Search Results - "Stallcup, W"

The NG2 proteoglycan promotes oligodendrocyte progenitor proliferation and developmental myelination by Kucharova, K, Stallcup, W.B

“…Abstract The NG2 proteoglycan has been shown to promote proliferation and motility in a variety of cell types. The presence of NG2 on oligodendrocyte…”
Get full text

The progenitor cell marker NG2 MPG promotes chemoresistance by activation of integrin-dependent PI3K Akt signaling by Chekenya, M, Krakstad, C, Svendsen, A, Netland, I A, Staalesen, V, Tysnes, B B, Selheim, F, Wang, J, Sakariassen, P Ø, Sandal, T, Lønning, P E, Flatmark, T, Enger, P Ø, Bjerkvig, R, Sioud, M, Stallcup, W B

“…Chemoresistance represents a major problem in the treatment of many malignancies. Overcoming this obstacle will require improved understanding of the…”
Get full text

NG2, a novel proapoptotic receptor, opposes integrin α4 to mediate anoikis through PKCα-dependent suppression of FAK phosphorylation by Joo, N E, Watanabe, T, Chen, C, Chekenya, M, Stallcup, W B, Kapila, Y L

“…Disruption of cell–matrix interactions can lead to anoikis – apoptosis due to loss of matrix contacts. Altered fibronectin (FN) induces anoikis of primary…”
Get full text

Co-localization of NG2 proteoglycan and PDGF α-receptor on O2A progenitor cells in the developing rat brain by Nishiyama, A., Lin, X.-H., Giese, N., Heldin, C.-H., Stallcup, W.B.

“…A detailed comparison in the developing rat central nervous system between the distribution of the NG2 proteoglycan and the α‐receptor for platelet‐derived…”
Get full text

NG2 proteoglycan-binding peptides target tumor neovasculature by BURG, M. A, PASQUALINI, R, ARAP, W, RUOSLAHTI, E, STALLCUP, W. B

“…NG2 is the rat homologue of the human melanoma proteoglycan, also known as the high molecular weight melanoma-associated antigen. This developmentally…”
Get full text

NG2 Is a Major Chondroitin Sulfate Proteoglycan Produced after Spinal Cord Injury and Is Expressed by Macrophages and Oligodendrocyte Progenitors by Jones, Leonard L, Yamaguchi, Yu, Stallcup, William B, Tuszynski, Mark H

“…Several extracellular matrix (ECM) molecules have been identified as potent inhibitors of neurite outgrowth in vitro and are believed to limit axonal growth…”
Get full text

Matrix Metalloproteinase-9 Facilitates Remyelination in Part by Processing the Inhibitory NG2 Proteoglycan by Larsen, Peter H, Wells, Jennifer E, Stallcup, William B, Opdenakker, Ghislain, Yong, V. Wee

“…Remyelination is a critical repair process that is initiated after a demyelinating insult. The failure to remyelinate contributes to neurological diseases such…”
Get full text

NG2 proteoglycan is expressed exclusively by mural cells during vascular morphogenesis by Ozerdem, Ugur, Grako, Kathryn A., Dahlin‐Huppe, Kimberlee, Monosov, Edward, Stallcup, William B.

“…Immunofluorescence mapping demonstrates that the NG2 proteoglycan is invariably expressed by the mural cell component of mouse neovascular structures. This…”
Get full text

NG2 proteoglycan expression in the peripheral nervous system: upregulation following injury and comparison with CNS lesions by Rezajooi, Kia, Pavlides, M, Winterbottom, J, Stallcup, W.B, Hamlyn, P.J, Lieberman, A.R, Anderson, P.N

“…The chondroitin sulphate proteoglycan NG2 blocks neurite outgrowth in vitro and thus may be able to inhibit axonal regeneration in the CNS. We have used…”
Get full text

An Anti-Angiogenic State in Mice and Humans with Retinal Photoreceptor Cell Degeneration by Lahdenranta, Johanna, Pasqualini, Renata, Schlingemann, Reinier O., Hagedorn, Martin, Stallcup, William B., Bucana, Corazon D., Sidman, Richard L., Arap, Wadih

“…Abnormal angiogenesis accompanies many pathological conditions including cancer, inflammation, and eye diseases. Proliferative retinopathy because of retinal…”
Get full text

Functional and morphological effects of NG2 proteoglycan deletion on hippocampal neurogenesis by Thallmair, Michaela, Ray, Jasodhara, Stallcup, William B., Gage, Fred H.

