Search Results - "Stafford, P"

The dental plaque biofilm matrix by Jakubovics, Nicholas S., Goodman, Steven D., Mashburn‐Warren, Lauren, Stafford, Graham P., Cieplik, Fabian, Darveau, Richard P., Curtis, Michael A.

“…The extracellular matrix is a critical component of microbial biofilms, such as dental plaque, maintaining the spatial arrangement of cells and coordinating…”
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Mechanisms of vascular damage by systemic dissemination of the oral pathogen Porphyromonas gingivalis by Farrugia, Cher, Stafford, Graham P., Potempa, Jan, Wilkinson, Robert N., Chen, Yan, Murdoch, Craig, Widziolek, Magdalena

“…Several studies have unveiled a link between gum disease (periodontitis) and increased risk of cardiovascular disease. It has previously been shown that the…”
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Fusobacterium nucleatum mediates endothelial damage and increased permeability following single species and polymicrobial infection by Farrugia, Cher, Stafford, Graham P, Gains, Ashley F, Cutts, Antonia R, Murdoch, Craig

“…Numerous lines of evidence link periodontal pathobionts and their virulence factors with endothelial damage. Most research has been conducted using single…”
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Aligning tumor mutational burden (TMB) quantification across diagnostic platforms: phase II of the Friends of Cancer Research TMB Harmonization Project by Vega, D.M., Yee, L.M., McShane, L.M., Williams, P.M., Chen, L., Vilimas, T., Fabrizio, D., Funari, V., Newberg, J., Bruce, L.K., Chen, S.-J., Baden, J., Carl Barrett, J., Beer, P., Butler, M., Cheng, J.-H., Conroy, J., Cyanam, D., Eyring, K., Garcia, E., Green, G., Gregersen, V.R., Hellmann, M.D., Keefer, L.A., Lasiter, L., Lazar, A.J., Li, M.-C., MacConaill, L.E., Meier, K., Mellert, H., Pabla, S., Pallavajjalla, A., Pestano, G., Salgado, R., Samara, R., Sokol, E.S., Stafford, P., Budczies, J., Stenzinger, A., Tom, W., Valkenburg, K.C., Wang, X.Z., Weigman, V., Xie, M., Xie, Q., Zehir, A., Zhao, C., Zhao, Y., Stewart, M.D., Allen, J.

“…Tumor mutational burden (TMB) measurements aid in identifying patients who are likely to benefit from immunotherapy; however, there is empirical variability…”
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Spontaneous Preterm Birth Is Associated with Differential Expression of Vaginal Metabolites by Lactobacilli-Dominated Microflora by Stafford, Graham P, Parker, Jennifer L, Amabebe, Emmanuel, Kistler, James, Reynolds, Steven, Stern, Victoria, Paley, Martyn, Anumba, Dilly O C

“…A major challenge in preventing preterm birth (PTB) is identifying women at greatest risk. This pilot study prospectively examined the differences in vaginal…”
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Liquefaction Hazard in the Groningen Region of the Netherlands due to Induced Seismicity by Green, R. A, Bommer, J. J, Stafford, P. J, Maurer, B. W, Kruiver, P. P, Edwards, B, Rodriguez-Marek, A, de Lange, G, Oates, S. J, Storck, T, Omidi, P, Bourne, S. J, van Elk, J

“…AbstractThe operator of the Groningen gas field is leading an effort to quantify the seismic hazard and risk of the region due to induced earthquakes,…”
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A diverse set of Enterococcus-infecting phage provides insight into phage host-range determinants by Alrafaie, Alhassan M., Pyrzanowska, Karolina, Smith, Elspeth M., Partridge, David G., Rafferty, John, Mesnage, Stephane, Shepherd, Joanna, Stafford, Graham P.

“…•Five novel enterococcal phages were isolated and characterized with varied host range.•SHEF14 has a small genome (19.3 Kb) and effectively infects a VRE…”
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The roles of HOXD10 in the development and progression of head and neck squamous cell carcinoma (HNSCC) by Hakami, F, Darda, L, Stafford, P, Woll, P, Lambert, D W, Hunter, K D

“…Background: HOX gene expression is altered in many cancers; previous microarray revealed changes in HOX gene expression in head and neck squamous cell…”
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Addressing limitations in existing ‘simplified’ liquefaction triggering evaluation procedures: application to induced seismicity in the Groningen gas field by Green, R. A., Bommer, J. J., Rodriguez-Marek, A., Maurer, B. W., Stafford, P. J., Edwards, B., Kruiver, P. P., de Lange, G., van Elk, J.

