Search Results - "Stahlberg, Anders"

Counting unique molecular identifiers in sequencing using a multi-type branching process with immigration by Sagitov, Serik, Ståhlberg, Anders

“…Detection of extremely rare variant alleles, such as tumor DNA, within a complex mixture of DNA molecules is experimentally challenging due to sequencing…”
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Modern methods of molecular diagnostics by Kubista, Mikael, Andersson, Daniel, Ståhlberg, Anders

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Digital Quantification of Chemical Oligonucleotide Synthesis Errors by Filges, Stefan, Mouhanna, Pia, Ståhlberg, Anders

“…Abstract Background Chemically synthesized oligonucleotides are vital to most nucleic acids-based technologies and several applications are sensitive to…”
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CRISPR-Cas target recognition for sensing viral and cancer biomarkers by Rahimi, Shadi, Balusamy, Sri Renukadevi, Perumalsamy, Haribalan, Ståhlberg, Anders, Mijakovic, Ivan

“…Nucleic acid-based diagnostics is a promising venue for detection of pathogens causing infectious diseases and mutations related to cancer. However, this type…”
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Liquid biopsy analysis in cancer diagnostics by Andersson, Daniel, Kubista, Mikael, Ståhlberg, Anders

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UMIErrorCorrect and UMIAnalyzer: Software for Consensus Read Generation, Error Correction, and Visualization Using Unique Molecular Identifiers by Österlund, Tobias, Filges, Stefan, Johansson, Gustav, Ståhlberg, Anders

“…Targeted sequencing using unique molecular identifiers (UMIs) enables detection of rare variant alleles in challenging applications, such as cell-free DNA…”
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Principles of digital sequencing using unique molecular identifiers by Andersson, Daniel, Kebede, Firaol Tamiru, Escobar, Mandy, Österlund, Tobias, Ståhlberg, Anders

“…Massively parallel sequencing technologies have long been used in both basic research and clinical routine. The recent introduction of digital sequencing has…”
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The PEMDAC phase 2 study of pembrolizumab and entinostat in patients with metastatic uveal melanoma by Ny, Lars, Jespersen, Henrik, Karlsson, Joakim, Alsén, Samuel, Filges, Stefan, All-Eriksson, Charlotta, Andersson, Bengt, Carneiro, Ana, Helgadottir, Hildur, Levin, Max, Ljuslinder, Ingrid, Olofsson Bagge, Roger, Sah, Vasu R., Stierner, Ulrika, Ståhlberg, Anders, Ullenhag, Gustav, Nilsson, Lisa M., Nilsson, Jonas A.

“…Preclinical studies have suggested that epigenetic therapy could enhance immunogenicity of cancer cells. We report the results of the PEMDAC phase 2 clinical…”
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Circulating cell-free tumor DNA analysis in pediatric cancers by Andersson, Daniel, Fagman, Henrik, Dalin, Martin G., Ståhlberg, Anders

“…Analysis of circulating cell-free tumor DNA (ctDNA) has shown promising results within several clinical applications, including cancer detection, mutation…”
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Human oocyte maturation in vitro is improved by co-culture with cumulus cells from mature oocytes by Virant-Klun, Irma, Bauer, Chris, Ståhlberg, Anders, Kubista, Mikael, Skutella, Thomas

“…The conventional method of human oocyte maturation in vitro in the presence of gonadotrophins continues to be a relatively low-success procedure in the…”
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Ultrasensitive circulating tumor DNA analysis enables precision medicine: experimental workflow considerations by Andersson, Daniel, Kristiansson, Helena, Kubista, Mikael, Ståhlberg, Anders

“…Circulating tumor DNA (ctDNA) has become a relevant biomarker in cancer management, allowing tumor assessment through analysis of minimally invasive liquid…”
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Impact of Polymerase Fidelity on Background Error Rates in Next-Generation Sequencing with Unique Molecular Identifiers/Barcodes by Filges, Stefan, Yamada, Emiko, Ståhlberg, Anders, Godfrey, Tony E.

“…Liquid biopsy and detection of tumor-associated mutations in cell-free circulating DNA often requires the ability to identify single nucleotide variants at…”
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Monitoring Circulating Tumor DNA During Surgical Treatment in Patients with Gastrointestinal Stromal Tumors by Johansson, Gustav, Berndsen, Marta, Lindskog, Stefan, Österlund, Tobias, Fagman, Henrik, Muth, Andreas, Ståhlberg, Anders

“…The majority of patients diagnosed with advanced gastrointestinal stromal tumors (GISTs) are successfully treated with a combination of surgery and tyrosine…”
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Single-cell gene expression profiling using reverse transcription quantitative real-time PCR by Ståhlberg, Anders, Bengtsson, Martin

“…Even in an apparently homogeneous population of cells there are considerable differences between individual cells. A response to a stimulus of a cell…”
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Detection of Circulating Tumor DNA in Plasma: A Potential Biomarker for Esophageal Adenocarcinoma by Egyud, Matthew, Tejani, Mohamedtaki, Pennathur, Arjun, Luketich, James, Sridhar, Praveen, Yamada, Emiko, Ståhlberg, Anders, Filges, Stefan, Krzyzanowski, Paul, Jackson, Jennifer, Kalatskaya, Irina, Jiao, Wei, Nielsen, Gradon, Zhou, Zhongren, Litle, Virginia, Stein, Lincoln, Godfrey, Tony

“…Recent literature has demonstrated the potential of “liquid biopsy” and detection of circulating tumor (ct)DNA as a cancer biomarker. However, to date there is…”
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Identification of genomic binding sites and direct target genes for the transcription factor DDIT3/CHOP by Osman, Ayman, Lindén, Malin, Österlund, Tobias, Vannas, Christoffer, Andersson, Lisa, Escobar, Mandy, Ståhlberg, Anders, Åman, Pierre

“…DDIT3 is a tightly regulated basic leucine zipper (bZIP) transcription factor and key regulator in cellular stress responses. It is involved in a variety of…”
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The secrets of the cell by Kubista, Mikael, Dreyer-Lamm, Jacqueline, Ståhlberg, Anders

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Protective role of reactive astrocytes in brain ischemia by Li, Lizhen, Lundkvist, Andrea, Andersson, Daniel, Wilhelmsson, Ulrika, Nagai, Nobuo, Pardo, Andrea C, Nodin, Christina, Ståhlberg, Anders, Aprico, Karina, Larsson, Kerstin, Yabe, Takeshi, Moons, Lieve, Fotheringham, Andrew, Davies, Ioan, Carmeliet, Peter, Schwartz, Joan P, Pekna, Marcela, Kubista, Mikael, Blomstrand, Fredrik, Maragakis, Nicholas, Nilsson, Michael, Pekny, Milos

“…Reactive astrocytes are thought to protect the penumbra during brain ischemia, but direct evidence has been lacking due to the absence of suitable experimental…”
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Transcriptomic Characterization of the Human Cell Cycle in Individual Unsynchronized Cells by Karlsson, Joakim, Kroneis, Thomas, Jonasson, Emma, Larsson, Erik, Ståhlberg, Anders

“…The highly fine-tuned dynamics of cell cycle gene expression have been intensely studied for several decades. However, some previous observations may be…”
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Defining cell populations with single-cell gene expression profiling: correlations and identification of astrocyte subpopulations by Ståhlberg, Anders, Andersson, Daniel, Aurelius, Johan, Faiz, Maryam, Pekna, Marcela, Kubista, Mikael, Pekny, Milos

“…Single-cell gene expression levels show substantial variations among cells in seemingly homogenous populations. Astrocytes perform many control and regulatory…”
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