Search Results - "Stalpers, L J"

The alfa and beta of tumours: a review of parameters of the linear-quadratic model, derived from clinical radiotherapy studies by van Leeuwen, C M, Oei, A L, Crezee, J, Bel, A, Franken, N A P, Stalpers, L J A, Kok, H P

“…Prediction of radiobiological response is a major challenge in radiotherapy. Of several radiobiological models, the linear-quadratic (LQ) model has been best…”
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How can communication by oncologists enhance patients' trust? An experimental study by Hillen, M.A., de Haes, H.C.J.M., Stalpers, L.J.A., Klinkenbijl, J.H.G., Eddes, E.H., Butow, P.N., van der Vloodt, J., van Laarhoven, H.W.M., Smets, E.M.A.

“…Cancer patients need to trust their oncologist to embark in the process of oncologic treatment. Yet, it is unclear how oncologist communication contributes to…”
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Dosimetric comparison of library of plans and online MRI-guided radiotherapy of cervical cancer in the presence of intrafraction anatomical changes by Visser, J, de Boer, P, Crama, K F, van Kesteren, Z, Rasch, C R N, Stalpers, L J A, Bel, A

“…Online magnetic resonance imaging (MRI)-guided radiotherapy of cervical cancer has the potential to further reduce dose to organs at risk (OAR) as compared to…”
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Late neurocognitive sequelae in patients with WHO grade I meningioma by Dijkstra, M, van Nieuwenhuizen, D, Stalpers, L J A, Wumkes, M, Waagemans, M, Vandertop, W P, Heimans, J J, Leenstra, S, Dirven, C M, Reijneveld, J C, Klein, M

“…Background:Information on neurocognitive outcome following treatment of benign meningiomas is virtually lacking. This is remarkable considering that survival…”
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Bevacizumab and dose-intense temozolomide in recurrent high-grade glioma by Verhoeff, J.J.C., Lavini, C., van Linde, M.E., Stalpers, L.J.A., Majoie, C.B.L.M., Reijneveld, J.C., van Furth, W.R., Richel, D.J.

“…Angiogenesis inhibition is a rational treatment strategy for high-grade glioma (HGG). Combined antiangiogenic therapy and chemotherapy could be beneficial,…”
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Biological modelling of the radiation dose escalation effect of regional hyperthermia in cervical cancer by Crezee, J, van Leeuwen, C M, Oei, A L, van Heerden, L E, Bel, A, Stalpers, L J A, Ghadjar, P, Franken, N A P, Kok, H P

“…Locoregional hyperthermia combined with radiotherapy significantly improves locoregional control and overall survival for cervical tumors compared to…”
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Absence of the MGMT protein as well as methylation of the MGMT promoter predict the sensitivity for temozolomide by van Nifterik, K A, van den Berg, J, van der Meide, W F, Ameziane, N, Wedekind, L E, Steenbergen, R D M, Leenstra, S, Lafleur, M V M, Slotman, B J, Stalpers, L J A, Sminia, P

“…Background: The DNA repair protein O 6 -methylguanine-DNA methyltransferase (MGMT) can cause resistance to the alkylating drug temozolomide (TMZ). The purpose…”
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Molecular and biological rationale of hyperthermia as radio- and chemosensitizer by Oei, A.L., Kok, H.P., Oei, S.B., Horsman, M.R., Stalpers, L.J.A., Franken, N.A.P., Crezee, J.

“…Mild hyperthermia, local heating of the tumour up to temperatures <43 °C, has been clinically applied for almost four decades and has been proven to…”
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Radiation-enhanced vascular endothelial growth factor (VEGF) secretion in glioblastoma multiforme cell lines : a clue to radioresistance? by HOVINGA, K. E, STALPERS, L. J. A, VAN BREE, C, DONKER, M, VERHOEFF, J. J. C, RODERMOND, H. M, BOSCH, D. A, VAN FURTH, W. R

“…Postoperative radiotherapy is standard treatment for patients with a glioblastoma multiforme (GBM). However, a GBM is radioresistant and almost always recurs,…”
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Cisplatin-DNA adduct formation in patients treated with cisplatin-based chemoradiation: lack of correlation between normal tissues and primary tumor by Hoebers, F. J. P., Pluim, D., Hart, A. A. M., Verheij, M., Balm, A. J. M., Fons, G., Rasch, C. R. N., Schellens, J. H. M., Stalpers, L. J. A., Bartelink, H., Begg, A. C.

