Search Results - "Staib, Frank"

Sniffer dogs can identify lung cancer patients from breath and urine samples by Feil, Charlotte, Staib, Frank, Berger, Martin R, Stein, Thorsten, Schmidtmann, Irene, Forster, Andreas, Schimanski, Carl C

“…Lung cancer is the most common oncological cause of death in the Western world. Early diagnosis is critical for successful treatment. However, no effective…”
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Genetics of hepatocellular carcinoma by Teufel, Andreas, Staib, Frank, Kanzler, Stephan, Weinmann, Arndt, Schulze-Bergkamen, Henning, Galle, Peter-R

“…The completely assembled human genome has made it possible for modern medicine to step into an era rich in genetic information and high-throughput genomic…”
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Loss of LLGL1 Expression Correlates with Diffuse Gastric Cancer and Distant Peritoneal Metastases by Schimanski, Carl C., Berger, Martin R., Maderer, Annett, Biesterfeld, Stefan, Lang, Hauke, Moehler, Markus, Gockel, Ines, Staib, Frank, Desuki, Alexander, Galle, Peter R.

“…Background. Loss of LLGL1 has been associated with loss of cellular adhesion and dissemination of cells from colorectal cancer and malignant melanoma…”
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Genetic signatures shared in embryonic liver development and liver cancer define prognostically relevant subgroups in HCC by Becker, Diana, Sfakianakis, Ioannis, Krupp, Markus, Staib, Frank, Gerhold-Ay, Aslihan, Victor, Anja, Binder, Harald, Blettner, Maria, Maass, Thorsten, Thorgeirsson, Snorri, Galle, Peter R, Teufel, Andreas

“…Multiple activations of individual genes during embryonic liver and HCC development have repeatedly prompted speculations about conserved embryonic signatures…”
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Different Efficiency of Heat Shock Proteins (HSP) to Activate Human Monocytes and Dendritic Cells: Superiority of HSP60 by Bethke, Karen, Staib, Frank, Distler, Martin, Schmitt, Ute, Jonuleit, Helmut, Enk, Alexander H, Galle, Peter R, Heike, Michael

“…One essential immunoregulatory function of heat shock protein (HSP) is activation of the innate immune system. We investigated the activation of human…”
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The p53 tumor suppressor network is a key responder to microenvironmental components of chronic inflammatory stress by STAIB, Frank, ROBLES, Ana I, GALLE, Peter R, HARRIS, Curtis C, VARTICOVSKI, Lyuba, WANG, Xin W, ZEEBERG, Barry R, SIROTIN, Michail, ZHURKIN, Victor B, HOFSETH, Lorne J, HUSSAIN, S. Perwez, WEINSTEIN, John N

“…Activation of the p53 network plays a central role in the inflammatory stress response associated with ulcerative colitis and may modulate cancer risk in…”
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ΔNp73β is oncogenic in hepatocellular carcinoma by blocking apoptosis signaling via death receptors and mitochondria by Schuster, André, Schilling, Tobias, De Laurenzi, Vincenzo, Koch, Andreas F., Seitz, Sarah, Staib, Frank, Teufel, Andreas, Thorgeirsson, Snorri S., Galle, Peter, Melino, Gerry, Stremmel, Wolfgang, Krammer, Peter H., Müller, Martina

“…Background & Aims: p73 belongs to the p53 family of transcription factors known to regulate cell cycle and apoptosis. The Trp73 gene has two promoters that…”
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The functional cancer map: a systems-level synopsis of genetic deregulation in cancer by Krupp, Markus, Maass, Thorsten, Marquardt, Jens U, Staib, Frank, Bauer, Tobias, König, Rainer, Biesterfeld, Stefan, Galle, Peter R, Tresch, Achim, Teufel, Andreas

“…Cancer cells are characterized by massive dysegulation of physiological cell functions with considerable disruption of transcriptional regulation. Genome-wide…”
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Microarray-Based Gene Expression Analysis of Hepatocellular Carcinoma by Maass, Thorsten, Sfakianakis, Ioannis, Staib, Frank, Krupp, Markus, Galle, Peter R, Teufel, Andreas

“…Microarray studies have successfully shed light on various aspects of the molecular mechanisms behind the development of hepatocellular carcinoma (HCC), such…”
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Library of molecular associations: curating the complex molecular basis of liver diseases by Buchkremer, Stefan, Hendel, Jasmin, Krupp, Markus, Weinmann, Arndt, Schlamp, Kai, Maass, Thorsten, Staib, Frank, Galle, Peter R, Teufel, Andreas

“…Systems biology approaches offer novel insights into the development of chronic liver diseases. Current genomic databases supporting systems biology analyses…”
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Translating bioinformatics in oncology: guilt-by-profiling analysis and identification of KIF18B and CDCA3 as novel driver genes in carcinogenesis by Itzel, Timo, Scholz, Peter, Maass, Thorsten, Krupp, Markus, Marquardt, Jens U, Strand, Susanne, Becker, Diana, Staib, Frank, Binder, Harald, Roessler, Stephanie, Wang, Xin Wei, Thorgeirsson, Snorri, Müller, Martina, Galle, Peter R, Teufel, Andreas

