Search Results - "Stalder, Anna K"

Orbit Image Analysis: An open-source whole slide image analysis tool by Stritt, Manuel, Stalder, Anna K, Vezzali, Enrico

“…We describe Orbit Image Analysis, an open-source whole slide image analysis tool. The tool consists of a generic tile-processing engine which allows the…”
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Transmission and spreading of tauopathy in transgenic mouse brain by Crowther, R. Anthony, Clavaguera, Florence, Abramowski, Dorothee, Goedert, Michel, Bolmont, Tristan, Probst, Alphonse, Tolnay, Markus, Fraser, Graham, Staufenbiel, Matthias, Stalder, Anna K, Jucker, Mathias, Beibel, Martin, Frank, Stephan

“…Hyperphosphorylated tau makes up the filamentous intracellular inclusions of several neurodegenerative diseases, including Alzheimer's disease. In the disease…”
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A fully automated image analysis method to quantify lung fibrosis in the bleomycin-induced rat model by Seger, Shanon, Stritt, Manuel, Vezzali, Enrico, Nayler, Oliver, Hess, Patrick, Groenen, Peter M A, Stalder, Anna K

“…Intratracheal administration of bleomycin induces fibrosis in the lung, which is mainly assessed by histopathological grading that is subjective. Current…”
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Vascular Damage, Thromboinflammation, Plasmablast Activation, T-Cell Dysregulation and Pathological Histiocytic Response in Pulmonary Draining Lymph Nodes of COVID-19 by Haslbauer, Jasmin D, Zinner, Carl, Stalder, Anna K, Schneeberger, Jan, Menter, Thomas, Bassetti, Stefano, Mertz, Kirsten D, Went, Philip, Matter, Matthias S, Tzankov, Alexandar

“…Although initial immunophenotypical studies on peripheral blood and bronchoalveolar lavage samples have provided a glimpse into the immunopathology of…”
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Characterisation of cardiac pathology in 23 autopsies of lethal COVID‐19 by Haslbauer, Jasmin D, Tzankov, Alexandar, Mertz, Kirsten D, Schwab, Nathalie, Nienhold, Ronny, Twerenbold, Raphael, Leibundgut, Gregor, Stalder, Anna K, Matter, Matthias, Glatz, Katharina

“…While coronavirus disease 2019 (COVID‐19) primarily affects the respiratory tract, pathophysiological changes of the cardiovascular system remain to be…”
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Dual induction of TREM2 and tolerance-related transcript, Tmem176b, in amyloid transgenic mice: implications for vaccine-based therapies for Alzheimer's disease by Melchior, Benoit, Garcia, Angie E, Hsiung, Bor-Kai, Lo, Katherine M, Doose, Jonathan M, Thrash, J Cameron, Stalder, Anna K, Staufenbiel, Matthias, Neumann, Harald, Carson, Monica J

“…Vaccine-based autoimmune (anti-amyloid) treatments are currently being examined for their therapeutic potential in Alzheimer's disease. In the present study we…”
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SARS-CoV-2 infects human pancreatic β cells and elicits β cell impairment by Wu, Chien-Ting, Lidsky, Peter V., Xiao, Yinghong, Lee, Ivan T., Cheng, Ran, Nakayama, Tsuguhisa, Jiang, Sizun, Demeter, Janos, Bevacqua, Romina J., Chang, Charles A., Whitener, Robert L., Stalder, Anna K., Zhu, Bokai, Chen, Han, Goltsev, Yury, Tzankov, Alexandar, Nayak, Jayakar V., Nolan, Garry P., Matter, Matthias S., Andino, Raul, Jackson, Peter K.

