Search Results - "Stakaitis, Rytis"
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Identification and comparison of m6A modifications in glioblastoma non-coding RNAs with MeRIP-seq and Nanopore dRNA-seq
Published in Epigenetics (31-12-2023)“…The most prominent RNA modification - N6-methyladenosine (m6A) - affects gene regulation and cancer progression. The extent and effect of m6A on long…”
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Journal Article -
2
Transcriptome-wide analysis of glioma stem cell specific m6A modifications in long-non-coding RNAs
Published in Scientific reports (31-03-2022)“…The interest in chemical RNA modifications is rapidly growing in the field of molecular biology. Dynamic and reversible alterations of N6-methyladenosine (m6A)…”
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3
The Role of CASC2 and miR-21 Interplay in Glioma Malignancy and Patient Outcome
Published in International journal of molecular sciences (27-10-2020)“…Recently long non-coding RNAs (lncRNAs) were highlighted for their regulatory role in tumor biology. The novel human lncRNA cancer susceptibility candidate 2 (…”
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4
Unique Interplay Between Molecular miR-181b/d Biomarkers and Health Related Quality of Life Score in the Predictive Glioma Models
Published in International journal of molecular sciences (09-10-2020)“…In the last decade, an increasing amount of research has been conducted analyzing microRNA expression changes in glioma tissue and its expressed exosomes, but…”
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5
Inherited defects of piRNA biogenesis cause transposon de-repression, impaired spermatogenesis, and human male infertility
Published in Nature communications (09-08-2024)“…piRNAs are crucial for transposon silencing, germ cell maturation, and fertility in male mice. Here, we report on the genetic landscape of piRNA dysfunction in…”
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6
Plasma-Derived miRNA-222 as a Candidate Marker for Papillary Thyroid Cancer
Published in International journal of molecular sciences (03-09-2020)“…We analyzed five miRNA molecules (miR-221; miR-222; miR-146b; miR-21; miR-181b) in the plasma of patients with papillary thyroid cancer (PTC), nodular goiter…”
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Circulating levels and the bioactivity of miR-30b increase during pubertal progression in boys
Published in Frontiers in endocrinology (Lausanne) (19-01-2023)“…Puberty marks the transition from childhood to adulthood and is initiated by activation of a pulsatile GnRH secretion from the hypothalamus. MKRN3 functions as…”
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Antisense lncRNA CHROMR is linked to glioma patient survival
Published in Frontiers in molecular biosciences (06-03-2023)“…Natural non-coding antisense transcripts (ncNATs) are long non-coding RNAs (lncRNA) transcribed from the opposite strand of a separate protein coding or…”
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Papillary Thyroid Carcinoma Tissue miR-146b, -21, -221, -222, -181b Expression in Relation with Clinicopathological Features
Published in Diagnostics (Basel) (02-03-2021)“…We analyzed miR-146b, miR-21, miR-221, miR-21, and miR-181b in formalin fixed paraffin-embedded papillary thyroid carcinoma (PTC) tissue samples of 312…”
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10
Mirna Studies of Tumor Tissue and Blood Extracellular Vesicles for Diagnosis and Prognosis of Gliomas
Published 01-01-2023“…Gliomas are the most prevalent type of primary malignant brain tumors and are central nervous system (CNS) tumors that develop in the brain from glial cells…”
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Dissertation -
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Variant PNLDC1, Defective piRNA Processing, and Azoospermia
Published in The New England journal of medicine (19-08-2021)“…A particular class of small noncoding RNAs are transcribed from DNA and then processed by enzymes to generate short oligonucleotides that then control gene…”
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12
Diverse monogenic subforms of human spermatogenic failure
Published in Nature communications (26-12-2022)“…Non-obstructive azoospermia (NOA) is the most severe form of male infertility and typically incurable. Defining the genetic basis of NOA has proven…”
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13
Association of miR-34a Expression with Quality of Life of Glioblastoma Patients: A Prospective Study
Published in Cancers (04-03-2019)“…MiR-34a acts as tumor-suppressor by targeting many oncogenes related to proliferation, apoptosis, and invasion of gliomas. We studied the relationships between…”
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14
The piRNA-pathway factor FKBP6 is essential for spermatogenesis but dispensable for control of meiotic LINE-1 expression in humans
Published in American journal of human genetics (06-10-2022)“…Infertility affects around 7% of the male population and can be due to severe spermatogenic failure (SPGF), resulting in no or very few sperm in the ejaculate…”
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15
High CHI3L1 expression is associated with glioma patient survival
Published in Diagnostic pathology (27-04-2016)“…Survival of glioma patients with the same tumor histology and grade can vary significantly, and some low-grade gliomas transform to a more malignant phenotype…”
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Small RNAs in Seminal Plasma as Novel Biomarkers for Germ Cell Tumors
Published in Cancers (13-05-2021)“…Circulating miRNAs secreted by testicular germ cell tumors (TGCT) show great potential as novel non-invasive biomarkers for diagnosis of TGCT. Seminal plasma…”
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Journal Article