“…Co-regulated genes are not identified in traditional microarray analyses, but may theoretically be closely functionally linked [guilt-by-association (GBA),…”
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Chemotherapy‐induced apoptosis in hepatocellular carcinoma involves the p53 family and is mediated via the extrinsic and the intrinsic pathway by Seitz, Sarah J., Schleithoff, Elisa Schulze, Koch, Andreas, Schuster, André, Teufel, Andreas, Staib, Frank, Stremmel, Wolfgang, Melino, Gerry, Krammer, Peter H., Schilling, Tobias, Müller, Martina

“…We investigated the downstream mechanisms by which chemotherapeutic drugs elicit apoptosis in hepatocellular carcinoma (HCC). Genomic signatures of HCC cell…”
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Neutrophilic disease of the skin and intestines after ipilimumab treatment for malignant melanoma — simultaneous occurrence of pyoderma gangrenosum and colitis by Rudolph, Berenice M., Staib, Frank, Von Stebut, Esther, Hainz, Michael, Grabbe, Stephan, Loquai, Carmen

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Snapshot liver transcriptome in hepatocellular carcinoma by Teufel, Andreas, Marquardt, Jens U, Staib, Frank, Galle, Peter R

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Adaptive immunity suppresses formation and progression of diethylnitrosamine-induced liver cancer by Schneider, Carlo, Teufel, Andreas, Yevsa, Tetyana, Staib, Frank, Hohmeyer, Anja, Walenda, Gudrun, Zimmermann, Henning W, Vucur, Mihael, Huss, Sebastian, Gassler, Nikolaus, Wasmuth, Hermann E, Lira, Sergio A, Zender, Lars, Luedde, Tom, Trautwein, Christian, Tacke, Frank

“…Hepatocellular carcinoma (HCC) is a typical inflammation-associated cancer, but may also provoke antitumour immune responses whose significance and underlying…”
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Dermatux: Phase IV trial of C-FOLFIRI in 1 st -line metastatic colorectal cancer receiving a pre-defined skin care by Schimanski, Carl Christoph, Staib, Frank, Goehler, Thomas, Hebart, Holger Frithjof, Neise, Michael, Rudi, Jochen, Geer, Thomas, Ehscheidt, Peter, Flohr, Thomas, Schmittel, Alexander H., Galle, Peter R., Moehler, Markus H.

“…Abstract only…”
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Dermatux: phase IV trial of Cetuximab plus FOLFIRI in first-line metastatic colorectal cancer receiving a pre-defined skin care by Schimanski, Carl Christoph, Staib, Frank, Göhler, Thomas, Hebart, Holger, Heike, Michael, Neise, Michael, Rudi, Jochen, Geer, Thomas, Dingeldein, Gerrit, Lang, Claudia, Ehscheidt, Peter, Flohr, Thomas, Josten, Klaus Maria, Karthaus, Meinolf, Schmittel, Alexander, Wierecky, Jan, Boller, Emil, Indorf, Martin, Wörns, Marcus-Alexander, Galle, Peter R., Moehler, Markus

“…Purpose Cetuximab-induced skin rash Gd3+ occurs in ≥16% patients (pts) (Heinemann et al., Lancet Oncol 15(10):1065–1075, 2014 ; Van Cutsem et al. J Clin Oncol…”
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CellMinerHCC: a microarray-based expression database for hepatocellular carcinoma cell lines by Staib, Frank, Krupp, Markus, Maass, Thorsten, Itzel, Timo, Weinmann, Arndt, Lee, Ju-Seog, Schmidt, Bertil, Müller, Martina, Thorgeirsson, Snorri S., Galle, Peter R., Teufel, Andreas

“…Background & Aims Therapeutic options for hepatocellular carcinoma (HCC) still remain limited. Development of gene targeted therapies is a promising option. A…”
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TP53 and liver carcinogenesis by Staib, Frank, Perwez Hussain, S., Hofseth, Lorne J., Wang, Xin W., Harris, Curtis C.

“…Primary hepatocellular carcinoma (HCC) is one of the most common malignancies and has the fourth highest mortality rate worldwide. The major risk factors,…”
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CellMiner HCC : a microarray‐based expression database for hepatocellular carcinoma cell lines by Staib, Frank, Krupp, Markus, Maass, Thorsten, Itzel, Timo, Weinmann, Arndt, Lee, Ju‐Seog, Schmidt, Bertil, Müller, Martina, Thorgeirsson, Snorri S., Galle, Peter R., Teufel, Andreas

“…Abstract Background & Aims Therapeutic options for hepatocellular carcinoma ( HCC ) still remain limited. Development of gene targeted therapies is a promising…”
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