Search Results - "Stairs, Dustin J"

Deletion of glutamate delta-1 receptor in mouse leads to enhanced working memory and deficit in fear conditioning by Yadav, Roopali, Hillman, Brandon G, Gupta, Subhash C, Suryavanshi, Pratyush, Bhatt, Jay M, Pavuluri, Ratnamala, Stairs, Dustin J, Dravid, Shashank M

“…Glutamate delta-1 (GluD1) receptors are expressed throughout the forebrain during development with high levels in the hippocampus during adulthood. We have…”
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Deletion of glutamate delta-1 receptor in mouse leads to aberrant emotional and social behaviors by Yadav, Roopali, Gupta, Subhash C, Hillman, Brandon G, Bhatt, Jay M, Stairs, Dustin J, Dravid, Shashank M

“…The delta family of ionotropic glutamate receptors consists of glutamate δ1 (GluD1) and glutamate δ2 (GluD2) receptors. While the role of GluD2 in the…”
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The NMDA receptor GluN2C subunit controls cortical excitatory-inhibitory balance, neuronal oscillations and cognitive function by Gupta, Subhash C., Ravikrishnan, Aparna, Liu, Jinxu, Mao, Zhihao, Pavuluri, Ratnamala, Hillman, Brandon G., Gandhi, Pauravi J., Stairs, Dustin J., Li, Ming, Ugale, Rajesh R., Monaghan, Daniel T., Dravid, Shashank M.

“…Despite strong evidence for NMDA receptor (NMDAR) hypofunction as an underlying factor for cognitive disorders, the precise roles of various NMDAR subtypes…”
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Essential role of GluD1 in dendritic spine development and GluN2B to GluN2A NMDAR subunit switch in the cortex and hippocampus reveals ability of GluN2B inhibition in correcting hyperconnectivity by Gupta, Subhash C., Yadav, Roopali, Pavuluri, Ratnamala, Morley, Barbara J., Stairs, Dustin J., Dravid, Shashank M.

“…The glutamate delta-1 (GluD1) receptor is highly expressed in the forebrain. We have previously shown that loss of GluD1 leads to social and cognitive deficits…”
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Impulsive choice and environmental enrichment: Effects of d-amphetamine and methylphenidate by Perry, Jennifer L., Stairs, Dustin J., Bardo, Michael T.

“…Individual differences in impulsive choice and rearing in differential environments are factors that predict vulnerability to drug abuse. The present study…”
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Behavioral analysis of NR2C knockout mouse reveals deficit in acquisition of conditioned fear and working memory by Hillman, Brandon G., Gupta, Subhash C., Stairs, Dustin J., Buonanno, Andres, Dravid, Shashank M.

“…► NR2C knockout mice exhibit deficit in cued and contextual fear conditioning. ► Conditioning-induced thalamo-amygdala synaptic strengthening is absent in NR2C…”
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Neurobehavioral effects of environmental enrichment and drug abuse vulnerability: An updated review by Malone, Samantha G., Shaykin, Jakob D., Stairs, Dustin J., Bardo, Michael T.

“…Environmental enrichment consisting of social peers and novel objects is known to alter neurobiological functioning and have an influence on the behavioral…”
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Neurobehavioral effects of environmental enrichment and drug abuse vulnerability by Stairs, Dustin J., Bardo, Michael T.

“…Environmental enrichment during development produces a host of neurobehavioral effects in preclinical models. Early work demonstrated that enrichment enhances…”
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Advancing the Translation Between Clinical and Preclinical Models of Individual Differences in Vulnerability in Substance Use Disorders by Stairs, Dustin J, Cyders, Melissa A

“…Whereas the majority of individuals in society experiment with drugs and alcohol, only a small subset develops problems or disorders related to such use…”
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Nicotine drug discrimination and nicotinic acetylcholine receptors in differentially reared rats by Bockman, Charles S., Zeng, Wanyun, Hall, Jamie, Mittelstet, Beth, Schwarzkopf, Liz, Stairs, Dustin J.

