Search Results - "Stalnaker, Thomas"
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Neuroscience: A bottom-up mechanism for cognitive control?
Published in Current biology (05-08-2024)“…Cognitive control is often conceived of as occurring top-down, with prefrontal cortical areas exerting control over other parts of the brain. A new study…”
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What the orbitofrontal cortex does not do
Published in Nature neuroscience (01-05-2015)“…In the last 25 years, explosive interest has implicated the orbitofrontal cortex in nearly every function known to cognitive neuroscience. Yet scientific…”
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Neuroscience: Action history and the orbitofrontal cortex
Published in Current biology (07-11-2022)“…Decisions are often made in the absence of instructive cues, based instead on memories of previous actions and outcomes. A new study sheds light on how…”
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Orbitofrontal State Representations Are Related to Choice Adaptations and Reward Predictions
Published in The Journal of neuroscience (03-03-2021)“…Animals can categorize the environment into "states," defined by unique sets of available action-outcome contingencies in different contexts. Doing so helps…”
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A new perspective on the role of the orbitofrontal cortex in adaptive behaviour
Published in Nature reviews. Neuroscience (01-12-2009)“…The orbitofrontal cortex has a role in flexible behaviour. schoenbaum and colleagues discuss recent data suggesting that it signals expected outcomes and…”
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The impact of orbitofrontal dysfunction on cocaine addiction
Published in Nature neuroscience (01-03-2012)“…Here the authors review evidence suggesting that cocaine-induced changes in orbitofrontal cortex disrupt the representation of states and transition functions…”
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Cholinergic Interneurons Use Orbitofrontal Input to Track Beliefs about Current State
Published in The Journal of neuroscience (08-06-2016)“…When conditions change, organisms need to learn about the changed conditions without interfering with what they already know. To do so, they can assign the new…”
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Rat Orbitofrontal Ensemble Activity Contains Multiplexed but Dissociable Representations of Value and Task Structure in an Odor Sequence Task
Published in Current biology (18-03-2019)“…The orbitofrontal cortex (OFC) has long been implicated in signaling information about expected outcomes to facilitate adaptive or flexible behavior. Current…”
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How Did the Chicken Cross the Road? With Her Striatal Cholinergic Interneurons, Of Course
Published in Neuron (Cambridge, Mass.) (10-07-2013)“…Recognizing when the world changes is fundamental for normal learning. In this issue of Neuron, Bradfield et al. (2013) show that cholinergic interneurons in…”
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Orbitofrontal neurons signal reward predictions, not reward prediction errors
Published in Neurobiology of learning and memory (01-09-2018)“…•OFC neurons do not signal errors in the prediction of reward number or identity.•OFC neurons do signal predictions based on reward number or identity.•This…”
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Dopaminergic prediction errors in the ventral tegmental area reflect a multithreaded predictive model
Published in Nature neuroscience (01-05-2023)“…Dopamine neuron activity is tied to the prediction error in temporal difference reinforcement learning models. These models make significant simplifying…”
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Orbitofrontal neurons infer the value and identity of predicted outcomes
Published in Nature communications (04-06-2014)“…The best way to respond flexibly to changes in the environment is to anticipate them. Such anticipation often benefits us if we can infer that a change has…”
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Risk-Responsive Orbitofrontal Neurons Track Acquired Salience
Published in Neuron (Cambridge, Mass.) (23-01-2013)“…Decision making is impacted by uncertainty and risk (i.e., variance). Activity in the orbitofrontal cortex, an area implicated in decision making, covaries…”
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Optogenetic Inhibition of Rat Anterior Cingulate Cortex Impairs the Ability to Initiate and Stay on Task
Published in The Journal of neuroscience (15-05-2024)“…Our prior research has identified neural correlates of cognitive control in the anterior cingulate cortex (ACC), leading us to hypothesize that the ACC is…”
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Orbitofrontal cortex, decision-making and drug addiction
Published in Trends in neurosciences (Regular ed.) (01-02-2006)“…The orbitofrontal cortex, as a part of prefrontal cortex, is implicated in executive function. However, within this broad region, the orbitofrontal cortex is…”
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Neural substrates of cognitive inflexibility after chronic cocaine exposure
Published in Neuropharmacology (01-01-2009)“…Cognitive changes in addicts and animals exposed to addictive drugs have been extensively investigated over the past decades. One advantage of studying…”
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Basolateral Amygdala Lesions Abolish Orbitofrontal-Dependent Reversal Impairments
Published in Neuron (Cambridge, Mass.) (05-04-2007)“…Damage to orbitofrontal cortex (OFC) has long been associated with deficits in reversal learning. OFC damage also causes inflexible associative encoding in…”
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Dopamine neuron ensembles signal the content of sensory prediction errors
Published in eLife (01-11-2019)“…Dopamine neurons respond to errors in predicting value-neutral sensory information. These data, combined with causal evidence that dopamine transients support…”
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Prior Cocaine Use Alters the Normal Evolution of Information Coding in Striatal Ensembles during Value-Guided Decision-Making
Published in The Journal of neuroscience (13-01-2021)“…Substance use disorders (SUDs) are characterized by maladaptive behavior. The ability to properly adjust behavior according to changes in environmental…”
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The Orbitofrontal Cortex and Ventral Tegmental Area Are Necessary for Learning from Unexpected Outcomes
Published in Neuron (Cambridge, Mass.) (30-04-2009)“…Humans and other animals change their behavior in response to unexpected outcomes. The orbitofrontal cortex (OFC) is implicated in such adaptive responding,…”
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