“…Emerging evidence points toward an intricate relationship between the pandemic of coronavirus disease 2019 (COVID-19) and diabetes. While preexisting diabetes…”
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Biomarker‐guided clinical development of the first‐in‐class anti‐inflammatory FPR2/ALX agonist ACT‐389949 by Stalder, Anna K., Lott, Dominik, Strasser, Daniel S., Cruz, Hans G., Krause, Andreas, Groenen, Peter M.A., Dingemanse, Jasper

“…Aims The main objectives of these two phase I studies were to investigate safety and tolerability as well as the pharmacokinetic/pharmacodynamic profile of the…”
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Eosinophilic oesophagitis: relevance of mast cell infiltration by Strasser, Daniel S, Seger, Shanon, Bussmann, Christian, Pierlot, Gabin M, Groenen, Peter M A, Stalder, Anna K, Straumann, Alex

“…Aims Eosinophilic oesophagitis (EoE) is a chronic inflammatory disease characterised clinically by symptoms of oesophageal dysfunction and histopathologically…”
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The pulmonary vasculature in lethal COVID-19 and idiopathic pulmonary fibrosis at single-cell resolution by de Rooij, Laura P M H, Becker, Lisa M, Teuwen, Laure-Anne, Boeckx, Bram, Jansen, Sander, Feys, Simon, Verleden, Stijn, Liesenborghs, Laurens, Stalder, Anna K, Libbrecht, Sasha, Van Buyten, Tina, Philips, Gino, Subramanian, Abhishek, Dumas, Sébastien J, Meta, Elda, Borri, Mila, Sokol, Liliana, Dendooven, Amélie, Truong, Anh-Co K, Gunst, Jan, Van Mol, Pierre, Haslbauer, Jasmin D, Rohlenova, Katerina, Menter, Thomas, Boudewijns, Robbert, Geldhof, Vincent, Vinckier, Stefan, Amersfoort, Jacob, Wuyts, Wim, Van Raemdonck, Dirk, Jacobs, Werner, Ceulemans, Laurens J, Weynand, Birgit, Thienpont, Bernard, Lammens, Martin, Kuehnel, Mark, Eelen, Guy, Dewerchin, Mieke, Schoonjans, Luc, Jonigk, Danny, van Dorpe, Jo, Tzankov, Alexandar, Wauters, Els, Mazzone, Massimiliano, Neyts, Johan, Wauters, Joost, Lambrechts, Diether, Carmeliet, Peter

“…Severe acute respiratory syndrome coronavirus-2 infection causes COVID-19, which in severe cases evokes life-threatening acute respiratory distress syndrome…”
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Morphologic and molecular analysis of liver injury after SARS-CoV-2 vaccination reveals distinct characteristics by Uzun, Sarp, Zinner, Carl, Beenen, Amke C., Alborelli, Ilaria, Bartoszek, Ewelina M., Yeung, Jason, Calgua, Byron, Reinscheid, Matthias, Bonsert, Peter, Stalder, Anna K., Haslbauer, Jasmine, Vosbeck, Jürg, Mazzucchelli, Luca, Hoffmann, Tobias, Terracciano, Luigi M., Hutter, Gregor, Manz, Michael, Panne, Isabelle, Böttler, Tobias, Hofmann, Maike, Bengsch, Bertram, Heim, Markus H., Bernsmeier, Christine, Jiang, Sizun, Tzankov, Alexandar, Beretta-Piccoli, Benedetta Terziroli, Matter, Matthias S.

“…Liver injury after COVID-19 vaccination is very rare and shows clinical and histomorphological similarities with autoimmune hepatitis (AIH). Little is known…”
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Transgenic expression of TNF by astrocytes increases mechanical allodynia in a mouse neuropathy model by DeLeo, Joyce A, Rutkowski, Maria D, Stalder, Anna K, Campbell, Iain L

“…It has been hypothesized that increased expression of proinflammatory cytokines mediate a variety of central nervous system disorders such as multiple…”
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A semi-automated method to assess intraepidermal nerve fibre density in human skin biopsies by Seger, Shanon, Stritt, Manuel, Doppler, Kathrin, Frank, Stephan, Panaite, Adrian, Kuntzer, Thierry, Steck, Andreas, Pagenstecher, Axel, Sommer, Claudia, Stalder, Anna K

“…Aims Evaluation of intraepidermal nerve fibres (IENFs) in skin biopsies is used in the diagnosis of small‐fibre neuropathies. The number of IENFs is assessed…”
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Von Willebrand factor and the thrombophilia of severe COVID-19: in situ evidence from autopsies by van den Berg, Jana, Haslbauer, Jasmin D., Stalder, Anna K., Romanens, Anna, Mertz, Kirsten D., Studt, Jan-Dirk, Siegemund, Martin, Buser, Andreas, Holbro, Andreas, Tzankov, Alexandar

