Search Results - "Staib, A"
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1
Whole blood coagulation and platelet activation in the athlete: a comparison of marathon, triathlon and long distance cycling
Published in European journal of medical research (26-02-2010)“…Serious thrombembolic events occur in otherwise healthy marathon athletes during competition. We tested the hypothesis that during heavy endurance sports…”
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2
A comprehensive ovine model of blood transfusion
Published in Vox sanguinis (01-02-2014)“…Background The growing awareness of transfusion‐associated morbidity and mortality necessitates investigations into the underlying mechanisms. Small animals…”
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3
Effects of grapefruit juice and smoking on verapamil concentrations in steady state
Published in European journal of clinical pharmacology (01-04-2002)“…Human gut wall cytochrome P(450) (CYP)3A4 is inhibited by grapefruit juice (G), whereas smoking increases CYP1A2 activity. Both enzymes contribute to verapamil…”
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4
Stored blood transfusion induces transient pulmonary arterial hypertension without impairing coagulation in an ovine model of nontraumatic haemorrhage
Published in Vox sanguinis (01-08-2013)“…Background and Objectives Transfusion of blood products in particular older products is associated with patient morbidity. Previously, we demonstrated a higher…”
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5
Inhibitory effect of grapefruit juice and its bitter principal, naringenin, on CYP1A2 dependent metabolism of caffeine in man
Published in British journal of clinical pharmacology (01-04-1993)“…1. The effects of grapefruit juice and naringenin on the activity of the human cytochrome P450 isoform CYP1A2 were evaluated using caffeine as a probe…”
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6
Potential of mid-infrared spectroscopy to aid the triage of patients with acute chest pain
Published in Analyst (London) (01-01-2009)“…A total of 1,429 serum samples from 389 consecutive patients with acute chest pain were analyzed with the goal to aid the rapid diagnosis of acute myocardial…”
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7
Inhibitory potency of quinolone antibacterial agents against cytochrome P450IA2 activity in vivo and in vitro
Published in Antimicrobial Agents and Chemotherapy (01-05-1992)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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8
Biotransformation of caffeine and theophylline in mammalian cell lines genetically engineered for expression of single cytochrome P450 isoforms
Published in Biochemical pharmacology (22-01-1992)“…Primary steps in the metabolism of caffeine and theophylline are cleavage of methyl groups and/or hydroxylation at position 8, mediated by cytochromes P450…”
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9
Disease pattern recognition testing for rheumatoid arthritis using infrared spectra of human serum
Published in Clinica chimica acta (01-06-2001)“…Background: In view of the importance of the diagnosis of rheumatoid arthritis, a novel diagnostic method based on spectroscopic pattern recognition in…”
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10
Cysteine proteinase cathepsin H in tumours and sera of lung cancer patients: relation to prognosis and cigarette smoking
Published in British journal of cancer (01-02-2000)“…In order to evaluate the role of cysteine peptidase cathepsin H (Cath H) in human lung cancer its protein levels were determined in 148 pairs of lung tumour…”
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11
Grapefruit juice increases oral nimodipine bioavailability
Published in International journal of clinical pharmacology and therapeutics (01-03-1998)“…The bioavailability of dihydropyridine calcium channel blockers following oral administration was shown to be increased by concomitant intake of grapefruit…”
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12
Variation of CYP1A2-dependent caffeine metabolism during menstrual cycle in healthy women
Published in International journal of clinical pharmacology and therapeutics (01-05-2000)“…The activity of the human cytochrome P450 CYP1A2 is decreased by female sex hormones during pregnancy or treatment with oral contraceptives. However, the…”
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13
Vibrational spectroscopy and molecular dynamics of solvated methanol tetramer and pentamer
Published in Chemical physics (15-09-1998)“…A mixed quantum-classical molecular dynamics study of methanol tetramer and pentamer dissolved in CCl 4 is presented. The underlying model is composed of…”
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14
Absence of Effect of Rufloxacin on Theophylline Pharmacokinetics in Steady State
Published in Antimicrobial Agents and Chemotherapy (01-09-1998)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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15
Lacking effect of grapefruit juice on theophylline pharmacokinetics
Published in International journal of clinical pharmacology and therapeutics (01-06-1995)“…Grapefruit juice inhibits the biotransformation of several drugs, including caffeine (23% clearance reduction), which is metabolized by the cytochrome P450…”
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16
L-Methadone and D,L-methadone in methadone maintenance treatment: a comparison of therapeutic effectiveness and plasma concentrations
Published in European addiction research (01-09-1998)“…The clinical effectiveness of l-methadone maintenance treatment (LMMT) carried out using d,l-methadone or l-methadone have been compared with ambulatory…”
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17
Ciprofloxacin absorption in different regions of the human gastrointestinal tract. Investigations with the hf‐capsule
Published in British journal of clinical pharmacology (01-07-1990)“…1. The absorption of ciprofloxacin from different regions of the human gastrointestinal tract was investigated in four healthy males using a remote‐controlled…”
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18
Absorption differences of ciprofloxacin along the human gastrointestinal tract determined using a remote-control drug delivery device (HF-capsule)
Published in The American journal of medicine (30-11-1989)“…The single-dose absorption kinetics of ciprofloxacin in different regions of the human gastrointestinal tract were investigated using a remote-control drug…”
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19
Series on "lifestyle drugs"
Published in International journal of clinical pharmacology and therapeutics (01-06-2001)Get more information
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20
Quinolone inhibition of cytochrome P-450-dependent caffeine metabolism in human liver microsomes
Published in Drug metabolism and disposition (01-11-1990)“…Inhibitory effects of the quinolone antibiotics ofloxacin, lomefloxacin, pipemidic acid, ciprofloxacin, and enoxacin on caffeine metabolism were examined in…”
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