Search Results - "Stahl, Rolf AK"
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CC chemokine receptor 5 and renal-transplant survival
Published in The Lancet (British edition) (02-06-2001)“…About 1% of white populations are homozygous carriers of an allele of the gene for the CC chemokine receptor 5 (CCR5) with a 32 bp deletion (CCR5Δ32), which…”
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2
CD2-associated protein and glomerular disease
Published in The Lancet (British edition) (22-11-2003)“…Proteinuria is a major cause of progression in renal disease. The glomerular ultrafiltration barrier, containing highly differentiated podocytes, normally…”
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3
Thrombospondin Type-1 Domain-Containing 7A in Idiopathic Membranous Nephropathy
Published in The New England journal of medicine (11-12-2014)“…Idiopathic membranous nephropathy is associated with autoantibodies against the phospholipase A2 receptor (PLA2R1) in about 70% of patients. This study…”
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A Mechanism for Cancer-Associated Membranous Nephropathy
Published in The New England journal of medicine (19-05-2016)“…The cause of paraneoplastic membranous nephropathy is unclear. In the current case, new expression of THSD7A in a gallbladder carcinoma and the development of…”
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5
THSD7A expression in human cancer
Published in Genes chromosomes & cancer (01-04-2017)“…We recently described a case of a Thrombospondin Type‐1 Domain containing 7A (THSD7A) associated membranous nephropathy in a female patient who was…”
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Function of the Th17/Interleukin‐17A Immune Response in Murine Lupus Nephritis
Published in Arthritis & rheumatology (Hoboken, N.J.) (01-02-2015)“…Objective The CD4+ T cell immune response plays a pivotal role in the immunopathogenesis of human and experimental lupus nephritis, but the contribution of the…”
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Characterization of autoantibodies in primary membranous nephropathy and their clinical significance
Published in Expert review of clinical immunology (01-02-2019)“…: Membranous nephropathy (MN) is the most common cause of a nephrotic syndrome in Caucasian adults. The identification of target antigens in MN in the last…”
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Plasticity of Th17 Cells in Autoimmune Kidney Diseases
Published in The Journal of immunology (1950) (15-07-2016)“…The ability of CD4(+) T cells to differentiate into pathogenic Th1 and Th17 or protective T regulatory cells plays a pivotal role in the pathogenesis of…”
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Glomerulonephritis
Published in Deutsche medizinische Wochenschrift (1946) (01-07-2016)“…Glomerulonephritis encompasses a group of diseases that are characterized by inflammatory glomerular processes and clinically usually present with a nephritic…”
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B‐cell‐derived IL‐10 does not vitally contribute to the clinical course of glomerulonephritis
Published in European journal of immunology (01-03-2014)“…IL‐10‐secreting regulatory B cells have been postulated as negative mediators of inflammation. However, their impact on immune‐mediated diseases requires…”
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Angiotensin II-Induced Mononuclear Leukocyte Interactions with Arteriolar and Venular Endothelium Are Mediated by the Release of Different CC Chemokines
Published in Journal of Immunology (01-05-2006)“…Angiotensin II (Ang-II) is associated with atherogenesis and arterial subendothelial mononuclear leukocyte infiltration. We have demonstrated that Ang-II…”
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Immunoadsorbtion and rituximab therapy in a second living-related kidney transplant patient with recurrent focal segmental glomerulosclerosis
Published in Transplant international (01-12-2007)“…A 29-year-old patient with focal segmental glomerulosclerosis (FSGS) and recurrence of the disease in a living donor kidney transplant received a second…”
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The Novel WD-repeat Protein Morg1 Acts as a Molecular Scaffold for Hypoxia-inducible Factor Prolyl Hydroxylase 3 (PHD3)
Published in The Journal of biological chemistry (31-03-2006)“…Hypoxia-inducible factor-1 (HIF-1), a transcriptional complex composed of an oxygen-sensitive α- and a β-subunit, plays a pivotal role in cellular adaptation…”
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BCA-1/CXCL13 expression is associated with CXCR5-positive B-cell cluster formation in acute renal transplant rejection
Published in Kidney international (01-04-2005)“…BCA-1/CXCL13 expression is associated with CXCR5-positive B-cell cluster formation in acute renal transplant rejection. Recent studies showed a crucial role…”
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Characterization of the transcriptional regulation of the human MT1-MMP gene and association of risk reduction for focal-segmental glomerulosclerosis with two functional promoter SNPs
Published in Nephrology, dialysis, transplantation (01-03-2009)“…Background. The matrix metalloproteinase MT1-MMP (MMP-14) is an important player in wound healing, bone development, angiogenesis, inflammation and tumour…”
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Kidney diseases and chemokines
Published in Current drug targets (01-01-2006)“…Infiltrating inflammatory cells into the kidney mediate the initiation and progression of damage by direct cytotoxicity, the secretion of soluble factors such…”
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15-Deoxy- Delta 12,14 -prostaglandin J2 inhibits INF- Gamma -induced JAK-STAT1 signalling pathway activation and IP-10-CXCL10 expression in mesangial cells
Published in Nephrology, dialysis, transplantation (01-12-2008)“…Background. Activators of the peroxisome proliferator-activated receptor Gamma (PPAR Gamma ), originally found to be implicated in lipid metabolism and glucose…”
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The transcriptional regulation of Podocin (NPHS2) by Lmx1b and a promoter single nucleotide polymorphism
Published in Cellular & molecular biology letters (2009)“…Podocin (NPHS2) is a component of the glomerular slit membrane with major regulatory functions in the renal permeability of proteins. A loss of podocin and a…”
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The chemokine receptor antagonist AOP-RANTES reduces monocyte infiltration in experimental glomerulonephritis
Published in Kidney international (01-12-1999)“…The chemokine receptor antagonist AOP-RANTES reduces monocyte infiltration in experimental glomerulonephritis. This study was designed to evaluate the role of…”
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CELL BIOLOGY - IMMUNOLOGY - PATHOLOGY: The chemokine receptor 5 Delta 32 mutation is associated with increased renal survival in patients with IgA nephropathy
Published in Kidney international (01-01-2005)“…Background. Chemokine receptor 5 (CCR5) plays an important role in the recruitment of monocytes and T cells in inflammation and experimental studies suggest…”
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