“…The Groningen gas field is one of the largest in the world and has produced over 2000 billion m 3 of natural gas since the start of production in 1963. The…”
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Fusobacterium nucleatum and Tannerella forsythia Induce Synergistic Alveolar Bone Loss in a Mouse Periodontitis Model by SETTEM, Rajendra P, TAHER EL-HASSAN, Ahmed, HONMA, Kiyonobu, STAFFORD, Graham P, SHARMA, Ashu

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Influence of ground motion characteristics on drift demands in steel moment frames designed to Eurocode 8 by Kumar, M., Stafford, P.J., Elghazouli, A.Y.

“…•The influence of ground motion frequency content on drift demands in frames designed to EC8 is examined.•Incremental nonlinear dynamic analyses are carried…”
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Serviceability limit state of vibrations in under-deck cable-stayed bridges accounting for vehicle-structure interaction by Camara, A., Nguyen, K., Ruiz-Teran, A.M., Stafford, P.J.

“…•Under-deck cable-stayed bridges of 80m span are considered.•The response for the serviceability limit-state of vibrations is investigated.•A vehicle-bridge…”
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Long-term effects of a trophic cascade in a large lake ecosystem by Ellis, Bonnie K., Stanford, Jack A., Goodman, Daniel, Stafford, Craig P., Gustafson, Daniel L., Beauchamp, David A., Chess, Dale W., Craft, James A., Deleray, Mark A., Hansen, Barry S., Carpenter, Stephen R.

“…Introductions or invasions of nonnative organisms can mediate major changes in the trophic structure of aquatic ecosystems. Here we document multitrophic level…”
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Zebrafish as a new model to study effects of periodontal pathogens on cardiovascular diseases by Widziolek, Magdalena, Prajsnar, Tomasz K., Tazzyman, Simon, Stafford, Graham P., Potempa, Jan, Murdoch, Craig

“…Porphyromonas gingivalis (Pg ) is a keystone pathogen in the aetiology of chronic periodontitis. However, recent evidence suggests that the bacterium is also…”
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A bacterial glycan core linked to surface (S)-layer proteins modulates host immunity through Th17 suppression by Settem, R P, Honma, K, Nakajima, T, Phansopa, C, Roy, S, Stafford, G P, Sharma, A

“…Tannerella forsythia is a pathogen implicated in periodontitis, an inflammatory disease of the tooth-supporting tissues often leading to tooth loss. This key…”
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Gingipain-dependent degradation of mammalian target of rapamycin pathway proteins by the periodontal pathogen Porphyromonas gingivalis during invasion by Stafford, P., Higham, J., Pinnock, A., Murdoch, C., Douglas, C.W.I., Stafford, G.P., Lambert, D.W.

“…Summary Porphyromonas gingivalis and Tannerella forsythia are gram‐negative pathogens strongly associated with periodontitis. Their abilities to interact,…”
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quantitative proteomic analysis of biofilm adaptation by the periodontal pathogen Tannerella forsythia by Pham, Trong Khoa, Roy, Sumita, Noirel, Josselin, Douglas, Ian, Wright, Phillip C, Stafford, Graham P

“…Tannerella forsythia is a Gram-negative anaerobe that is one of the most prominent inhabitants of the sub-gingival plaque biofilm, which is crucial for causing…”
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Simulations for the development of a ground motion model for induced seismicity in the Groningen gas field, The Netherlands by Edwards, B., Zurek, B., van Dedem, E., Stafford, P. J., Oates, S., van Elk, J., deMartin, B., Bommer, J. J.

“…We present simulations performed for the development of a ground motion model for induced earthquakes in the Groningen gas field. The largest recorded event,…”
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Entropy is a Simple Measure of the Antibody Profile and is an Indicator of Health Status: A Proof of Concept by Wang, Lu, Whittemore, Kurt, Johnston, Stephen Albert, Stafford, Phillip

“…We have previously shown that the diversity of antibodies in an individual can be displayed on chips on which 130,000 peptides chosen from random sequence…”
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Space flight alters bacterial gene expression and virulence and reveals a role for global regulator Hfq by Wilson, J.W, Ott, C.M, zu Bentrup, K. Höner, Ramamurthy, R, Quick, L, Porwollik, S, Cheng, P, McClelland, M, Tsaprailis, G, Radabaugh, T, Hunt, A, Fernandez, D, Richter, E, Shah, M, Kilcoyne, M, Joshi, L, Nelman-Gonzalez, M, Hing, S, Parra, M, Dumars, P, Norwood, K, Bober, R, Devich, J, Ruggles, A, Goulart, C, Rupert, M, Stodieck, L, Stafford, P, Catella, L, Schurr, M.J, Buchanan, K, Morici, L, McCracken, J, Allen, P, Baker-Coleman, C, Hammond, T, Vogel, J, Nelson, R, Pierson, D.L, Stefanyshyn-Piper, H.M, Nickerson, C.A

“…A comprehensive analysis of both the molecular genetic and phenotypic responses of any organism to the space flight environment has never been accomplished…”
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