Search Results - "Stalenhoef, Anton F."
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Evaluation and Treatment of Hypertriglyceridemia: An Endocrine Society Clinical Practice Guideline
Published in The journal of clinical endocrinology and metabolism (01-09-2012)“…Objective: The aim was to develop clinical practice guidelines on hypertriglyceridemia. Participants: The Task Force included a chair selected by The Endocrine…”
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2
Simvastatin with or without Ezetimibe in Familial Hypercholesterolemia
Published in The New England journal of medicine (03-04-2008)“…In a 2-year clinical trial, the addition of ezetimibe to simvastatin had no effect on the progression of atherosclerosis, as measured by carotid-artery…”
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3
Familial hypercholesterolaemia in children and adolescents: gaining decades of life by optimizing detection and treatment
Published in European heart journal (21-09-2015)“…Familial hypercholesterolaemia (FH) is a common genetic cause of premature coronary heart disease (CHD). Globally, one baby is born with FH every minute. If…”
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4
Homozygous autosomal dominant hypercholesterolaemia in the Netherlands: prevalence, genotype-phenotype relationship, and clinical outcome
Published in European heart journal (01-03-2015)“…Homozygous autosomal dominant hypercholesterolaemia (hoADH), an orphan disease caused by mutations in low-density lipoprotein receptor (LDLR), apolipoprotein B…”
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Cardiometabolic Differences in People Living with HIV Receiving Integrase Strand Transfer Inhibitors Compared to Non-nucleoside Reverse Transcriptase Inhibitors: Implications for Current ART Strategies
Published in Viruses (01-04-2024)“…In people living with HIV (PLHIV), integrase strand transfer inhibitors (INSTIs) are part of the first-line combination antiretroviral therapy (cART), while…”
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6
What is the role of non-invasive measurements of atherosclerosis in individual cardiovascular risk prediction?
Published in Clinical science (1979) (01-05-2007)“…Primary prevention of CVD (cardiovascular disease) is mainly based on the assessment of individual cardiovascular risk factors. However, often, only the most…”
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The Inflammasome and Caspase-1 Activation: A New Mechanism Underlying Increased Inflammatory Activity in Human Visceral Adipose Tissue
Published in Endocrinology (Philadelphia) (01-10-2011)“…The immune competent abdominal adipose tissue, either stored viscerally [visceral adipose tissue (VAT)] or sc [sc adipose tissue (SAT)], has been identified as…”
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Deficiency of interleukin-18 in mice leads to hyperphagia, obesity and insulin resistance
Published in Nature medicine (01-06-2006)“…Here we report the presence of hyperphagia, obesity and insulin resistance in knockout mice deficient in IL-18 or IL-18 receptor, and in mice transgenic for…”
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Association of fasting and nonfasting serum triglycerides with cardiovascular disease and the role of remnant-like lipoproteins and small dense LDL
Published in Current opinion in lipidology (01-08-2008)“…The magnitude of the contribution of serum triglycerides to cardiovascular disease risk and the mechanisms by which triglyceride-rich lipoproteins exert their…”
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10
The Metabolic Syndrome and Its Traits as Risk Factors for Subclinical Atherosclerosis
Published in The journal of clinical endocrinology and metabolism (01-08-2009)“…Context and objective: The metabolic syndrome (MetS) indicates an increased cardiovascular risk. The objective of the present study was to determine the impact…”
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Modulation of lipoprotein plasma concentrations during long-term anti-TNF therapy in patients with active rheumatoid arthritis
Published in Annals of the rheumatic diseases (01-11-2007)“…Objective:Durable blockade of tumour necrosis factor-alpha (TNF-α) in patients with rheumatoid arthritis (RA) suppresses disease activity and its progression…”
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12
Familial Combined Hyperlipidemia Is Associated With Alterations in the Cholesterol Synthesis Pathway
Published in Arteriosclerosis, thrombosis, and vascular biology (01-01-2010)“…OBJECTIVES—Familial combined hyperlipidemia (FCH) is a common familial lipid disorder characterized by increases in plasma total cholesterol, triglyceride, and…”
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13
Combining risk markers improves cardiovascular risk prediction in women
Published in Clinical science (1979) (01-01-2014)“…Cardiovascular risk stratification could be improved by adding measures of atherosclerosis to current risk scores, especially in intermediate-risk individuals…”
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14
The benefit of statins in non-cardiac vascular surgery patients
Published in Journal of vascular surgery (2009)“…There is overwhelming evidence that statins reduce morbidity and mortality in patients with coronary disease. Statins have also been shown to reduce the risk…”
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15
Simvastatin Treatment for Inflammatory Attacks of the Hyperimmunoglobulinemia D and Periodic Fever Syndrome
Published in Clinical pharmacology and therapeutics (01-05-2004)“…Hyperimmunoglobulinemia D (hyper‐IgD) and periodic fever syndrome, a hereditary autoinflammatory syndrome, is characterized by lifelong recurrent episodes of…”
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Circulating Leptin and Adiponectin Concentrations During Tumor Necrosis Factor Blockade in Patients with Active Rheumatoid Arthritis
Published in Journal of rheumatology (01-04-2009)“…Objective. Adipocytokines, including leptin and adiponectin, may play an important role in the pathogenesis of rheumatoid arthritis (RA). We investigated the…”
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17
The expression of type III hyperlipoproteinemia: involvement of lipolysis genes
Published in European journal of human genetics : EJHG (01-05-2009)“…Type III hyperlipoproteinemia (HLP) is mainly found in homozygous apolipoprotein (APO) E2 (R158C) carriers. Genetic factors contributing to the expression of…”
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18
Colesevelam added to combination therapy with a statin and ezetimibe in patients with familial hypercholesterolemia: A 12-week, multicenter, randomized, double-blind, controlled trial
Published in Clinical therapeutics (01-04-2010)“…Abstract Background: Familial hypercholesterolemia (FH) has been associated with increased cardiovascular risk when untreated or when normal LDL-C…”
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Effects of ubiquinone (coenzyme Q10) on myopathy in statin users
Published in Current opinion in lipidology (01-12-2008)“…Statins are associated with muscle complaints, including myositis. The mechanism through which statin use causes muscle toxicity is unknown. One of the…”
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Paraoxonase (PON1) and the risk for coronary heart disease and myocardial infarction in a general population of Dutch women
Published in Atherosclerosis (01-08-2008)“…Abstract There is strong evidence from both animal- and in vitro-models that paraoxonase (PON1) is involved in the onset of cardiovascular disease. In humans…”
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