Simultaneous Optogenetics and Cellular Resolution Calcium Imaging During Active Behavior Using a Miniaturized Microscope by Stamatakis, Alice M, Schachter, Mike J, Gulati, Srishti, Zitelli, Kevin T, Malanowski, Sam, Tajik, Arash, Fritz, Christopher, Trulson, Mark, Otte, Stephani L

“…The ability to precisely monitor and manipulate neural circuits is essential to understand the brain. Advancements over the last decade in optical techniques…”
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Presynaptic Inhibition of Gamma-Aminobutyric Acid Release in the Bed Nucleus of the Stria Terminalis by Kappa Opioid Receptor Signaling by Li, Chia, Pleil, Kristen E, Stamatakis, Alice M, Busan, Steven, Vong, Linh, Lowell, Bradford B, Stuber, Garret D, Kash, Thomas L

“…Background The kappa opioid receptor (KOR) and its endogenous agonist, the neuropeptide dynorphin, are a critical component of the central stress system. Both…”
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Miniature microscopes for manipulating and recording in vivo brain activity by Stamatakis, Alice M, Resendez, Shanna L, Chen, Kai-Siang, Favero, Morgana, Liang-Guallpa, Jing, Nassi, Jonathan J, Neufeld, Shay Q, Visscher, Koen, Ghosh, Kunal K

“…Abstract Here we describe the development and application of miniature integrated microscopes (miniscopes) paired with microendoscopes that allow for the…”
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Loss of UBE3A from TH-expressing neurons suppresses GABA co-release and enhances VTA-NAc optical self-stimulation by Berrios, Janet, Stamatakis, Alice M., Kantak, Pranish A., McElligott, Zoe A., Judson, Matthew C., Aita, Megumi, Rougie, Marie, Stuber, Garret D., Philpot, Benjamin D.

“…Motivated reward-seeking behaviours are governed by dopaminergic ventral tegmental area projections to the nucleus accumbens. In addition to dopamine, these…”
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Inhibition of projections from the basolateral amygdala to the entorhinal cortex disrupts the acquisition of contextual fear by Sparta, Dennis R, Smithuis, Jim, Stamatakis, Alice M, Jennings, Joshua H, Kantak, Pranish A, Ung, Randall L, Stuber, Garret D

“…The development of excessive fear and/or stress responses to environmental cues such as contexts associated with a traumatic event is a hallmark of…”
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Lateral Hypothalamic Area Glutamatergic Neurons and Their Projections to the Lateral Habenula Regulate Feeding and Reward by Stamatakis, Alice M, Van Swieten, Maaike, Basiri, Marcus L, Blair, Grace A, Kantak, Pranish, Stuber, Garret D

“…The overconsumption of calorically dense, highly palatable foods is thought to be a major contributor to the worldwide obesity epidemic; however, the precise…”
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Distinct extended amygdala circuits for divergent motivational states by Jennings, Joshua H., Sparta, Dennis R., Stamatakis, Alice M., Ung, Randall L., Pleil, Kristen E., Kash, Thomas L., Stuber, Garret D.

“…Examination of the bed nucleus of the stria terminalis projections to the ventral tegmental area shows that glutamatergic and GABAergic projections have…”
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Developments from Bulk Optogenetics to Single-Cell Strategies to Dissect the Neural Circuits that Underlie Aberrant Motivational States by Rodriguez-Romaguera, Jose, Namboodiri, Vijay M K, Basiri, Marcus L, Stamatakis, Alice M, Stuber, Garret D

“…Motivational states are regulated by complex networks across brain regions that are composed of genetically and functionally distinct neuronal populations…”
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Optogenetic strategies to dissect the neural circuits that underlie reward and addiction by Stamatakis, Alice M, Stuber, Garret D

“…Optogenetic strategies for perturbation of neural circuit function have begun to revolutionize systems neuroscience. Whereas optogenetics has proven to be a…”
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Levetiracetam Has Opposite Effects on Alcohol- and Cocaine-Related Behaviors in C57BL/6J Mice by ROBINSON, J. Elliott, MENG CHEN, STAMATAKIS, Alice M, KROUSE, Michael C, HOWARD, Elaina C, FACCIDOMO, Sara, HODGE, Clyde W, FISH, Eric W, MALANGA, C. J

“…The antiepileptic drug levetiracetam (LEV) is a potential treatment for alcohol use disorders, yet few preclinical studies exist on its effects in animal…”
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Presynaptic inhibition of GABA release in the BNST by kappa opioid receptor signaling by Li, Chia, Pleil, Kristen E., Stamatakis, Alice M., Busan, Steven, Vong, Linh, Lowell, Bradford B., Stuber, Garret D., Kash, Thomas L.

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Amygdala to nucleus accumbens excitatory transmission facilitates reward seeking by Stuber, Garret D., Sparta, Dennis R., Stamatakis, Alice M., van Leeuwen, Wieke A., Hardjoprajitno, Juanita E., Cho, Saemi, Tye, Kay M., Kempadoo, Kimberly A., Zhang, Feng, Deisseroth, Karl, Bonci, Antonello

“…The basolateral amygdala (BLA) plays a crucial role in emotional learning irrespective of valence 1 – 5 . While the BLA projection to the nucleus accumbens…”
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