“…COVID-19 is accompanied by a hypercoagulable state and characterized by microvascular and macrovascular thrombotic complications. In plasma samples from…”
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Anti-myelin-associated glycoprotein neuropathy by Steck, Andreas J, Stalder, Anna K, Renaud, Susanne

“…The anti-myelin-associated glycoprotein (MAG) neuropathy is an antibody-mediated demyelinating neuropathy. The clinical picture is characterized by a distal…”
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Invasion of Hematopoietic Cells into the Brain of Amyloid Precursor Protein Transgenic Mice by Stalder, Anna K, Ermini, Florian, Bondolfi, Luca, Krenger, Werner, Burbach, Guido J, Deller, Thomas, Coomaraswamy, Janaky, Staufenbiel, Matthias, Landmann, Regine, Jucker, Mathias

“…The significance of the peripheral immune system in Alzheimer's disease pathogenesis remains controversial. To study the CNS invasion of hematopoietic cells in…”
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Determinants of SARS-CoV-2 entry and replication in airway mucosal tissue and susceptibility in smokers by Nakayama, Tsuguhisa, Lee, Ivan T., Jiang, Sizun, Matter, Matthias S., Yan, Carol H., Overdevest, Jonathan B., Wu, Chien-Ting, Goltsev, Yury, Shih, Liang-Chun, Liao, Chun-Kang, Zhu, Bokai, Bai, Yunhao, Lidsky, Peter, Xiao, Yinghong, Zarabanda, David, Yang, Angela, Easwaran, Meena, Schürch, Christian M., Chu, Pauline, Chen, Han, Stalder, Anna K., McIlwain, David R., Borchard, Nicole A., Gall, Phillip A., Dholakia, Sachi S., Le, Wei, Xu, Le, Tai, Chih-Jaan, Yeh, Te-Huei, Erickson-Direnzo, Elizabeth, Duran, Jason M., Mertz, Kirsten D., Hwang, Peter H., Haslbauer, Jasmin D., Jackson, Peter K., Menter, Thomas, Andino, Raul, Canoll, Peter D., DeConde, Adam S., Patel, Zara M., Tzankov, Alexandar, Nolan, Garry P., Nayak, Jayakar V.

“…Understanding viral tropism is an essential step toward reducing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission, decreasing…”
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Preclinical to clinical translation of cenerimod, a novel S1P 1 receptor modulator, in systemic lupus erythematosus by Strasser, Daniel S, Froidevaux, Sylvie, Sippel, Virginie, Gerossier, Estelle, Grieder, Ursula, Pierlot, Gabin M, Kieninger-Graefitsch, Andrea, Vezzali, Enrico, Stalder, Anna K, Renault, Bérengère, Ryge, Jesper, Hart, Aaron, Mentzel, Ulrich, Groenen, Peter M A, Keller, Marcel P, Trendelenburg, Marten, Martinic, Marianne M, Murphy, Mark J

“…Objectives: SLE is an autoimmune disease characterised by aberrant lymphocyte activation and autoantibody production. This study provides an in-depth…”
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Immunoglobulin M Deposition in Cutaneous Nerves of Anti-Myelin-Associated Glycoprotein Polyneuropathy Patients Correlates With Axonal Degeneration by Stalder, Anna K, Erne, Beat, Reimann, Regina, Renaud, Susanne, Fuhr, Peter, Thomann, Sandra, Arnold, Andreas, Probst, Alphonse, Schaeren-Wiemers, Nicole, Steck, Andreas J

“…Anti-myelin-associated glycoprotein (MAG) neuropathy is an antibody-mediated polyneuropathy. We correlated clinical features, immunoglobulin (Ig) M blood…”
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mTOR is expressed in polymyositis but not in sporadic inclusion body myositis by Panaite, Petrica-Adrian, Stalder, Anna K, Ipsen, Sabine, Kuntzer, Thierry, Steck, Andreas J

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