Search Results - "Stair, Neil"

Caspase-8 is the molecular switch for apoptosis, necroptosis and pyroptosis by Fritsch, Melanie, Günther, Saskia D., Schwarzer, Robin, Albert, Marie-Christine, Schorn, Fabian, Werthenbach, J. Paul, Schiffmann, Lars M., Stair, Neil, Stocks, Hannah, Seeger, Jens M., Lamkanfi, Mohamed, Krönke, Martin, Pasparakis, Manolis, Kashkar, Hamid

“…Caspase-8 is the initiator caspase of extrinsic apoptosis 1 , 2 and inhibits necroptosis mediated by RIPK3 and MLKL. Accordingly, caspase-8 deficiency in mice…”
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Butyrate and propionate are microbial danger signals that activate the NLRP3 inflammasome in human macrophages upon TLR stimulation by Wang, Wei, Dernst, Alesja, Martin, Bianca, Lorenzi, Lucia, Cadefau-Fabregat, Maria, Phulphagar, Kshiti, Wagener, Antonia, Budden, Christina, Stair, Neil, Wagner, Theresa, Färber, Harald, Jaensch, Andreas, Stahl, Rainer, Duthie, Fraser, Schmidt, Susanne V., Coll, Rebecca C., Meissner, Felix, Cuartero, Sergi, Latz, Eicke, Mangan, Matthew S.J.

“…Short-chain fatty acids (SCFAs) are immunomodulatory compounds produced by the microbiome through dietary fiber fermentation. Although generally considered…”
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Tumour-infiltrating neutrophils counteract anti-VEGF therapy in metastatic colorectal cancer by Schiffmann, Lars Mortimer, Fritsch, Melanie, Gebauer, Florian, Günther, Saskia Diana, Stair, Neil Richard, Seeger, Jens Michael, Thangarajah, Fabinshy, Dieplinger, Georg, Bludau, Marc, Alakus, Hakan, Göbel, Heike, Quaas, Alexander, Zander, Thomas, Hilberg, Frank, Bruns, Christiane Josephine, Kashkar, Hamid, Coutelle, Oliver

“…Background Immune infiltration is implicated in the development of acquired resistance to anti-angiogenic cancer therapy. We therefore investigated the…”
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