“…NG2-expressing cells are the largest proliferating cell population in the adult central nervous system. The function of NG2 proteoglycan or NG2-expressing…”
Get full text

Bipotential glial precursor cells of the optic nerve express the NG2 proteoglycan by Stallcup, WB, Beasley, L

“…We have studied the expression of the NG2 chondroitin sulfate proteoglycan on bipotential glial precursor cells in cultures of postnatal rat optic nerve…”
Get full text

Interaction between NG2 proteoglycan and PDGF α-receptor on O2A progenitor cells is required for optimal response to PDGF by Nishiyama, A., Lin, X.-H., Giese, N., Heldin, C.-H., Stallcup, W.B.

“…Previous studies on the NG2 chondroitin sulfate proteoglycan have shown that NG2 is expressed on A2B5‐positive O2A progenitor cells, which are known to respond…”
Get full text

The Primary Structure of NG2, a Novel Membrane-Spanning Proteoglycan by Nishiyama, Akiko, Dahlin, Kimberlee J., Prince, John T., Johnstone, Stephen R., Stallcup, William B.

“…The complete primary structure of the core protein of rat NG2, a large, chondroitin sulfate proteoglycan expressed on O2A progenitor cells, has been determined…”
Get full text

Expression of NG2 proteoglycan causes retention of type Vi collagen on the cell surface by NISHIYAMA, A, STALLCUP, W. B

“…NG2 is a membrane-associated chondroitin sulfate proteoglycan with a core protein of 300 kD. Previously it was shown immunochemically that the core protein of…”
Get full text

High-affinity Binding of Basic Fibroblast Growth Factor and Platelet-derived Growth Factor-AA to the Core Protein of the NG2 Proteoglycan by Goretzki, L, Burg, M A, Grako, K A, Stallcup, W B

“…NG2 is a transmembrane chondroitin sulfate proteoglycan that is expressed by immature progenitor cells in several developmental lineages and by some types of…”
Get full text

The Brain Chondroitin Sulfate Proteoglycan Brevican Associates with Astrocytes Ensheathing Cerebellar Glomeruli and Inhibits Neurite Outgrowth from Granule Neurons by Yamada, Hidekazu, Fredette, Barbara, Shitara, Kenya, Hagihara, Kazuki, Miura, Ryu, Ranscht, Barbara, Stallcup, William B, Yamaguchi, Yu

“…Brevican is a nervous system-specific chondroitin sulfate proteoglycan that belongs to the aggrecan family and is one of the most abundant chondroitin sulfate…”
Get full text

Interaction of the NG2 Chondroitin Sulfate Proteoglycan with Type VI Collagen by Stallcup, William B., Dahlin, Kimberlee, Healy, Patricia

“…The NG2 chondroitin sulfate proteoglycan is a membrane-associated molecule of ∼500 kD with a core glycoprotein of 300 kD. Both the complete proteoglycan and a…”
Get full text

Plasticity of developing cerebellar cells in vitro studied with antibodies against the NG2 antigen by Levine, JM, Stallcup, WB

“…The NG2 antigen, a chondroitin-sulfate proteoglycan, is a cell surface marker for a class of smooth protoplasmic astrocytes found throughout the brain and at…”
Get full text

Binding of the NG2 Proteoglycan to Type VI Collagen and Other Extracellular Matrix Molecules by Burg, M A, Tillet, E, Timpl, R, Stallcup, W B

“…Previous studies have suggested that the NG2 proteoglycan interacts with type VI collagen. We have further characterized this interaction using a solid phase…”
Get full text