“…Purpose In this study, the formation of cisplatin-DNA adducts after concurrent cisplatin-radiation and the relationship between adduct-formation in primary…”
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[ 18 F]FDG-PET/CT-based risk stratification in women with locally advanced uterine cervical cancer by Adam, J A, Poel, E, van Eck Smit, B L F, Mom, C H, Stalpers, L J A, Laan, J J, Kidd, E, Stoker, J, Bipat, S

“…[ F]FDG-PET/CT is used for staging and treatment planning in patients with locally advanced cervical cancer (LACC). We studied if a PET-based prediction model…”
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The effect of time interval between radiotherapy and hyperthermia on planned equivalent radiation dose by van Leeuwen, C M, Crezee, J, Oei, A L, Franken, N A P, Stalpers, L J A, Bel, A, Kok, H P

“…Thermoradiotherapy is an effective treatment for locally advanced cervical cancer. However, the optimal time interval between radiotherapy and hyperthermia,…”
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Feasibility of on-line temperature-based hyperthermia treatment planning to improve tumour temperatures during locoregional hyperthermia by Kok, H P, Korshuize-van Straten, L, Bakker, A, de Kroon-Oldenhof, R, Westerveld, G H, Versteijne, E, Stalpers, L J A, Crezee, J

“…The effectiveness of hyperthermia is strongly dependent on the achieved tumour temperatures. Phased-array systems allow flexible power steering to realise good…”
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Measurement and analysis of the impact of time-interval, temperature and radiation dose on tumour cell survival and its application in thermoradiotherapy plan evaluation by van Leeuwen, C M, Oei, A L, Ten Cate, R, Franken, N A P, Bel, A, Stalpers, L J A, Crezee, J, Kok, H P

“…Biological modelling of thermoradiotherapy may further improve patient selection and treatment plan optimisation, but requires a model that describes the…”
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On verification of hyperthermia treatment planning for cervical carcinoma patients by van Haaren, P M A, Kok, H P, van den Berg, C A T, Zum Vörde Sive Vörding, P J, Oldenborg, S, Stalpers, L J A, Schilthuis, M S, de Leeuw, A A C, Crezee, J

“…The aim of this study was to verify hyperthermia treatment planning calculations by means of measurements performed during hyperthermia treatments. The…”
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Socioeconomic status as an independent risk factor for severe late bowel toxicity after primary radiotherapy for cervical cancer by Laan, J.J., van Lonkhuijzen, L.R.C.W., van Os, R.M., Tytgat, K.M., Dávila Fajardo, R., Pieters, B.R., Stalpers, L.J.A., Westerveld, G.H.

“…•1/8 women develop severe late bowel toxicity after radiotherapy for cervical cancer.•Severe late bowel toxicity occurs mostly within the first 3years after…”
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Long-term cervical cancer survivors suffer from pelvic floor symptoms: A cross-sectional matched cohort study by Hazewinkel, M.H, Sprangers, M.A.G, van der Velden, J, van der Vaart, C.H, Stalpers, L.J.A, Burger, M.P.M, Roovers, J.P.W.R

“…Abstract Objective The aim of this study was to determine prevalence of and experienced distress from pelvic floor symptoms in cervical cancer survivors (CCS)…”
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Repair of Potentially Lethal Damage does not Depend on Functional TP53 in Human Glioblastoma Cells by van Bree, C., Franken, N. A P., Rodermond, H. M., Stalpers, L. J A., Haveman, J.

“…van Bree, C., Franken, N. A. P., Rodermond, H. M., Stalpers, L. J. A. and Haveman, J. Repair of Potentially Lethal Damage does not Depend on Functional TP53 in…”
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Generic method for automatic bladder segmentation on cone beam CT using a patient-specific bladder shape model by van de Schoot, A. J. A. J., Schooneveldt, G., Wognum, S., Hoogeman, M. S., Chai, X., Stalpers, L. J. A., Rasch, C. R. N., Bel, A.

“…Purpose: The aim of this study is to develop and validate a generic method for automatic bladder segmentation on cone beam computed tomography (CBCT),…”
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Postoperative single-dose interstitial high–dose-rate brachytherapy in therapy-resistant keloids by Hafkamp, C.J.H, Lapid, O, Dávila Fajardo, R, van de Kar, A.L, Koedooder, C, Stalpers, L.J, Pieters, B.R

“…Abstract Purpose Patients with keloids complain of the cosmetic aspect, pain, and pruritus. Many different therapies are being used for keloids. The aim of…”
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