“…Rationale Individuals vary in sensitivity to the behavioral effects of nicotine, resulting in differences in vulnerability to nicotine addiction. The role of…”
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Environmental enrichment increases cue-dependent freezing and behavioral despair but decreases anxiety-like behavior in rats by Stairs, Dustin J., Chacho, Nicole M., Wunsch, Connor, Pipitone, Lauren, Dravid, Shashank M.

“…While post-traumatic stress disorder (PTSD) can develop after exposure to severe traumatic events, data have shown that individuals with high sensation-seeking…”
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Differential effect of NMDA receptor GluN2C and GluN2D subunit ablation on behavior and channel blocker-induced schizophrenia phenotypes by Shelkar, Gajanan P., Pavuluri, Ratnamala, Gandhi, Pauravi J., Ravikrishnan, Aparna, Gawande, Dinesh Y., Liu, Jinxu, Stairs, Dustin J., Ugale, Rajesh R., Dravid, Shashank M.

“…The GluN2C- and GluN2D-containing NMDA receptors are distinct from GluN2A- and GluN2B-containing receptors in many aspects including lower sensitivity to Mg 2+…”
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Enrichment-induced differences in methamphetamine drug discrimination in male rats by Chacho, Nicole M., Adams, Emily, Stairs, Dustin J.

“…Rats raised in an enriched environment show a decrease in sensitivity to the subjective effects of the psychostimulant d-amphetamine. The purpose of the…”
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Environmental-induced differences in corticosterone and glucocorticoid receptor blockade of amphetamine self-administration in rats by Stairs, Dustin J., Prendergast, Mark A., Bardo, Michael T.

“…Rationale Rats raised in isolation self-administer more amphetamine than rats raised in enrichment. Objective This study examined whether differential rearing…”
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Effects of environmental enrichment on nicotine-induced sensitization and cross-sensitization to d -amphetamine in rats by Adams, Emily, Klug, Jenna, Quast, Michaela, Stairs, Dustin J

“…Abstract Introduction Research indicates that adolescent nicotine exposure may predispose individuals to use other psychostimulants later in adulthood,…”
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Varenicline and GZ-793A differentially decrease methamphetamine self-administration under a multiple schedule of reinforcement in rats by Kangiser, Megan M, Dwoskin, Linda P, Zheng, Guangrong, Crooks, Peter A, Stairs, Dustin J

“…Methamphetamine is a potent psychostimulant with high abuse rates. Currently, there is no Food and Drug Administration-approved pharmacotherapy for…”
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Effects of Environmental Enrichment on d-Amphetamine Self-Administration Following Nicotine Exposure by Stairs, Dustin J, Ewin, Sarah E, Kangiser, Megan M, Pfaff, Markus N

“…Adolescent nicotine exposure has been shown to lead to further psychostimulant use in adulthood. Previous preclinical research in rats has shown that…”
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Effects of environmental enrichment on amphetamine self-administration under a fixed-ratio and progressive ratio schedule following nicotine exposure by Stairs, Dustin J, Ewin, Sarah, Kangiser, Megan, Salvatore, Chris, Pfaff, Markus

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Effect of D-cycloserine in conjunction with fear extinction training on extracellular signal-regulated kinase activation in the medial prefrontal cortex and amygdala in rat by Gupta, Subhash C., Hillman, Brandon G., Prakash, Anand, Ugale, Rajesh R., Stairs, Dustin J., Dravid, Shashank M.

“…D‐cycloserine (DCS) is currently under clinical trials for a number of neuropsychiatric conditions and has been found to augment fear extinction in rodents and…”
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Effects of varenicline and GZ-793A on methamphetamine and food self-administration under a multiple schedule of reinforcement in rats by Stairs, Dustin J, Kangiser, Megan, Pfaff, Markus N, Ewin, Sarah, Dwoskin, Linda P

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